product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Ultra-LEAF™ Purified anti-human IL-6
catalog :
501125
quantity :
100 μg
price :
182 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MQ2-13A5
reactivity :
human
application :
ELISA, immunocytochemistry, neutralization, mass cytometry
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • mass cytometry; human; loading ...; fig 4e
Ingelfinger F, Krishnarajah S, Kramer M, Utz S, Galli E, Lutz M, et al. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta Neuropathol. 2021;141:901-915 pubmed publisher
Donado C, Cao A, Simmons D, Croker B, Brennan P, Brenner M. A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling. Cell Rep. 2020;31:107466 pubmed publisher
Tyler C, McCarthy N, Lindsay J, Stagg A, Moser B, Eberl M. Antigen-Presenting Human γδ T Cells Promote Intestinal CD4+ T Cell Expression of IL-22 and Mucosal Release of Calprotectin. J Immunol. 2017;198:3417-3425 pubmed publisher
product information
Antigen :
IL-6
Apps. Abbrev. :
ELISA Capture, CyTOF®, ELISPOT Capture, Neut, ICFC
Cat # :
501125
Clone :
MQ2-13A5
Item :
Ultra-LEAF™ Purified anti-human IL-6
Isotype :
Rat IgG1, κ
Other Names :
Interleukin-6, B cell stimulating factor-2 (BSF-2), Cytotoxic T cell differentiation factor (CDF), Hepatocyte stimulating factor (HSF), Hybridoma/plasmacytoma growth factor (HPGF)
Size :
100 μg
Price (USD) :
182 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
ULEAF
Immunogen :
COS-7- expressed, recombinant human IL-6
Application Notes :
ELISA or ELISPOT Capture^1-3,7: The purified MQ2-13A5 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated MQ2-39C3 antibody (Cat. No. 501202) as the detecting antibody.Neutralization^1-3,5,6: The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of human IL-6 bioactivity (Cat. No. 501110). The MQ2-13A5 antibody can neutralize the bioactivity of natural or recombinant IL-6.Additional applications (for the relevant formats) include: intracellular flow cytometry^10.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA