APC Rat IgG1, κ isotype Ctrl | BioLegend 400412 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC Rat IgG1, κ isotype Ctrl

catalog :

400412

quantity :

100 μg

price :

94 USD

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

RTK2071

application :

flow cytometry

citations: 10

Reference
De Vlaminck K, Romão E, Puttemans J, Pombo Antunes A, Kancheva D, Scheyltjens I, et al. Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha. Front Immunol. 2021;12:777524 pubmed publisher
Molina M, Hoffman E, Stokes J, Kummet N, Smith K, Baker F, et al. Regulatory Dendritic Cells Induced by Bendamustine Are Associated With Enhanced Flt3 Expression and Alloreactive T-Cell Death. Front Immunol. 2021;12:699128 pubmed publisher
Dai X, Bu X, Gao Y, Guo J, Hu J, Jiang C, et al. Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade. Mol Cell. 2021;81:2317-2331.e6 pubmed publisher
Ni J, Wang X, Stojanovic A, Zhang Q, Wincher M, Bühler L, et al. Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity. Immunity. 2020;52:1075-1087.e8 pubmed publisher
Hegde S, Krisnawan V, Herzog B, Zuo C, Breden M, Knolhoff B, et al. Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer. Cancer Cell. 2020;37:289-307.e9 pubmed publisher
Niemann J, Woller N, Brooks J, Fleischmann Mundt B, Martin N, Kloos A, et al. Molecular retargeting of antibodies converts immune defense against oncolytic viruses into cancer immunotherapy. Nat Commun. 2019;10:3236 pubmed publisher
Choi H, Deng J, Li S, Silk T, Dong L, Brea E, et al. Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer. Cell Rep. 2019;27:806-819.e5 pubmed publisher
Martínez López M, Iborra S, Conde Garrosa R, Mastrangelo A, Danne C, Mann E, et al. Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity. Immunity. 2019;50:446-461.e9 pubmed publisher
Santos R, Vadodaria K, Jaeger B, Mei A, Lefcochilos Fogelquist S, Mendes A, et al. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells. Stem Cell Reports. 2017;8:1757-1769 pubmed publisher
Periasamy S, Porter K, Atianand M, T Le H, Earley S, Duffy E, et al. Pyrin-only protein 2 limits inflammation but improves protection against bacteria. Nat Commun. 2017;8:15564 pubmed publisher

product information

Apps. Abbrev. :

Flow Cytometry, Intracellular Staining for Flow Cytometry

Cat # :

400412

Clone :

RTK2071

Item :

APC Rat IgG1, κ isotype Ctrl

Isotype :

Rat IgG1, κ

Size :

100 μg

Price (USD) :

94 USD

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC

Immunogen :

Trinitrophenol + KLH

Application Notes :

The RTK2071 immunoglobulin is useful as an isotype-matched control (for the relevant formats) for Western blotting, immunoprecipitation, immunohistochemistry, functional assay, and immunofluorescence microscopy. The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 400414) as negative control 1 . For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 400432) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).