product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC/Cyanine7 anti-mouse IgD
catalog :
405716
quantity :
100 μg
price :
323 USD
clonality :
monoclonal
host :
rat
conjugate :
APC/Cy7
clone name :
11-26c.2a
reactivity :
mouse, rat
application :
flow cytometry
more info or order :
citations: 45
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 3a
Yang Y, Li X, Ma Z, Wang C, Yang Q, Byrne Steele M, et al. CTLA-4 expression by B-1a B cells is essential for immune tolerance. Nat Commun. 2021;12:525 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2c
Webster P, Dawes J, Dewchand H, Takacs K, Iadarola B, Bolt B, et al. Subclonal mutation selection in mouse lymphomagenesis identifies known cancer loci and suggests novel candidates. Nat Commun. 2018;9:2649 pubmed publisher
  • flow cytometry; mouse; fig 1a
Xiao G, Chan L, Klemm L, Braas D, Chen Z, Geng H, et al. B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. Cell. 2018;173:470-484.e18 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Xue D, Desjardins M, Kaufman G, Beland M, Al Tamemi S, Ahmed E, et al. Semaphorin 4C: A Novel Component of B-Cell Polarization in Th2-Driven Immune Responses. Front Immunol. 2016;7:558 pubmed publisher
  • flow cytometry; mouse
Jones D, Wilmore J, Allman D. Cellular Dynamics of Memory B Cell Populations: IgM+ and IgG+ Memory B Cells Persist Indefinitely as Quiescent Cells. J Immunol. 2015;195:4753-9 pubmed publisher
Ludwig J, Scally S, Costa G, Hoffmann S, Murugan R, Lossin J, et al. Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model. NPJ Vaccines. 2023;8:52 pubmed publisher
Ke F, Benet Z, Maz M, Liu J, Dent A, KAHLENBERG J, et al. Germinal center B cells that acquire nuclear proteins are specifically suppressed by follicular regulatory T cells. elife. 2023;12: pubmed publisher
Geng T, Wang P. Quantitative Analysis of B-Cell Subpopulations in Bone Marrow by Flow Cytometry. Methods Mol Biol. 2023;2585:71-77 pubmed publisher
Hodgson R, Xu X, Anzilotti C, Deobagkar Lele M, Crockford T, Kepple J, et al. NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance. Commun Biol. 2022;5:1216 pubmed publisher
Tas J, Koo J, Lin Y, Xie Z, Steichen J, Jackson A, et al. Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses. Immunity. 2022;55:1856-1871.e6 pubmed publisher
Hu Q, Xu T, Zhang M, Zhang H, Liu Y, Li H, et al. Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response. Cell Rep. 2022;40:111035 pubmed publisher
Wilmore J, Gaudette B, G xf3 mez Atria D, Rosenthal R, Reiser S, Meng W, et al. IgA Plasma Cells Are Long-Lived Residents of Gut and Bone Marrow That Express Isotype- and Tissue-Specific Gene Expression Patterns. Front Immunol. 2021;12:791095 pubmed publisher
Alameh M, Tombácz I, Bettini E, Lederer K, Sittplangkoon C, Wilmore J, et al. Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses. Immunity. 2021;54:2877-2892.e7 pubmed publisher
Burnett D, Jackson K, Langley D, Aggrawal A, Stella A, Johansen M, et al. Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability. Immunity. 2021;54:2908-2921.e6 pubmed publisher
Niemeyer B, Sanford B, Gibson J, Berger J, Oko L, Medina E, et al. The gammaherpesvirus 68 viral cyclin facilitates expression of LANA. PLoS Pathog. 2021;17:e1010019 pubmed publisher
Schardt J, Pornnoppadol G, Desai A, Park K, Zupancic J, Makowski E, et al. Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening. Sci Rep. 2021;11:20738 pubmed publisher
Nanou A, Bourbouli M, Vetrano S, Schaeper U, Ley S, Kollias G. Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis. Cell Rep. 2021;35:109168 pubmed publisher
Zhang H, Dai D, Hu Q, Yang F, Xue Y, Li F, et al. Bach2 attenuates IL-2R signaling to control Treg homeostasis and Tfr development. Cell Rep. 2021;35:109096 pubmed publisher
Mandal R, Denny J, Namazzi R, Opoka R, Datta D, John C, et al. Dynamic modulation of spleen germinal center reactions by gut bacteria during Plasmodium infection. Cell Rep. 2021;35:109094 pubmed publisher
Prados A, Onder L, Cheng H, Mörbe U, Lütge M, Gil Cruz C, et al. Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity. Nat Immunol. 2021;22:510-519 pubmed publisher
Lazarian G, Yin S, ten Hacken E, Sewastianik T, Uduman M, Font Tello A, et al. A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation. Cancer Cell. 2021;39:380-393.e8 pubmed publisher
Suah A, Tran D, Khiew S, Andrade M, Pollard J, Jain D, et al. Pregnancy-induced humoral sensitization overrides T cell tolerance to fetus-matched allografts in mice. J Clin Invest. 2021;131: pubmed publisher
Waide M, Polidoro R, Powell W, Denny J, Kos J, Tieri D, et al. Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections. Cell Rep. 2020;33:108503 pubmed publisher
