Brilliant Violet 421™ anti-human IL-10 | BioLegend 501421 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 421™ anti-human IL-10

catalog :

501421

quantity :

25 tests

price :

190 USD

clonality :

monoclonal

host :

rat

conjugate :

BV421

clone name :

JES3-9D7

reactivity :

human

application :

immunocytochemistry

more info or order :

BioLegend product webpage

citations: 9

Reference
Obasanmi G, Lois N, Armstrong D, Hombrebueno J, Lynch A, Chen M, et al. Peripheral Blood Mononuclear Cells from Patients with Type 1 Diabetes and Diabetic Retinopathy Produce Higher Levels of IL-17A, IL-10 and IL-6 and Lower Levels of IFN-γ-A Pilot Study. Cells. 2023;12: pubmed publisher
Volta V, Pérez Baos S, De La Parra C, Katsara O, Ernlund A, Dornbaum S, et al. A DAP5/eIF3d alternate mRNA translation mechanism promotes differentiation and immune suppression by human regulatory T cells. Nat Commun. 2021;12:6979 pubmed publisher
Arra A, Pech M, Fu H, Lingel H, Braun F, Beyer C, et al. Immune-checkpoint blockade of CTLA-4 (CD152) in antigen-specific human T-cell responses differs profoundly between neonates, children, and adults. Oncoimmunology. 2021;10:1938475 pubmed publisher
Wang S, Li M, Sun F, Chen C, Ye J, Li D, et al. Th17/Treg-cell balance in the peripheral blood of pregnant females with a history of recurrent spontaneous abortion receiving progesterone or cyclosporine A. Exp Ther Med. 2021;21:37 pubmed publisher
Li D, Bradley T, Cain D, Pedroza Pacheco I, Aggelakopoulou M, Parks R, et al. RAB11FIP5-Deficient Mice Exhibit Cytokine-Related Transcriptomic Signatures. Immunohorizons. 2020;4:713-728 pubmed publisher
Libera J, Wittner M, Kantowski M, Woost R, Eberhard J, de Heer J, et al. Decreased Frequency of Intestinal CD39+ γδ+ T Cells With Tissue-Resident Memory Phenotype in Inflammatory Bowel Disease. Front Immunol. 2020;11:567472 pubmed publisher
Weinstock N, Shin D, Dhimal N, Hong X, Irons E, Silvestri N, et al. Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction. Neuron. 2020;107:65-81.e9 pubmed publisher
BjÃ¶rkander S, Hell L, Johansson M, Forsberg M, Lasaviciute G, Roos S, et al. Staphylococcus aureus-derived factors induce IL-10, IFN-Î³ and IL-17A-expressing FOXP3+CD161+ T-helper cells in a partly monocyte-dependent manner. Sci Rep. 2016;6:22083 pubmed publisher
Stanisic D, Cutts J, Eriksson E, Fowkes F, Rosanas Urgell A, Siba P, et al. ?? T cells and CD14+ monocytes are predominant cellular sources of cytokines and chemokines associated with severe malaria. J Infect Dis. 2014;210:295-305 pubmed publisher

product information

Antigen :

IL-10

Apps. Abbrev. :

ICFC

Cat # :

501421

Clone :

JES3-9D7

Item :

Brilliant Violet 421™ anti-human IL-10

Isotype :

Rat IgG1, κ

Other Names :

Interleukin-10, B cell derived T cell growth factor (B-TCGF), Cytokine synthesis inhibitory factor (CSIF), T-cell growth inhibitory factor (TGIF)

Size :

25 tests

Price (USD) :

190 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BV421

Immunogen :

COS - expressed, recombinant human IL-10

Application Notes :

ELISA Capture^1-5 or ELISPOT Capture^6: The Ultra-LEAFpurified JES3-9D7 antibody is useful as the capture antibody in a sandwich ELISA, when used in conjunction with the biotinylated JES3-12G8 antibody (Cat. No. 501502) as the detecting antibody and recombinant human IL-10 (Cat. No. 571009) as the standard. The Ultra-LEAF™ purified antibody is suggested for ELISPOT capture.Neutralization^1-3,9: The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of human IL-10 bioactivity (Cat. Nos. 501427 & 501428). The JES3-9D7 antibody can neutralize the bioactivity of natural or recombinant IL-10.Additional reported applications (for the relevant formats) include: immunohistochemical staining^12.Note: For testing human IL-10 in serum or plasma, BioLegend's ELISA Max™ Sets (Cat. Nos. 430601 & 430606) are specially developed and recommended.The JES3-9D7 antibody reacts with human and viral interleukin-10 (IL-10).;

more info or order :

BioLegend product webpage