product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
secondary antibody
product name :
Ultra-LEAF™ Purified Human IgG4 Isotype Ctrl Recombinant
catalog :
403701
quantity :
100 μg
price :
248 USD
more info or order :
citations: 13
Reference
Lee H, Hwang M, Jang S, Um S. Immune Regulatory Function of Cancer- Associated Fibroblasts in Non-small Cell Lung Cancer. Tuberc Respir Dis (Seoul). 2023;86:304-318 pubmed publisher
Balasko A, Kowatsch M, Graydon C, Lajoie J, Fowke K. The effect of blocking immune checkpoints LAG-3 and PD-1 on human invariant Natural Killer T cell function. Sci Rep. 2023;13:10082 pubmed publisher
Mandel I, Haves Ziv D, Goldshtein I, Peretz T, Alishekevitz D, Fridman Dror A, et al. BND-22, a first-in-class humanized ILT2-blocking antibody, promotes antitumor immunity and tumor regression. J Immunother Cancer. 2022;10: pubmed publisher
Takele Y, Adem E, Franssen S, Womersley R, Kaforou M, Levin M, et al. Impaired in vitro Interferon-γ production in patients with visceral leishmaniasis is improved by inhibition of PD1/PDL-1 ligation. PLoS Negl Trop Dis. 2022;16:e0010544 pubmed publisher
Thakkar D, Paliwal S, Dharmadhikari B, Guan S, Liu L, Kar S, et al. Rationally targeted anti-VISTA antibody that blockades the C-C' loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit tumor growth in an Fc independent manner. J Immunother Cancer. 2022;10: pubmed publisher
Assi H, Wong C, Tipton K, Mei L, Wong K, Razo J, et al. Conditional PD-1/PD-L1 Probody Therapeutics Induce Comparable Antitumor Immunity but Reduced Systemic Toxicity Compared with Traditional Anti-PD-1/PD-L1 Agents. Cancer Immunol Res. 2021;9:1451-1464 pubmed publisher
Phakham T, Bulaon C, Khorattanakulchai N, Shanmugaraj B, Buranapraditkun S, Boonkrai C, et al. Functional Characterization of Pembrolizumab Produced in Nicotiana benthamiana Using a Rapid Transient Expression System. Front Plant Sci. 2021;12:736299 pubmed publisher
Tahir S, Bourquard T, Musnier A, Jullian Y, Corde Y, Omahdi Z, et al. Accurate determination of epitope for antibodies with unknown 3D structures. MAbs. 2021;13:1961349 pubmed publisher
Junker F, Gulati P, Wessels U, Seeber S, Stubenrauch K, Codarri Deak L, et al. A human receptor occupancy assay to measure anti-PD-1 binding in patients with prior anti-PD-1. Cytometry A. 2021;99:832-843 pubmed publisher
Roberts A, Bentley L, Tang T, Stewart F, Pallini C, Juvvanapudi J, et al. Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation. Sci Rep. 2021;11:4030 pubmed publisher
Fassler M, Rappaport M, Cuño C, George J. Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer's disease models. J Neuroinflammation. 2021;18:19 pubmed publisher
Smalley M, Przedborski M, Thiyagarajan S, Pellowe M, Verma A, Brijwani N, et al. Integrating Systems Biology and an Ex Vivo Human Tumor Model Elucidates PD-1 Blockade Response Dynamics. iScience. 2020;23:101229 pubmed publisher
Sasaki T, Yajima T, Shimaoka T, Ogawa S, Saito T, Yamaoka K, et al. Synergistic effect of IgG4 antibody and CTLs causes tissue inflammation in IgG4-related disease. Int Immunol. 2020;32:163-174 pubmed publisher
product information
Apps. Abbrev. :
FC
Cat # :
403701
Clone :
QA16A15
Item :
Ultra-LEAF™ Purified Human IgG4 Isotype Ctrl Recombinant
Isotype :
Human IgG4, κ
Other Names :
IGHG4, immunoglobulin heavy chain constant region gamma 4
Size :
100 μg
Price (USD) :
248 USD
Clonality :
Recombinant
Host :
Human
Conjugate/Tag/Label :
ULEAF
Application Notes :
QA16A15 is a recombinant human IgG4. It can be used as an isotype control when evaluating fully human, humanized, or chimeric antibodies. This product is suitable as an isotype-matched control for ELISA, immunoblotting, FACS, IHC, and functional studies.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA