product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE Mouse IgG1, κ Isotype Ctrl
catalog :
400112
quantity :
100 μg
price :
77 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
MOPC-21
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 102
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...
Marozin S, Simon Nobbe B, Irausek S, Chung L, Lepperdinger G. Kinship of conditionally immortalized cells derived from fetal bone to human bone-derived mesenchymal stroma cells. Sci Rep. 2021;11:10933 pubmed publisher
  • flow cytometry; human; loading ...; fig 1
Krogh Nielsen M, Hector S, Allen K, Subhi Y, Sørensen T. Altered activation state of circulating neutrophils in patients with neovascular age-related macular degeneration. Immun Ageing. 2017;14:18 pubmed publisher
  • flow cytometry; human; 1:50
Lokmic Z, Ng E, Burton M, Stanley E, Penington A, Elefanty A. Isolation of human lymphatic endothelial cells by multi-parameter fluorescence-activated cell sorting. J Vis Exp. 2015;:e52691 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Kimura Y, van der Merwe M, Bering S, Penmatsa H, Conoley V, Sangild P, et al. Glucose transport by epithelia prepared from harvested enterocytes. Cytotechnology. 2015;67:39-49 pubmed publisher
Yen F, Glusac J, Levi S, Zernov A, Baruch L, Davidovich Pinhas M, et al. Cultured meat platform developed through the structuring of edible microcarrier-derived microtissues with oleogel-based fat substitute. Nat Commun. 2023;14:2942 pubmed publisher
Jacquot P, Mu xf1 oz Garcia J, Fleury M, Cochonneau D, Gaussin R, Enouf E, et al. Engineering of a Bispecific Nanofitin with Immune Checkpoint Inhibitory Activity Conditioned by the Cross-Arm Binding to EGFR and PDL1. Biomolecules. 2023;13: pubmed publisher
Hu X, White K, Olroyd A, Dejesus R, Dominguez A, Dowdle W, et al. Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques. Nat Biotechnol. 2023;: pubmed publisher
Ciftci E, Bozbeyoglu N, Gursel I, Korkusuz F, Bakan Misirlioglu F, Korkusuz P. Comparative analysis of magnetically activated cell sorting and ultracentrifugation methods for exosome isolation. PLoS ONE. 2023;18:e0282238 pubmed publisher
Vondra S, H xf6 bler A, Lackner A, Raffetseder J, Mihalic Z, Vogel A, et al. The human placenta shapes the phenotype of decidual macrophages. Cell Rep. 2023;42:111977 pubmed publisher
Iancu O, Allen D, Knop O, Zehavi Y, Breier D, Arbiv A, et al. Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs. Mol Ther Nucleic Acids. 2023;31:105-121 pubmed publisher
Gerace D, Zhou Q, Kenty J, Veres A, Sintov E, Wang X, et al. Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance. Cell Rep Med. 2023;4:100879 pubmed publisher
Jo S, Lee S, Park J, Nam B, Kim H, Youn J, et al. Platelet-Derived Growth Factor B Is a Key Element in the Pathological Bone Formation of Ankylosing Spondylitis. J Bone Miner Res. 2023;38:300-312 pubmed publisher
Cano Mendez A, Garc xed a Larragoiti N, Damian Vazquez M, Guzman Cancino P, Lopez Castaneda S, Ochoa Zarzosa A, et al. Platelet Reactivity and Inflammatory Phenotype Induced by Full-Length Spike SARS-CoV-2 Protein and Its RBD Domain. Int J Mol Sci. 2022;23: pubmed publisher
Cao B, Liu M, Wang L, Zhu K, Cai M, Chen X, et al. Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer. Nat Commun. 2022;13:6203 pubmed publisher
Silva A, Rodrigues C, Ferreira I, Santos L, Santos D, Ara xfa jo T, et al. A Novel Detection Method of Breast Cancer through a Simple Panel of Biomarkers. Int J Mol Sci. 2022;23: pubmed publisher
Kitagawa S, Matsuda T, Washizaki A, Murakami H, Yamamoto T, Yoshioka Y. Elucidation of the role of nucleolin as a cell surface receptor for nucleic acid-based adjuvants. NPJ Vaccines. 2022;7:115 pubmed publisher