Laczkó D, Hogan M, Toulmin S, Hicks P, Lederer K, Gaudette B, et al. A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice. Immunity. 2020;53:724-732.e7 pubmed publisher
Khiew S, Jain D, Chen J, Yang J, Yin D, Young J, et al. Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells. J Clin Invest. 2020;130:3453-3466 pubmed publisher
Fallet B, Hao Y, Florova M, Cornille K, de Los Aires A, Girelli Zubani G, et al. Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses. Cell Rep. 2020;30:1013-1026.e7 pubmed publisher
Shehata L, Maurer D, Wec A, Lilov A, Champney E, Sun T, et al. Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability. Cell Rep. 2019;28:3300-3308.e4 pubmed publisher
Zhang H, Alsaleh G, Feltham J, Sun Y, Napolitano G, Riffelmacher T, et al. Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. Mol Cell. 2019;76:110-125.e9 pubmed publisher
Turner J, Ke F, GRIGOROVA I. B Cell Receptor Crosslinking Augments Germinal Center B Cell Selection when T Cell Help Is Limiting. Cell Rep. 2018;25:1395-1403.e4 pubmed publisher
Shan M, Carrillo J, Yeste A, Gutzeit C, Segura Garzón D, Walland A, et al. Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44. Immunity. 2018;49:709-724.e8 pubmed publisher
Ghezraoui H, Oliveira C, Becker J, Bilham K, Moralli D, Anzilotti C, et al. 53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ. Nature. 2018;560:122-127 pubmed publisher
Wilmore J, Gaudette B, Gomez Atria D, Hashemi T, Jones D, Gardner C, et al. Commensal Microbes Induce Serum IgA Responses that Protect against Polymicrobial Sepsis. Cell Host Microbe. 2018;23:302-311.e3 pubmed publisher
Scally S, McLeod B, Bosch A, Miura K, Liang Q, Carroll S, et al. Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun. 2017;8:1568 pubmed publisher
Turner J, Benet Z, Grigorova I. Antigen Acquisition Enables Newly Arriving B Cells To Enter Ongoing Immunization-Induced Germinal Centers. J Immunol. 2017;199:1301-1307 pubmed publisher
Sebina I, James K, Soon M, Fogg L, Best S, Labastida Rivera F, et al. IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection. PLoS Pathog. 2016;12:e1005999 pubmed publisher
Kurkewich J, Klopfenstein N, Hallas W, Wood C, Sattler R, Das C, et al. Arid3b Is Critical for B Lymphocyte Development. PLoS ONE. 2016;11:e0161468 pubmed publisher
Proudhon C, Snetkova V, Raviram R, Lobry C, Badri S, Jiang T, et al. Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation. Cell Rep. 2016;15:2159-2169 pubmed publisher
Palmer V, Aziz Seible R, Kassmeier M, Rothermund M, Perry G, Swanson P. VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection. J Immunol. 2015;195:1524-37 pubmed publisher
Reynolds A, Kuraoka M, Kelsoe G. Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. J Immunol. 2015;194:231-42 pubmed publisher
Rouaud P, Saintamand A, Saad F, Carrion C, Lecardeur S, Cogne M, et al. Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region. J Exp Med. 2014;211:975-85 pubmed publisher
Saumyaa -, Arjunaraja S, Pujanauski L, Colino J, Torres R, Snapper C. Immunosuppressive property within the Streptococcus pneumoniae cell wall that inhibits generation of T follicular helper, germinal center, and plasma cell response to a coimmunized heterologous protein. Infect Immun. 2013;81:3426-33 pubmed publisher
Park S, Wolfram P, Canty K, Harley B, Nombela Arrieta C, Pivarnik G, et al. Focal adhesion kinase regulates the localization and retention of pro-B cells in bone marrow microenvironments. J Immunol. 2013;190:1094-102 pubmed publisher
Tomayko M, Steinel N, Anderson S, Shlomchik M. Cutting edge: Hierarchy of maturity of murine memory B cell subsets. J Immunol. 2010;185:7146-50 pubmed publisher
Good Jacobson K, Szumilas C, Chen L, Sharpe A, Tomayko M, Shlomchik M. PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells. Nat Immunol. 2010;11:535-42 pubmed publisher
Ahuja A, Shupe J, Dunn R, Kashgarian M, Kehry M, Shlomchik M. Depletion of B cells in murine lupus: efficacy and resistance. J Immunol. 2007;179:3351-61 pubmed
product information
Antigen :
IgD
Apps. Abbrev. :
FC
Cat # :
405716
Clone :
11-26c.2a
Item :
APC/Cyanine7 anti-mouse IgD
Isotype :
Rat IgG2a, κ
Other Names :
Immunoglobulin D
Size :
100 μg
Price (USD) :
323 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC_CYANINE7
Application Notes :
The 11-26c.2a antibody reacts with immunoglobulin D in all tested mouse haplotypes. The antibody binds membrane IgD expressed on most B cells. The 11-26c.2a antibody neither induces proliferation of splenic B cells nor induces B cell activation. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections^2,3, and spatial biology (IBEX)^10,11.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA