Purified anti-mouse IL-1α | BioLegend 503202 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-mouse IL-1α

catalog :

503202

quantity :

500 μg

price :

136 USD

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

ALF-161

reactivity :

mouse

application :

western blot, ELISA, immunoprecipitation, flow cytometry, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; loading ... flow cytometry; mouse	Zhang C, Feng J, Du J, Zhuo Z, Yang S, Zhang W, et al. Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity. Cell Mol Immunol. 2018;15:973-982 pubmed publisher
	Jiao S, Subudhi S, Aparicio A, Ge Z, Guan B, Miura Y, et al. Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy. Cell. 2019;179:1177-1190.e13 pubmed publisher
	Lee B, Jo Y, Kim G, Ali L, Sohn D, Lee S, et al. Specific Inhibition of Soluble γc Receptor Attenuates Collagen-Induced Arthritis by Modulating the Inflammatory T Cell Responses. Front Immunol. 2019;10:209 pubmed publisher
	Fang D, Cui K, Mao K, Hu G, Li R, Zheng M, et al. Transient T-bet expression functionally specifies a distinct T follicular helper subset. J Exp Med. 2018;215:2705-2714 pubmed publisher
	Arnold I, Artola Borán M, Tallón de Lara P, Kyburz A, Taube C, OTTEMANN K, et al. Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. J Exp Med. 2018;215:2055-2072 pubmed publisher
	Matsuo K, Nagakubo D, Komori Y, Fujisato S, Takeda N, Kitamatsu M, et al. CCR4 Is Critically Involved in Skin Allergic Inflammation of BALB/c Mice. J Invest Dermatol. 2018;138:1764-1773 pubmed publisher

product information

Antigen :

IL-1alpha

Apps. Abbrev. :

ELISA Capture, IP, WB

Cat # :

503202

Clone :

ALF-161

Item :

Purified anti-mouse IL-1α

Isotype :

Armenian Hamster IgG

Other Names :

Interleukin-1α, Lymphocyte-activating factor (LAF), Endogenous pyrogen (EP), Leukocyte endogenous mediator (LEM), Mononuclear cell factor (MCF/MNCF)

Size :

500 μg

Price (USD) :

136 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

PURE

Immunogen :

E. coli - expressed, recombinant mouse IL-1

Application Notes :

ELISA or ELISPOT Capture: The purified ALF-161 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated Poly5034 antibody (Cat. No. 503401) as the detecting antibody. The Ultra-LEAF™ purified antibody is suggested for ELISPOT capture.ELISA Capture: The purified ALF-161 antibody is useful as the capture antibody in a sandwich ELISA when used in conjunction with the biotinylated BL1a-89 antibody (Cat. Nos. 512503 & 512504) as the detection antibody and recombinant mouse IL-1a (Cat. No. 580309) as the standard.Neutralization: Clone ALF-161 has been described to have IL-1a neutralizing properties based on the in vivo mice model^3. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended (Cat. No. 503207-503212).;

more info or order :

BioLegend product webpage