APC anti-human IL-10 | BioLegend 501409 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human IL-10

catalog :

501409

quantity :

25 tests

price :

113 USD

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

JES3-9D7

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 2c	Wei C, Mei J, Tang L, Liu Y, Li D, Li M, et al. 1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosis. Cell Death Dis. 2016;7:e2489 pubmed publisher
	Rice T, Diavatopoulos D, Guo Y, Donaldson B, Bouqueau M, Bosanquet A, et al. Modification of innate immune responses to Bordetella pertussis in babies from pertussis vaccinated pregnancies. EBioMedicine. 2021;72:103612 pubmed publisher
	Chang T, Niu C, Sun C, Ma Y, Guo R, Ruan Z, et al. Melatonin exerts immunoregulatory effects by balancing peripheral effector and regulatory T helper cells in myasthenia gravis. Aging (Albany NY). 2020;12:21147-21160 pubmed publisher
	Fenton T, Jørgensen P, Niss K, Rubin S, Mörbe U, Riis L, et al. Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity. Immunity. 2020;52:557-570.e6 pubmed publisher
	Roybal K, Williams J, Morsut L, Rupp L, Kolinko I, Choe J, et al. Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell. 2016;167:419-432.e16 pubmed publisher
	BjÃ¶rkander S, Hell L, Johansson M, Forsberg M, Lasaviciute G, Roos S, et al. Staphylococcus aureus-derived factors induce IL-10, IFN-Î³ and IL-17A-expressing FOXP3+CD161+ T-helper cells in a partly monocyte-dependent manner. Sci Rep. 2016;6:22083 pubmed publisher
	Smolders J, Peelen E, Thewissen M, Cohen Tervaert J, Menheere P, Hupperts R, et al. Safety and T cell modulating effects of high dose vitamin D3 supplementation in multiple sclerosis. PLoS ONE. 2010;5:e15235 pubmed publisher
	Bastien J, Krosl G, Therien C, Rashkovan M, Scotto C, Cohen S, et al. Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease. Blood. 2010;116:4859-69 pubmed publisher

product information

Antigen :

IL-10

Apps. Abbrev. :

ICFC

Cat # :

501409

Clone :

JES3-9D7

Item :

APC anti-human IL-10

Isotype :

Rat IgG1, κ

Other Names :

Interleukin-10, B cell derived T cell growth factor (B-TCGF), Cytokine synthesis inhibitory factor (CSIF), T-cell growth inhibitory factor (TGIF)

Size :

25 tests

Price (USD) :

113 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC

Immunogen :

COS - expressed, recombinant human IL-10

Application Notes :

ELISA Capture^1-5 or ELISPOT Capture^6: The Ultra-LEAFpurified JES3-9D7 antibody is useful as the capture antibody in a sandwich ELISA, when used in conjunction with the biotinylated JES3-12G8 antibody (Cat. No. 501502) as the detecting antibody and recombinant human IL-10 (Cat. No. 571009) as the standard. The Ultra-LEAF™ purified antibody is suggested for ELISPOT capture.Neutralization^1-3,9: The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of human IL-10 bioactivity (Cat. Nos. 501427 & 501428). The JES3-9D7 antibody can neutralize the bioactivity of natural or recombinant IL-10.Additional reported applications (for the relevant formats) include: immunohistochemical staining^12.Note: For testing human IL-10 in serum or plasma, BioLegend's ELISA Max™ Sets (Cat. Nos. 430601 & 430606) are specially developed and recommended.The JES3-9D7 antibody reacts with human and viral interleukin-10 (IL-10).;

more info or order :

BioLegend product webpage