Brilliant Violet 711™ anti-human IFN-γ | BioLegend 502540 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 711™ anti-human IFN-γ

catalog :

502540

quantity :

100 tests

price :

446 USD

clonality :

monoclonal

host :

mouse

conjugate :

BV711

clone name :

4S.B3

reactivity :

human

application :

immunocytochemistry

more info or order :

BioLegend product webpage

citations: 14

Reference
Jiang X, Lin J, Shangguan C, Wang X, Xiang B, Chen J, et al. Intrinsic RIG-I restrains STAT5 activation to modulate antitumor activity of CD8+ T cells. J Clin Invest. 2023;133: pubmed publisher
Cai Z, Chen J, Yu Z, Li H, Liu Z, Deng D, et al. BCAT2 Shapes a Noninflamed Tumor Microenvironment and Induces Resistance to Anti-PD-1/PD-L1 Immunotherapy by Negatively Regulating Proinflammatory Chemokines and Anticancer Immunity. Adv Sci (Weinh). 2023;10:e2207155 pubmed publisher
Du Bruyn E, Stek C, Daroowala R, Said Hartley Q, Hsiao M, Schäfer G, et al. Effects of tuberculosis and/or HIV-1 infection on COVID-19 presentation and immune response in Africa. Nat Commun. 2023;14:188 pubmed publisher
Ogishi M, Yang R, Rodriguez R, Golec D, Martin E, Philippot Q, et al. Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosis. J Exp Med. 2023;220: pubmed publisher
Sun Y, Zhang J, Tong L, Lü J, Chen T, Wei Q, et al. Protocol for evaluating CD8+ T cell-mediated immunity in latently SHIV-infected rhesus macaques with HIV fusion-inhibitory lipopeptide monotherapy. STAR Protoc. 2022;3:101479 pubmed publisher
Lozano Rodríguez R, Valentín Quiroga J, Avendaño Ortiz J, Martín Quirós A, Pascual Iglesias A, Terrón Arcos V, et al. Cellular and humoral functional responses after BNT162b2 mRNA vaccination differ longitudinally between naive and subjects recovered from COVID-19. Cell Rep. 2022;38:110235 pubmed publisher
Mathewson N, Ashenberg O, Tirosh I, Gritsch S, Perez E, Marx S, et al. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. Cell. 2021;184:1281-1298.e26 pubmed publisher
Dijkman K, Aguilo N, Boot C, Hofman S, Sombroek C, Vervenne R, et al. Pulmonary MTBVAC vaccination induces immune signatures previously correlated with prevention of tuberculosis infection. Cell Rep Med. 2021;2:100187 pubmed publisher
Vierboom M, Dijkman K, Sombroek C, Hofman S, Boot C, Vervenne R, et al. Stronger induction of trained immunity by mucosal BCG or MTBVAC vaccination compared to standard intradermal vaccination. Cell Rep Med. 2021;2:100185 pubmed publisher
Ma L, Gonzàlez Juncà A, Zheng Y, Ouyang H, Illa Bochaca I, Horst K, et al. Inflammation Mediates the Development of Aggressive Breast Cancer Following Radiotherapy. Clin Cancer Res. 2021;27:1778-1791 pubmed publisher
Yang R, Mele F, Worley L, Langlais D, Rosain J, Benhsaien I, et al. Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria. Cell. 2020;183:1826-1847.e31 pubmed publisher
Jenks J, Nelson C, Roark H, Goodwin M, Pass R, Bernstein D, et al. Antibody binding to native cytomegalovirus glycoprotein B predicts efficacy of the gB/MF59 vaccine in humans. Sci Transl Med. 2020;12: pubmed publisher
Frasca D, Diaz A, Romero M, Thaller S, Blomberg B. Secretion of autoimmune antibodies in the human subcutaneous adipose tissue. PLoS ONE. 2018;13:e0197472 pubmed publisher
Novakova L, Singh A, Axelsson M, Ståhlman M, Adiels M, Malmeström C, et al. Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing-remitting MS. J Neurochem. 2018;146:322-332 pubmed publisher

product information

Antigen :

IFN-gamma

Apps. Abbrev. :

ICFC

Cat # :

502540

Clone :

4S.B3

Item :

Brilliant Violet 711™ anti-human IFN-γ

Isotype :

Mouse IgG1, κ

Other Names :

Interferon-γ, Immune interferon, Type II interferon, T cell interferon, Macrophage-activating factor (MAF), IFN-g, IFN-gamma

Size :

100 tests

Price (USD) :

446 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

BV711

Immunogen :

Partially purified, native human IFN-γ

Application Notes :

ELISA or ELISPOT Detection^5: The biotinylated 4S.B3 antibody is useful as a detection antibody for a sandwich ELISA or ELISPOT assay, when used in conjunction with purified NIB42 antibody (Cat. No. 502402/502404) or purified MD-1 antibody (Cat. No. 507502/507513) as the capture antibody.Flow Cytometry^3,4,6-8: The fluorochrome-labeled 4S.B3 antibody is useful for intracellular immunofluorescent staining and flow cytometric analysis to identify IFN-γ -producing cells within mixed cell populations.Additional reported applications (for the relevant formats) include: neutralization^1,2, Western blotting, immunohistochemical staining of paraformaldehyde-fixed, saponin-treated tissue sections, and immunocytochemistry. The 4S.B3 antibody can neutralize the bioactivity of natural or recombinant IFN-γ.Note: For testing human IFN-γ in serum or plasma, BioLegend's ELISA Max™ Sets (Cat. No. 430101 to 430106) are specially developed and recommended.;

more info or order :

BioLegend product webpage