| Published Application/Species/Sample/Dilution | Reference |
|---|
- flow cytometry; human; loading ...; fig 4i
| Hickman T, Choi E, Whiteman K, Muralidharan S, Pai T, Johnson T, et al. BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved anti-cell line derived tumor xenograft activity. PLoS ONE. 2022;17:e0266980 pubmed publisher |
- mass cytometry; human; loading ...; fig 4e
- flow cytometry; human; loading ...; fig 2d
| Ingelfinger F, Krishnarajah S, Kramer M, Utz S, Galli E, Lutz M, et al. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta Neuropathol. 2021;141:901-915 pubmed publisher |
- flow cytometry; human; 3:50; loading ...; fig 4a
| Gregorova M, Morse D, Brignoli T, Steventon J, Hamilton F, Albur M, et al. Post-acute COVID-19 associated with evidence of bystander T-cell activation and a recurring antibiotic-resistant bacterial pneumonia. elife. 2020;9: pubmed publisher |
- flow cytometry; human; fig 4b
| Marotte L, Simon S, Vignard V, Dupré E, Gantier M, Cruard J, et al. Increased antitumor efficacy of PD-1-deficient melanoma-specific human lymphocytes. J Immunother Cancer. 2020;8: pubmed publisher |
- flow cytometry; human; loading ...; fig 6d
| Lynn R, Weber E, Sotillo E, Gennert D, Xu P, Good Z, et al. c-Jun overexpression in CAR T cells induces exhaustion resistance. Nature. 2019;576:293-300 pubmed publisher |
- flow cytometry; human; loading ...; fig 1b
| Meckiff B, Ladell K, McLaren J, Ryan G, Leese A, James E, et al. Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells. J Immunol. 2019;203:1276-1287 pubmed publisher |
- flow cytometry; human; loading ...; fig 3b
| van de Garde M, van Westen E, Poelen M, Rots N, van Els C. Prediction and Validation of Immunogenic Domains of Pneumococcal Proteins Recognized by Human CD4+ T Cells. Infect Immun. 2019;87: pubmed publisher |
- flow cytometry; human; loading ...; fig 6a
| Banki Z, Krabbendam L, Klaver D, Leng T, Kruis S, Mehta H, et al. Antibody opsonization enhances MAIT cell responsiveness to bacteria via a TNF-dependent mechanism. Immunol Cell Biol. 2019;97:538-551 pubmed publisher |
- flow cytometry; human; fig 3f
| Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed publisher |
- flow cytometry; human; loading ...; fig 8d
| Aulicino A, Rue Albrecht K, Preciado Llanes L, Napolitani G, Ashley N, Cribbs A, et al. Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets. Nat Commun. 2018;9:4883 pubmed publisher |
- flow cytometry; human; loading ...; fig 3b
| Li N, van Unen V, Höllt T, Thompson A, van Bergen J, Pezzotti N, et al. Mass cytometry reveals innate lymphoid cell differentiation pathways in the human fetal intestine. J Exp Med. 2018;215:1383-1396 pubmed publisher |
- flow cytometry; human; loading ...; fig 2h
| Pizzolla A, Nguyen T, Sant S, Jaffar J, Loudovaris T, Mannering S, et al. Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles. J Clin Invest. 2018;128:721-733 pubmed publisher |
- flow cytometry; rhesus macaque; loading ...
