product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PerCP/Cyanine5.5 anti-mouse IgD
catalog :
405709
quantity :
25 μg
price :
141 USD
clonality :
monoclonal
host :
rat
conjugate :
PerCP/Cy5.5
clone name :
11-26c.2a
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 41
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 1b
Graf R, Seagal J, Otipoby K, Lam K, Ayoub S, Zhang B, et al. BCR-dependent lineage plasticity in mature B cells. Science. 2019;363:748-753 pubmed publisher
  • flow cytometry; mouse; fig s4
Yang Y, Xu J, Chen H, Fei X, Tang Y, Yan Y, et al. MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells. Oncotarget. 2016;7:17520-31 pubmed publisher
Knudsen M, Agrawal P, MacCamy A, Parks K, Gray M, Takushi B, et al. Adjuvants influence the maturation of VRC01-like antibodies during immunization. iScience. 2022;25:105473 pubmed publisher
Knizkova D, Pribikova M, Draberova H, Semberova T, Trivic T, Synackova A, et al. CMTM4 is a subunit of the IL-17 receptor and mediates autoimmune pathology. Nat Immunol. 2022;23:1644-1652 pubmed publisher
Hutter K, R xfc licke T, Szabó T, Andersen L, Villunger A, Herzog S. The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression. Front Immunol. 2022;13:967914 pubmed publisher
Zhu Y, Gu H, Yang L, Li N, Chen Q, Kang D, et al. Involvement of MST1/mTORC1/STAT1 activity in the regulation of B-cell receptor signalling by chemokine receptor 2. Clin Transl Med. 2022;12:e887 pubmed publisher
Torres Ruiz J, Pérez Fragoso A, Maravillas Montero J, Llorente L, Mejía Domínguez N, Páez Franco J, et al. Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes. Front Immunol. 2021;12:689966 pubmed publisher
Duan L, Liu D, Chen H, Mintz M, Chou M, Kotov D, et al. Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation. Immunity. 2021;54:2256-2272.e6 pubmed publisher
Monz xf3 n Casanova E, Bates K, Smith C, Turner M. Essential requirement for polypyrimidine tract binding proteins 1 and 3 in the maturation and maintenance of mature B cells in mice. Eur J Immunol. 2021;51:2266-2273 pubmed publisher
Miyauchi K, Adachi Y, Tonouchi K, Yajima T, Harada Y, Fukuyama H, et al. Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells. Nat Commun. 2021;12:3789 pubmed publisher
Chauveau L, Bridgeman A, Tan T, Beveridge R, Frost J, Rijal P, et al. Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity. EMBO Rep. 2021;22:e52447 pubmed publisher
Yang L, Li N, Yang D, Chen A, Tang J, Jing Y, et al. CCL2 regulation of MST1-mTOR-STAT1 signaling axis controls BCR signaling and B-cell differentiation. Cell Death Differ. 2021;: pubmed publisher
Frost J, Tan T, Abbas M, Wideman S, Bonadonna M, Stoffel N, et al. Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection. Med. 2021;2:164-179.e12 pubmed publisher
Huang D, Tran J, Olson A, Vollbrecht T, Tenuta M, Guryleva M, et al. Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells. Nat Commun. 2020;11:5850 pubmed publisher
Haniuda K, Fukao S, Kitamura D. Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling. Cell Rep. 2020;33:108333 pubmed publisher
Lin Y, Parks K, Weidle C, Naidu A, Khechaduri A, Riker A, et al. HIV-1 VRC01 Germline-Targeting Immunogens Select Distinct Epitope-Specific B Cell Receptors. Immunity. 2020;53:840-851.e6 pubmed publisher
Du Z, Chen A, Huang L, Dai X, Chen Q, Yang D, et al. STAT3 couples with 14-3-3σ to regulate BCR signaling, B-cell differentiation, and IgE production. J Allergy Clin Immunol. 2021;147:1907-1923.e6 pubmed publisher
Wong R, Belk J, Govero J, Uhrlaub J, Reinartz D, Zhao H, et al. Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses. Immunity. 2020;53:1078-1094.e7 pubmed publisher
Bartleson J, Viehmann Milam A, Donermeyer D, Horvath S, Xia Y, Egawa T, et al. Strength of tonic T cell receptor signaling instructs T follicular helper cell-fate decisions. Nat Immunol. 2020;21:1384-1396 pubmed publisher
Hutter K, Rülicke T, Drach M, Andersen L, Villunger A, Herzog S. Differential roles of miR-15a/16-1 and miR-497/195 clusters in immune cell development and homeostasis. FEBS J. 2021;288:1533-1545 pubmed publisher
Guilbert C, Chou H, Bolt A, Wu T, Luo V, Orthwein A, et al. A Functional Assay to Assess Toxicity During Murine B Cell Development In Vitro. Curr Protoc Toxicol. 2020;83:e91 pubmed publisher
