Brilliant Violet 421™ anti-human TNF-α | BioLegend 502931 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 421™ anti-human TNF-α

catalog :

502931

quantity :

25 tests

price :

190 USD

clonality :

monoclonal

host :

mouse

conjugate :

BV421

clone name :

MAb11

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 17

Reference
Shen W, Li H, Zha A, Luo R, Zhang Y, Luo C, et al. Platelets reprogram monocyte functions by secreting MMP-9 to benefit postoperative outcomes following acute aortic dissection. iScience. 2023;26:106805 pubmed publisher
Tamaoki N, Siebert S, Maeda T, Ha N, Good M, Huang Y, et al. Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells. Cell Rep Methods. 2023;3:100460 pubmed publisher
Lee H, Park H, Lee S. Rapamycin Restores Different Patterns of Cytokine Expression to Dexamethasone Treatment on CD14++CD16+ Monocytes from Steroid-Resistant Asthma Patients. Biol Pharm Bull. 2023;46:542-551 pubmed publisher
Saeland E, van der Fits L, Bolder R, Heemskerk van der Meer M, Drijver J, van Polanen Y, et al. Combination Ad26.RSV.preF/preF protein vaccine induces superior protective immunity compared with individual vaccine components in preclinical models. NPJ Vaccines. 2023;8:45 pubmed publisher
Vatzia E, Feest K, McNee A, Manjegowda T, Carr B, Paudyal B, et al. Immunization with matrix-, nucleoprotein and neuraminidase protects against H3N2 influenza challenge in pH1N1 pre-exposed pigs. NPJ Vaccines. 2023;8:19 pubmed publisher
Pu x161 nik J, Monzon Posadas W, Zorn J, Peters K, Baum M, Proksch H, et al. SARS-CoV-2 humoral and cellular immunity following different combinations of vaccination and breakthrough infection. Nat Commun. 2023;14:572 pubmed publisher
Ogura H, Gohda J, Lu X, Yamamoto M, Takesue Y, Son A, et al. Dysfunctional Sars-CoV-2-M protein-specific cytotoxic T lymphocytes in patients recovering from severe COVID-19. Nat Commun. 2022;13:7063 pubmed publisher
Myers J, Schirm D, Bendzick L, Hopps R, Selleck C, Hinderlie P, et al. Balanced engagement of activating and inhibitory receptors mitigates human NK cell exhaustion. JCI Insight. 2022;7: pubmed publisher
Fitzgerald K, Smith M, Kim S, Sotirchos E, Kornberg M, Douglas M, et al. Multi-omic evaluation of metabolic alterations in multiple sclerosis identifies shifts in aromatic amino acid metabolism. Cell Rep Med. 2021;2:100424 pubmed publisher
Somogyi E, Csiszovszki Z, Moln xe1 r L, L x151 rincz O, T xf3 th J, Pattijn S, et al. A Peptide Vaccine Candidate Tailored to Individuals' Genetics Mimics the Multi-Targeted T Cell Immunity of COVID-19 Convalescent Subjects. Front Genet. 2021;12:684152 pubmed publisher
Seo Y, Suh Y, Ryu J, Jang H, Oh H, Koo B, et al. Soluble Spike DNA Vaccine Provides Long-Term Protective Immunity against SARS-CoV-2 in Mice and Nonhuman Primates. Vaccines (Basel). 2021;9: pubmed publisher
Lindesmith L, Brewer Jensen P, Mallory M, Jensen K, Yount B, Costantini V, et al. Virus-Host Interactions Between Nonsecretors and Human Norovirus. Cell Mol Gastroenterol Hepatol. 2020;10:245-267 pubmed publisher
Xu X, Davelaar N, Mus A, Asmawidjaja P, Hazes J, Baeten D, et al. Interleukin-17A Is Produced by CD4+ but Not CD8+ T Cells in Synovial Fluid Following T Cell Receptor Activation and Regulates Different Inflammatory Mediators Compared to Tumor Necrosis Factor in a Model of Psoriatic Arthritis Synovitis. Arthritis Rheumatol. 2020;72:1303-1313 pubmed publisher
Rieckmann K, Seydel A, Klose K, Alber G, Baums C, Schütze N. Vaccination with the immunoglobulin M-degrading enzyme of Streptococcus suis, Ide Ssuis, leads to protection against a highly virulent serotype 9 strain. Vaccine X. 2019;3:100046 pubmed publisher
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product information

Antigen :

TNF-alpha

Apps. Abbrev. :

ICFC, FC

Cat # :

502931

Clone :

MAb11

Item :

Brilliant Violet 421™ anti-human TNF-α

Isotype :

Mouse IgG1, κ

Other Names :

Tumor necrosis factor-α, Cachectin, Necrosin, Macrophage cytotoxic factor (MCF), Differentiation inducing factor (DIF), TNFSF2

Size :

25 tests

Price (USD) :

190 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

BV421

Immunogen :

E. coli -expressed, recombinant human TNF-α

Application Notes :

ELISA or ELISPOT Detection: The biotinylated MAb11 antibody is useful as the detection antibody in a sandwich ELISA or ELISPOT, when used in conjunction with the purified MAb1 antibody (Cat. No. 502802/502804) as the capture antibody.Flow Cytometry^3,5,6,10: The fluorochrome-labeled MAb11 antibody is useful for intracellular and membrane-bound immunofluorescent staining and flow cytometric analysis to identify TNF-a-producing cells within mixed cell populations.Additional reported applications (for the relevant formats) include: neutralization^1,2, immunohistochemical staining of paraformaldehyde-fixed, saponin-treated frozen tissue sections^4 and acetone-fixed frozen tissue sections^8, immunocytochemistry^7, and immunofluorescence^9. The MAb11 antibody can neutralize the bioactivity of natural or recombinant TNF-a.Note: For testing human TNF-a in serum or plasma, BioLegend's ELISA Max™ Sets (Cat. No. 430201 to 430206) are specially developed and recommended. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of human TNF-a bioactivity (Cat. No. 502922).The Purified MAb1 antibody is useful in neutralization^2 and as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated MAb11 antibody (Cat. No. 502904/502914) as the detecting antibody.Clone MAb11 cross-reacts to Cat^11;

more info or order :

BioLegend product webpage