| Roberts E, Carnathan D, Li H, Shaw G, Silvestri G, Betts M. Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques. PLoS Pathog. 2016;12:e1006135 pubmed publisher |
- flow cytometry; human; fig s1e
| Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed publisher |
- flow cytometry; human; loading ...; fig 6a
| Gadd V, Patel P, Jose S, Horsfall L, Powell E, Irvine K. Altered Peripheral Blood Monocyte Phenotype and Function in Chronic Liver Disease: Implications for Hepatic Recruitment and Systemic Inflammation. PLoS ONE. 2016;11:e0157771 pubmed publisher |
- flow cytometry; African green monkey; loading ...; fig 1b
| Neumann B, Shi T, Gan L, Klippert A, Daskalaki M, Stolte Leeb N, et al. Comprehensive panel of cross-reacting monoclonal antibodies for analysis of different immune cells and their distribution in the common marmoset (Callithrix jacchus). J Med Primatol. 2016;45:139-46 pubmed publisher |
- flow cytometry; pigs ; loading ...; fig 7d
| Bähr A, Käser T, Kemter E, Gerner W, Kurome M, Baars W, et al. Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs. PLoS ONE. 2016;11:e0155676 pubmed publisher |
- flow cytometry; human; fig 1
| Lee Chang C, Bodogai M, Moritoh K, Chen X, Wersto R, Sen R, et al. Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers. J Immunol. 2016;196:3385-97 pubmed publisher |
- flow cytometry; human; loading ...; fig 4b
| Vallera D, Felices M, McElmurry R, McCullar V, Zhou X, Schmohl J, et al. IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function. Clin Cancer Res. 2016;22:3440-50 pubmed publisher |
- immunocytochemistry; human; fig 6
| Schnorfeil F, Lichtenegger F, Emmerig K, Schlueter M, Neitz J, Draenert R, et al. T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment. J Hematol Oncol. 2015;8:93 pubmed publisher |
- flow cytometry; human; fig 1
| Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed publisher |
| Talker S, Koinig H, Stadler M, Graage R, Klingler E, Ladinig A, et al. Magnitude and kinetics of multifunctional CD4+ and CD8β+ T cells in pigs infected with swine influenza A virus. Vet Res. 2015;46:52 pubmed publisher |
- flow cytometry; human; fig 1
| Boyle M, Jagannathan P, Bowen K, McIntyre T, Vance H, Farrington L, et al. Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations. J Infect Dis. 2015;212:416-25 pubmed publisher |
| Gerner W, Talker S, Koinig H, Sedlak C, Mair K, Saalmüller A. Phenotypic and functional differentiation of porcine αβ T cells: current knowledge and available tools. Mol Immunol. 2015;66:3-13 pubmed publisher |
| Sueur C, Lupo J, Mas P, Morand P, Boyer V. Difference in cytokine production and cell cycle progression induced by Epstein-Barr virus Lmp1 deletion variants in Kmh2, a Hodgkin lymphoma cell line. Virol J. 2014;11:94 pubmed publisher |
- flow cytometry; human; loading ...; fig 3a
| Duggal N, Beswetherick A, Upton J, Hampson P, Phillips A, Lord J. Depressive symptoms in hip fracture patients are associated with reduced monocyte superoxide production. Exp Gerontol. 2014;54:27-34 pubmed publisher |
- flow cytometry; human; loading ...; tbl 2
| Krishnan S, Wilson E, Sheikh V, Rupert A, Mendoza D, Yang J, et al. Evidence for innate immune system activation in HIV type 1-infected elite controllers. J Infect Dis. 2014;209:931-9 pubmed publisher |
| Marin N, Paris S, Rojas M, Garcia L. Functional profile of CD4+ and CD8+ T cells in latently infected individuals and patients with active TB. Tuberculosis (Edinb). 2013;93:155-66 pubmed publisher |
| Baumer Y, Singh K, Baez A, Gutierrez Huerta C, Chen L, Igboko M, et al. Social Determinants modulate NK cell activity via obesity, LDL, and DUSP1 signaling. bioRxiv. 2023;: pubmed publisher |
