Brilliant Violet 785™ anti-human IL-2 | BioLegend 500348 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 785™ anti-human IL-2

catalog :

500348

quantity :

100 tests

price :

446 USD

clonality :

monoclonal

host :

rat

conjugate :

Brilliant Violet 785

clone name :

MQ1-17H12

reactivity :

human, rhesus macaque

application :

immunocytochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; rhesus macaque; loading ...; fig 3a	Mylvaganam G, Rios D, Abdelaal H, Iyer S, Tharp G, Mavigner M, et al. Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection. Proc Natl Acad Sci U S A. 2017;114:1976-1981 pubmed publisher
flow cytometry; rhesus macaque; loading ...; tbl 1	Stanfield B, Pahar B, Chouljenko V, Veazey R, Kousoulas K. Vaccination of rhesus macaques with the live-attenuated HSV-1 vaccine VC2 stimulates the proliferation of mucosal T cells and germinal center responses resulting in sustained production of highly neutralizing antibodies. Vaccine. 2017;35:536-543 pubmed publisher
flow cytometry; human; loading ...	Wahid R, Fresnay S, Levine M, Sztein M. Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a. Clin Immunol. 2016;173:87-95 pubmed publisher
flow cytometry; human	Boer M, Prins C, van Meijgaarden K, van Dissel J, Ottenhoff T, Joosten S. Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults. Clin Vaccine Immunol. 2015;22:778-88 pubmed publisher
flow cytometry; human; loading ...; fig 4	Hebel K, Weinert S, Kuropka B, Knolle J, Kosak B, Jorch G, et al. CD4+ T cells from human neonates and infants are poised spontaneously to run a nonclassical IL-4 program. J Immunol. 2014;192:5160-70 pubmed publisher
	Gullà A, Morelli E, Samur M, Botta C, Hideshima T, Bianchi G, et al. Bortezomib induces anti-multiple myeloma immune response mediated by cGAS/STING pathway activation. Blood Cancer Discov. 2021;2:468-483 pubmed publisher
	Abd Hamid M, Yao X, Waugh C, Rosendo Machado S, Li C, Rostron T, et al. Defective Interferon Gamma Production by Tumor-Specific CD8+ T Cells Is Associated With 5'Methylcytosine-Guanine Hypermethylation of Interferon Gamma Promoter. Front Immunol. 2020;11:310 pubmed publisher
	Wu Z, Frascaroli G, Bayer C, Schmal T, Mertens T. Interleukin-2 from Adaptive T Cells Enhances Natural Killer Cell Activity against Human Cytomegalovirus-Infected Macrophages. J Virol. 2015;89:6435-41 pubmed publisher
	Arya S, Park M. 4-Fluoro-3-nitrophenyl grafted gold electrode based platform for label free electrochemical detection of interleukin-2 protein. Biosens Bioelectron. 2014;61:260-5 pubmed publisher
	Colleton B, Huang X, Melhem N, Fan Z, Borowski L, Rappocciolo G, et al. Primary human immunodeficiency virus type 1-specific CD8+ T-cell responses induced by myeloid dendritic cells. J Virol. 2009;83:6288-99 pubmed publisher
	Dzhagalov I, Chambon P, He Y. Regulation of CD8+ T lymphocyte effector function and macrophage inflammatory cytokine production by retinoic acid receptor gamma. J Immunol. 2007;178:2113-21 pubmed

product information

Antigen :

IL-2

Apps. Abbrev. :

ICFC

Cat # :

500348

Clone :

MQ1-17H12

Item :

Brilliant Violet 785™ anti-human IL-2

Isotype :

Rat IgG2a, κ

Other Names :

Interleukin-2, T cell growth factor (TCGF), Eosinophil differentiation factor (EDF), Killer cell helper factor (KHF), Macrophage-activating factor for cytotoxicity I (MAF-C I), Thymocyte differentiation factor (TDF)

Size :

100 tests

Price (USD) :

446 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BV785

Immunogen :

E. coli - expressed recombinant human IL-2

Application Notes :

ELISA or ELISPOT Capture^2,3: The purified MQ1-17H12 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the Biotin anti-human IL-2 antibody (Cat. No. 517605) as the detecting antibody. The Ultra-LEAF™ purified antibody is suggested for ELISPOT capture. For ELISPOT capture applications, a concentration range of 4.0 - 8.0 µg/mL is recommended.Additional reported applications (for the relevant formats) include: immunoprecipitation^2, immunohistochemical staining of paraformaldehyde-fixed, saponin-treated frozen tissue sections^1,4-6,8, neutralization^13, and immunocytochemistry.Note: For testing human IL-2 in serum or plasma, BioLegend's LEGEND MAX™ Kit (Cat. No. 431807) is specially developed and recommended.Clone MQ1-17H12 cross-reacts to Cat^15;

more info or order :

BioLegend product webpage