Purified anti-human TNF-α | BioLegend 502802 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human TNF-α

catalog :

502802

quantity :

500 μg

price :

235 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MAb1

reactivity :

human

application :

western blot, ELISA, neutralization, dot blot

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
dot blot; human; tbl s1	Lu Y, Xue Q, Eisele M, Sulistijo E, Brower K, Han L, et al. Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands. Proc Natl Acad Sci U S A. 2015;112:E607-15 pubmed publisher
	Rodriguez Salazar C, Recalde Reyes D, Bedoya J, Padilla Sanabria L, Castaño Osorio J, Giraldo M. In Vitro Inhibition of Replication of Dengue Virus Serotypes 1-4 by siRNAs Bound to Non-Toxic Liposomes. Viruses. 2022;14: pubmed publisher
	Li M, Wang W, Cheng Y, Zhang X, Zhao N, Tan Y, et al. Tumor necrosis factor α upregulates the bile acid efflux transporter OATP3A1 via multiple signaling pathways in cholestasis. J Biol Chem. 2022;298:101543 pubmed publisher
	Schwaderer J, Phan T, Glöckner A, Delp J, Leist M, Brunner T, et al. Pharmacological LRH-1/Nr5a2 inhibition limits pro-inflammatory cytokine production in macrophages and associated experimental hepatitis. Cell Death Dis. 2020;11:154 pubmed publisher
	Jiao S, Subudhi S, Aparicio A, Ge Z, Guan B, Miura Y, et al. Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy. Cell. 2019;179:1177-1190.e13 pubmed publisher
	Lee B, Jo Y, Kim G, Ali L, Sohn D, Lee S, et al. Specific Inhibition of Soluble γc Receptor Attenuates Collagen-Induced Arthritis by Modulating the Inflammatory T Cell Responses. Front Immunol. 2019;10:209 pubmed publisher
	Arnold I, Artola Borán M, Tallón de Lara P, Kyburz A, Taube C, OTTEMANN K, et al. Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. J Exp Med. 2018;215:2055-2072 pubmed publisher
	Hua J, Inomata T, Chen Y, Foulsham W, Stevenson W, Shiang T, et al. Pathological conversion of regulatory T cells is associated with loss of allotolerance. Sci Rep. 2018;8:7059 pubmed publisher
	Hammer Q, Rückert T, Dunst J, Romagnani C. Adaptive Natural Killer Cells Integrate Interleukin-18 during Target-Cell Encounter. Front Immunol. 2017;8:1976 pubmed publisher
	Varadarajan N, Kwon D, Law K, Ogunniyi A, Anahtar M, Richter J, et al. Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving. Proc Natl Acad Sci U S A. 2012;109:3885-90 pubmed publisher
	Ivanov V, Ronai Z. Down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells. J Biol Chem. 1999;274:14079-89 pubmed

product information

Antigen :

TNF-alpha

Apps. Abbrev. :

ELISA Capture, Neut, WB

Cat # :

502802

Clone :

MAb1

Item :

Purified anti-human TNF-α

Isotype :

Mouse IgG1, κ

Other Names :

Tumor necrosis factor-α, Cachectin, Necrosin, Macrophage cytotoxic factor (MCF), Differentiation inducing factor (DIF), TNFSF2

Size :

500 μg

Price (USD) :

235 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

E. coli -expressed, recombinant human TNF-α

Application Notes :

ELISA or ELISPOT Capture: The purified MAb1 antibody is useful in neutralization^2 and as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated MAb11 antibody (Cat. No. 502904/502914) as the detecting antibody. The Ultra-LEAF™ purified antibody is suggested for ELISPOT capture.;

more info or order :

BioLegend product webpage