| Chancellor A, Alan Simmons R, Khanolkar R, Nosi V, Beshirova A, Berloffa G, et al. Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J Exp Med. 2023;220: pubmed publisher |
| Brightman S, Naradikian M, Thota R, Becker A, Montero L, Bahmanof M, et al. Tumor cells fail to present MHC-II restricted epitopes derived from oncogenes to CD4+ T cells. JCI Insight. 2022;: pubmed publisher |
| Lontos K, Wang Y, Colbert M, Kumar A, Joshi S, Philbin M, et al. Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biology. Oncoimmunology. 2022;11:2131229 pubmed publisher |
| Zhong C, Peng L, Tao B, Yin S, Lyu L, Ding H, et al. TDO2 and tryptophan metabolites promote kynurenine/AhR signals to facilitate glioma progression and immunosuppression. Am J Cancer Res. 2022;12:2558-2575 pubmed |
| Fang F, Cao W, Mu Y, Okuyama H, Li L, Qiu J, et al. IL-4 prevents adenosine-mediated immunoregulation by inhibiting CD39 expression. JCI Insight. 2022;7: pubmed publisher |
| Fielding C, Sabberwal P, Williamson J, Greenwood E, Crozier T, Zelek W, et al. SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies. elife. 2022;11: pubmed publisher |
| Stensland Z, Coleman B, Rihanek M, Baxter R, Gottlieb P, Hsieh E, et al. Peripheral immunophenotyping of AITD subjects reveals alterations in immune cells in pediatric vs adult-onset AITD. iScience. 2022;25:103626 pubmed publisher |
| Vieira V, Millar J, Adland E, Muenchhoff M, Roider J, Guash C, et al. Robust HIV-specific CD4+ and CD8+ T-cell responses distinguish elite control in adolescents living with HIV from viremic nonprogressors. AIDS. 2022;36:95-105 pubmed publisher |
| Mishra A, Lai G, Yao L, Aung T, Shental N, Rotter Maskowitz A, et al. Microbial exposure during early human development primes fetal immune cells. Cell. 2021;184:3394-3409.e20 pubmed publisher |
| Burckhardt C, Minna J, Danuser G. SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt. Dev Cell. 2021;56:1164-1181.e12 pubmed publisher |
| Kilgour M, MacPherson S, Zacharias L, Ellis A, Sheldon R, Liu E, et al. 1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer. Sci Adv. 2021;7: pubmed publisher |
| Tan T, Rijal P, Rahikainen R, Keeble A, Schimanski L, Hussain S, et al. A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses. Nat Commun. 2021;12:542 pubmed publisher |
| Pedrera M, Macchi F, McLean R, Franceschi V, Thakur N, Russo L, et al. Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs. Vaccines (Basel). 2020;8: pubmed publisher |
| Cogswell A, Maski K, Scammell T, Tucker D, Orban Z, Koralnik I. Children with Narcolepsy type 1 have increased T-cell responses to orexins. Ann Clin Transl Neurol. 2019;6:2566-2572 pubmed publisher |
| Cai D, Li J, Liu D, Hong S, Qiao Q, Sun Q, et al. Tumor-expressed B7-H3 mediates the inhibition of antitumor T-cell functions in ovarian cancer insensitive to PD-1 blockade therapy. Cell Mol Immunol. 2019;: pubmed publisher |
| Del Alcazar D, Wang Y, He C, Wendel B, Del Rio Estrada P, Lin J, et al. Mapping the Lineage Relationship between CXCR5+ and CXCR5- CD4+ T Cells in HIV-Infected Human Lymph Nodes. Cell Rep. 2019;28:3047-3060.e7 pubmed publisher |
| Reiske L, Schmucker S, Steuber J, Stefanski V. Glucocorticoids and Catecholamines Affect in Vitro Functionality of Porcine Blood Immune Cells. Animals (Basel). 2019;9: pubmed publisher |
| Tripathi T, Yin W, Xue Y, Zurawski S, Fujita H, Hanabuchi S, et al. Central Roles of OX40L-OX40 Interaction in the Induction and Progression of Human T Cell-Driven Acute Graft-versus-Host Disease. Immunohorizons. 2019;3:110-120 pubmed publisher |