Parks K, MacCamy A, Trichka J, Gray M, Weidle C, Borst A, et al. Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization. Cell Rep. 2019;29:3060-3072.e7 pubmed publisher
Viny A, Bowman R, Liu Y, Lavallée V, Eisman S, Xiao W, et al. Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation. Cell Stem Cell. 2019;25:682-696.e8 pubmed publisher
Jing Y, Kang D, Liu L, Huang H, Chen A, Yang L, et al. Dedicator of cytokinesis protein 2 couples with lymphoid enhancer-binding factor 1 to regulate expression of CD21 and B-cell differentiation. J Allergy Clin Immunol. 2019;: pubmed publisher
Komban R, Strömberg A, Biram A, Cervin J, Lebrero Fernández C, Mabbott N, et al. Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome. Nat Commun. 2019;10:2423 pubmed publisher
Yin S, Gambe R, Sun J, Martinez A, Cartun Z, Regis F, et al. A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion. Cancer Cell. 2019;35:283-296.e5 pubmed publisher
Cantor D, King B, Blumenberg L, Dimauro T, Aifantis I, Koralov S, et al. Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice. Cell Rep. 2019;26:108-118.e4 pubmed publisher
Turner J, Ke F, GRIGOROVA I. B Cell Receptor Crosslinking Augments Germinal Center B Cell Selection when T Cell Help Is Limiting. Cell Rep. 2018;25:1395-1403.e4 pubmed publisher
Stewart I, Radtke D, Phillips B, McGowan S, Bannard O. Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging. Immunity. 2018;49:477-489.e7 pubmed publisher
Prüss H, Tedeschi A, Thiriot A, Lynch L, Loughhead S, Stutte S, et al. Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex. Nat Neurosci. 2017;20:1549-1559 pubmed publisher
Sabouri Z, Perotti S, Spierings E, Humburg P, Yabas M, Bergmann H, et al. IgD attenuates the IgM-induced anergy response in transitional and mature B cells. Nat Commun. 2016;7:13381 pubmed publisher
Di Marco Barros R, Roberts N, Dart R, Vantourout P, Jandke A, Nussbaumer O, et al. Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments. Cell. 2016;167:203-218.e17 pubmed publisher
Bemark M, Hazanov H, Strömberg A, Komban R, Holmqvist J, Köster S, et al. Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization. Nat Commun. 2016;7:12698 pubmed publisher
Na B, Kwon M, Chae M, Kim H, Kim C, Jun C, et al. Transgelin-2 in B-Cells Controls T-Cell Activation by Stabilizing T Cell - B Cell Conjugates. PLoS ONE. 2016;11:e0156429 pubmed publisher
He Z, O Neal J, Wilson W, Mahajan N, Luo J, Wang Y, et al. Deletion of Rb1 induces both hyperproliferation and cell death in murine germinal center B cells. Exp Hematol. 2016;44:161-5.e4 pubmed publisher
Rouaud P, Saintamand A, Saad F, Carrion C, Lecardeur S, Cogne M, et al. Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region. J Exp Med. 2014;211:975-85 pubmed publisher
Park S, Wolfram P, Canty K, Harley B, Nombela Arrieta C, Pivarnik G, et al. Focal adhesion kinase regulates the localization and retention of pro-B cells in bone marrow microenvironments. J Immunol. 2013;190:1094-102 pubmed publisher
Kelly A, Lemaire M, Young Y, Eustache J, Guilbert C, Molina M, et al. In vivo tungsten exposure alters B-cell development and increases DNA damage in murine bone marrow. Toxicol Sci. 2013;131:434-46 pubmed publisher
Tomayko M, Steinel N, Anderson S, Shlomchik M. Cutting edge: Hierarchy of maturity of murine memory B cell subsets. J Immunol. 2010;185:7146-50 pubmed publisher
Good Jacobson K, Szumilas C, Chen L, Sharpe A, Tomayko M, Shlomchik M. PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells. Nat Immunol. 2010;11:535-42 pubmed publisher
Ahuja A, Shupe J, Dunn R, Kashgarian M, Kehry M, Shlomchik M. Depletion of B cells in murine lupus: efficacy and resistance. J Immunol. 2007;179:3351-61 pubmed
product information
Antigen :
IgD
Apps. Abbrev. :
FC
Cat # :
405709
Clone :
11-26c.2a
Item :
PerCP/Cyanine5.5 anti-mouse IgD
Isotype :
Rat IgG2a, κ
Other Names :
Immunoglobulin D
Size :
25 μg
Price (USD) :
141 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PERCP_CYANINE5.5
Application Notes :
The 11-26c.2a antibody reacts with immunoglobulin D in all tested mouse haplotypes. The antibody binds membrane IgD expressed on most B cells. The 11-26c.2a antibody neither induces proliferation of splenic B cells nor induces B cell activation. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections^2,3, and spatial biology (IBEX)^10,11.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA