Purified anti-mouse/rat IL-1β | BioLegend 503501 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-mouse/rat IL-1β

catalog :

503501

quantity :

50 μg

price :

72 USD

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

B122

reactivity :

mouse, rat

application :

western blot, ELISA, immunohistochemistry, neutralization, immunoprecipitation, immunohistochemistry - frozen section, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
ELISA; mouse; loading ...; fig 2d, 3f	Lee P, Selhorst A, Lampe S, Liu Y, Yang Y, Lovett Racke A. Neuron-Specific Vitamin D Signaling Attenuates Microglia Activation and CNS Autoimmunity. Front Neurol. 2020;11:19 pubmed publisher
blocking or activating experiments; mouse; loading ...	Zhang C, Feng J, Du J, Zhuo Z, Yang S, Zhang W, et al. Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity. Cell Mol Immunol. 2018;15:973-982 pubmed publisher
immunohistochemistry; rat; 1:300; fig 8	Qian H, Guan X, Bian Z. FSH aggravates bone loss in ovariectomised rats with experimental periapical periodontitis. Mol Med Rep. 2016;14:2997-3006 pubmed publisher
	Dantis Pereira de Campos T, da Cruz Rodrigues K, Martins Pereira R, Morelli A, da Rocha A, Dos Santos Canciglieri R, et al. Short-Term Combined Exercise Improves Inflammatory Profile in the Retina of Obese Mice. Int J Mol Sci. 2020;21: pubmed publisher
	Pahari S, Negi S, Aqdas M, Arnett E, Schlesinger L, Agrewala J. Induction of autophagy through CLEC4E in combination with TLR4: an innovative strategy to restrict the survival of Mycobacterium tuberculosis. Autophagy. 2020;16:1021-1043 pubmed publisher
	Nie S, Wang X, Wang H. NLRP3 Inflammasome Mediated Interleukin-1β Production in Cancer-Associated Fibroblast Contributes to ALA-PDT for Cutaneous Squamous Cell Carcinoma. Cancer Manag Res. 2019;11:10257-10267 pubmed publisher
	Pereira R, Rodrigues K, Anaruma C, Sant Ana M, de Campos T, Gaspar R, et al. Short-term strength training reduces gluconeogenesis and NAFLD in obese mice. J Endocrinol. 2019;241:59-70 pubmed publisher
	den Hartigh A, Fink S. Pyroptosis Induction and Detection. Curr Protoc Immunol. 2018;122:e52 pubmed publisher
	Zou B, Jiang W, Han H, Li J, Mao W, Tang Z, et al. Acyloxyacyl hydrolase promotes the resolution of lipopolysaccharide-induced acute lung injury. PLoS Pathog. 2017;13:e1006436 pubmed publisher

product information

Antigen :

IL-1beta

Apps. Abbrev. :

ELISA Capture, ELISPOT Capture, Depletion, IHC-F, IP, Neut, Western Blotting

Cat # :

503501

Clone :

B122

Item :

Purified anti-mouse/rat IL-1β

Isotype :

Armenian Hamster IgG

Other Names :

Interleukin-1β, Catabolin, Hematopoietin-1 (H1), IFNβ-inducing factor, Interleukin-β, Osteoclast activating factor (OAF)

Size :

50 μg

Price (USD) :

72 USD

Reactivity :

Mouse, Rat

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

PURE

Immunogen :

E. coli -expressed, recombinant mouse IL-1β

Application Notes :

ELISA or ELISPOT Capture 3 : The purified B122 antibody is useful as the capture antibody in a mouse IL-1ß sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated Poly5158 antibody (Cat. No. 515801) as the detecting antibody. The LEAF™ purified antibody is suggested for ELISPOT capture. Certain formats of clone B122 have been reported for in vitro neutralization of IL-1ß bioactivity 1 , in vivo cytokine depletion 5 , immunohistochemical staining of frozen sections 6 , Western blotting 7 , and the study of endotoxin shock 8 .

more info or order :

BioLegend product webpage