| Pararasa C, Zhang N, Tull T, Chong M, Siu J, Guesdon W, et al. Reduced CD27-IgD- B Cells in Blood and Raised CD27-IgD- B Cells in Gut-Associated Lymphoid Tissue in Inflammatory Bowel Disease. Front Immunol. 2019;10:361 pubmed publisher |
| Schlenner S, Pasciuto E, Lagou V, Burton O, Prezzemolo T, Junius S, et al. NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology. Ann Rheum Dis. 2019;78:342-349 pubmed publisher |
| Kim C, Hu B, Jadhav R, Jin J, Zhang H, Cavanagh M, et al. Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells. Cell Rep. 2018;25:2148-2162.e5 pubmed publisher |
| Wang W, Marinis J, Beal A, Savadkar S, Wu Y, Khan M, et al. RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer. Cancer Cell. 2018;34:757-774.e7 pubmed publisher |
| Chen H, van der Touw W, Wang Y, Kang K, Mai S, Zhang J, et al. Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity. J Clin Invest. 2018;128:5647-5662 pubmed publisher |
| Bradley T, Peppa D, Pedroza Pacheco I, Li D, Cain D, Henao R, et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. Cell. 2018;175:387-399.e17 pubmed publisher |
| Kauffman K, Sallin M, Hoft S, Sakai S, Moore R, Wilder Kofie T, et al. Limited Pulmonary Mucosal-Associated Invariant T Cell Accumulation and Activation during Mycobacterium tuberculosis Infection in Rhesus Macaques. Infect Immun. 2018;86: pubmed publisher |
| Petrelli A, Mijnheer G, Hoytema van Konijnenburg D, van der Wal M, Giovannone B, Mocholí E, et al. PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation. J Clin Invest. 2018;128:4669-4681 pubmed publisher |
| Wang H, D Souza C, Lim X, Kostenko L, Pediongco T, Eckle S, et al. MAIT cells protect against pulmonary Legionella longbeachae infection. Nat Commun. 2018;9:3350 pubmed publisher |
| Cichocki F, Wu C, Zhang B, Felices M, Tesi B, Tuininga K, et al. ARID5B regulates metabolic programming in human adaptive NK cells. J Exp Med. 2018;215:2379-2395 pubmed publisher |
| Levin M, Kroehl M, Johnson M, Hammes A, Reinhold D, Lang N, et al. Th1 memory differentiates recombinant from live herpes zoster vaccines. J Clin Invest. 2018;128:4429-4440 pubmed publisher |
| Kirkling M, Cytlak U, Lau C, Lewis K, Resteu A, Khodadadi Jamayran A, et al. Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells. Cell Rep. 2018;23:3658-3672.e6 pubmed publisher |
| Ramsingh A, Gray S, Reilly A, Koday M, Bratt D, Koday M, et al. Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation. PLoS ONE. 2018;13:e0198154 pubmed publisher |
| Holzer B, Morgan S, Matsuoka Y, Edmans M, Salguero F, Everett H, et al. Comparison of Heterosubtypic Protection in Ferrets and Pigs Induced by a Single-Cycle Influenza Vaccine. J Immunol. 2018;200:4068-4077 pubmed publisher |
| Miles J, Tan M, Dolton G, Edwards E, Galloway S, Laugel B, et al. Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. J Clin Invest. 2018;128:1569-1580 pubmed publisher |
| Chen D, Xie J, Fiskesund R, Dong W, Liang X, Lv J, et al. Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype. Nat Commun. 2018;9:873 pubmed publisher |
| Chang Z, Lorenzini M, Chen X, Tran U, Bangayan N, Chen Y. Rewiring T-cell responses to soluble factors with chimeric antigen receptors. Nat Chem Biol. 2018;14:317-324 pubmed publisher |
| Guo T, Koo M, Kagoya Y, Anczurowski M, Wang C, Saso K, et al. A Subset of Human Autoreactive CD1c-Restricted T Cells Preferentially Expresses TRBV4-1+ TCRs. J Immunol. 2018;200:500-511 pubmed publisher |
