PE anti-human IL-10 | BioLegend 501403 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human IL-10

catalog :

501403

quantity :

25 tests

price :

104 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

JES3-9D7

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 4a	Sayin I, Radtke A, Vella L, Jin W, Wherry E, Buggert M, et al. Spatial distribution and function of T follicular regulatory cells in human lymph nodes. J Exp Med. 2018;215:1531-1542 pubmed publisher
flow cytometry; human; fig 2	Pachnio A, Ciáurriz M, Begum J, Lal N, Zuo J, Beggs A, et al. Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium. PLoS Pathog. 2016;12:e1005832 pubmed publisher
	Gu C, Upchurch K, Horton J, Wiest M, Zurawski S, Millard M, et al. Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells. Front Immunol. 2021;12:678036 pubmed publisher
	Dijkman K, Aguilo N, Boot C, Hofman S, Sombroek C, Vervenne R, et al. Pulmonary MTBVAC vaccination induces immune signatures previously correlated with prevention of tuberculosis infection. Cell Rep Med. 2021;2:100187 pubmed publisher
	Stras S, Werner L, Toothaker J, Olaloye O, Oldham A, McCourt C, et al. Maturation of the Human Intestinal Immune System Occurs Early in Fetal Development. Dev Cell. 2019;51:357-373.e5 pubmed publisher
	Tripathi T, Yin W, Xue Y, Zurawski S, Fujita H, Hanabuchi S, et al. Central Roles of OX40L-OX40 Interaction in the Induction and Progression of Human T Cell-Driven Acute Graft-versus-Host Disease. Immunohorizons. 2019;3:110-120 pubmed publisher
	Guimarães F, Melo G, Cordeiro T, Feracin V, Vieira E, Pereira W, et al. T-lymphocyte-expressing inflammatory cytokines underlie persistence of proteinuria in children with idiopathic nephrotic syndrome. J Pediatr (Rio J). 2018;94:546-553 pubmed publisher
	Almeida V, Avelar Freitas B, Santos M, Costa L, Silva T, Pereira W, et al. Inhibitory effect of the Pseudobrickellia brasiliensis (Spreng) R.M. King & H. Rob. aqueous extract on human lymphocyte proliferation and IFN-? and TNF-? production in vitro. Braz J Med Biol Res. 2017;50:e5163 pubmed publisher
	Aravena O, Ferrier A, Menon M, Mauri C, Aguillon J, Soto L, et al. TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients. Arthritis Res Ther. 2017;19:8 pubmed publisher
	Lepse N, Abdulahad W, Rutgers A, Kallenberg C, Stegeman C, Heeringa P. Altered B cell balance, but unaffected B cell capacity to limit monocyte activation in anti-neutrophil cytoplasmic antibody-associated vasculitis in remission. Rheumatology (Oxford). 2014;53:1683-92 pubmed publisher
	McCarthy N, Bashir Z, Vossenkamper A, Hedin C, Giles E, Bhattacharjee S, et al. Proinflammatory V?2+ T cells populate the human intestinal mucosa and enhance IFN-? production by colonic ?? T cells. J Immunol. 2013;191:2752-63 pubmed publisher

product information

Antigen :

IL-10

Apps. Abbrev. :

ICFC

Cat # :

501403

Clone :

JES3-9D7

Item :

PE anti-human IL-10

Isotype :

Rat IgG1, κ

Other Names :

Interleukin-10, B cell derived T cell growth factor (B-TCGF), Cytokine synthesis inhibitory factor (CSIF), T-cell growth inhibitory factor (TGIF)

Size :

25 tests

Price (USD) :

104 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

COS - expressed, recombinant human IL-10

Application Notes :

ELISA Capture^1-5 or ELISPOT Capture^6: The Ultra-LEAFpurified JES3-9D7 antibody is useful as the capture antibody in a sandwich ELISA, when used in conjunction with the biotinylated JES3-12G8 antibody (Cat. No. 501502) as the detecting antibody and recombinant human IL-10 (Cat. No. 571009) as the standard. The Ultra-LEAF™ purified antibody is suggested for ELISPOT capture.Neutralization^1-3,9: The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of human IL-10 bioactivity (Cat. Nos. 501427 & 501428). The JES3-9D7 antibody can neutralize the bioactivity of natural or recombinant IL-10.Additional reported applications (for the relevant formats) include: immunohistochemical staining^12.Note: For testing human IL-10 in serum or plasma, BioLegend's ELISA Max™ Sets (Cat. Nos. 430601 & 430606) are specially developed and recommended.The JES3-9D7 antibody reacts with human and viral interleukin-10 (IL-10).;

more info or order :

BioLegend product webpage