| Prezzemolo T, van Meijgaarden K, Franken K, Caccamo N, Dieli F, Ottenhoff T, et al. Detailed characterization of human Mycobacterium tuberculosis specific HLA-E restricted CD8+ T-cells. Eur J Immunol. 2017;: pubmed publisher |
| Hydes T, Noll A, Salinas Riester G, Abuhilal M, Armstrong T, Hamady Z, et al. IL-12 and IL-15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells. Immun Inflamm Dis. 2018;6:34-46 pubmed publisher |
| Teigler J, Zelinskyy G, Eller M, Bolton D, Marovich M, Gordon A, et al. Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection. J Virol. 2017;91: pubmed publisher |
| Cichocki F, Valamehr B, Bjordahl R, Zhang B, Rezner B, Rogers P, et al. GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity. Cancer Res. 2017;77:5664-5675 pubmed publisher |
| Zhao J, Alshukairi A, Baharoon S, Ahmed W, Bokhari A, Nehdi A, et al. Recovery from the Middle East respiratory syndrome is associated with antibody and T-cell responses. Sci Immunol. 2017;2: pubmed publisher |
| Schwerd T, Twigg S, Aschenbrenner D, Manrique S, Miller K, Taylor I, et al. A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis. J Exp Med. 2017;214:2547-2562 pubmed publisher |
| Almeida V, Avelar Freitas B, Santos M, Costa L, Silva T, Pereira W, et al. Inhibitory effect of the Pseudobrickellia brasiliensis (Spreng) R.M. King & H. Rob. aqueous extract on human lymphocyte proliferation and IFN-? and TNF-? production in vitro. Braz J Med Biol Res. 2017;50:e5163 pubmed publisher |
| Ott P, Hu Z, Keskin D, Shukla S, Sun J, Bozym D, et al. An immunogenic personal neoantigen vaccine for patients with melanoma. Nature. 2017;547:217-221 pubmed publisher |
| Cao D, Cao Q, Subramaniam S, Yugo D, Heffron C, Rogers A, et al. Pig model mimicking chronic hepatitis E virus infection in immunocompromised patients to assess immune correlates during chronicity. Proc Natl Acad Sci U S A. 2017;114:6914-6923 pubmed publisher |
| Qaqish A, Huang D, Chen C, Zhang Z, Wang R, Li S, et al. Adoptive Transfer of Phosphoantigen-Specific ?? T Cell Subset Attenuates Mycobacterium tuberculosis Infection in Nonhuman Primates. J Immunol. 2017;198:4753-4763 pubmed publisher |
| Lavin Y, Kobayashi S, Leader A, Amir E, Elefant N, Bigenwald C, et al. Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses. Cell. 2017;169:750-765.e17 pubmed publisher |
| Huang A, Postow M, Orlowski R, Mick R, Bengsch B, Manne S, et al. T-cell invigoration to tumour burden ratio associated with anti-PD-1 response. Nature. 2017;545:60-65 pubmed publisher |
| Dallari S, Macal M, Loureiro M, Jo Y, Swanson L, Hesser C, et al. Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses. Nat Commun. 2017;8:14830 pubmed publisher |
| Izawa K, Martin E, Soudais C, Bruneau J, Boutboul D, Rodriguez R, et al. Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection. J Exp Med. 2017;214:73-89 pubmed publisher |
| Nicolet B, Guislain A, Wolkers M. Combined Single-Cell Measurement of Cytokine mRNA and Protein Identifies T Cells with Persistent Effector Function. J Immunol. 2017;198:962-970 pubmed publisher |
| Sekine T, Marin D, Cao K, Li L, Mehta P, Shaim H, et al. Specific combinations of donor and recipient KIR-HLA genotypes predict for large differences in outcome after cord blood transplantation. Blood. 2016;128:297-312 pubmed publisher |
| Martin E, Palmic N, Sanquer S, Lenoir C, Hauck F, Mongellaz C, et al. CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation. Nature. 2014;510:288-92 pubmed publisher |
| Mysliwska J, Smardzewski M, Marek Trzonkowska N, Myśliwiec M, Raczynska K. Expansion of CD14+CD16+ monocytes producing TNF-? in complication-free diabetes type 1 juvenile onset patients. Cytokine. 2012;60:309-17 pubmed publisher |