Hopf A, Al Bayati L, Schaefer D, Kalbermatten D, Guzman R, Madduri S. Optimized Decellularization Protocol for Large Peripheral Nerve Segments: Towards Personalized Nerve Bioengineering. Bioengineering (Basel). 2022;9: pubmed publisher
Hofmann L, Medyany V, Ezi x107 J, Lotfi R, Niesler B, R xf6 th R, et al. Cargo and Functional Profile of Saliva-Derived Exosomes Reveal Biomarkers Specific for Head and Neck Cancer. Front Med (Lausanne). 2022;9:904295 pubmed publisher
Sharari S, Aouida M, Mohammed I, Haris B, Bhat A, Hawari I, et al. Understanding the Mechanism of Dysglycemia in a Fanconi-Bickel Syndrome Patient. Front Endocrinol (Lausanne). 2022;13:841788 pubmed publisher
Kuczynski E, Morlino G, Peter A, Coenen Stass A, Moss J, Wali N, et al. A preclinical model of peripheral T-cell lymphoma GATA3 reveals DNA damage response pathway vulnerability. EMBO Mol Med. 2022;14:e15816 pubmed publisher
Connor T, Sleebs N, Lokmic Tomkins Z. Multiparameter Fluorescence-Activated Cell Sorting of Human Lymphatic Endothelial Cells. Methods Mol Biol. 2022;2475:47-59 pubmed publisher
Shimizu S, Shiraki A. CRISPR/Cas9 unveils the dynamics of the endogenous µ-opioid receptors on neuronal cells under continuous opioid stimulation. Pharmacol Res Perspect. 2022;10:e00933 pubmed publisher
Figueroa Romero C, Monteagudo A, Murdock B, Famie J, Webber Davis I, Piecuch C, et al. Tofacitinib Suppresses Natural Killer Cells In Vitro and In Vivo: Implications for Amyotrophic Lateral Sclerosis. Front Immunol. 2022;13:773288 pubmed publisher
Vogel A, Martin K, Soukup K, Halfmann A, Kerndl M, Brunner J, et al. JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction. Cell Rep. 2022;38:110420 pubmed publisher
Kemble S, Dalby A, Lowe G, Nicolson P, Watson S, Senis Y, et al. Analysis of preplatelets and their barbell platelet derivatives by imaging flow cytometry. Blood Adv. 2022;6:2932-2946 pubmed publisher
Li L, Ding Q, Zhou J, Wu Y, Zhang M, Guo X, et al. Distinct binding kinetics of E-, P- and L-selectins to CD44. FEBS J. 2022;289:2877-2894 pubmed publisher
Beatson R, Parente Pereira A, Halim L, Cozzetto D, Hull C, Whilding L, et al. TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer. Cell Rep Med. 2021;2:100473 pubmed publisher
Lehrke M, Shapiro M, Rajcula M, Kennedy M, McCue S, Medina K, et al. The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice. elife. 2021;10: pubmed publisher
Liang Y, Chen K, Tsai J, Cheng Y, Lee C, Kao C, et al. Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells. J Biomed Sci. 2021;28:75 pubmed publisher
Ray J, Ralff M, Jhaveri A, Zhou L, Dicker D, Ross E, et al. Antitumorigenic effect of combination treatment with ONC201 and TRAIL in endometrial cancer in vitro and in vivo. Cancer Biol Ther. 2021;22:554-563 pubmed publisher
Shibuya M, Tamiya S, Kawai A, Hirai T, Cragg M, Yoshioka Y. Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza. iScience. 2021;24:103131 pubmed publisher
Fei D, Xia Y, Zhai Q, Wang Y, Zhou F, Zhao W, et al. Exosomes Regulate Interclonal Communication on Osteogenic Differentiation Among Heterogeneous Osteogenic Single-Cell Clones Through PINK1/Parkin-Mediated Mitophagy. Front Cell Dev Biol. 2021;9:687258 pubmed publisher
Ishii Y, Kolluri K, Pennycuick A, Zhang X, Nigro E, Alrifai D, et al. BAP1 and YY1 regulate expression of death receptors in malignant pleural mesothelioma. J Biol Chem. 2021;297:101223 pubmed publisher
Yamin R, Jones A, Hoffmann H, Schäfer A, Kao K, Francis R, et al. Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy. Nature. 2021;599:465-470 pubmed publisher
Merah Mourah F, Cohen S, Haziot A. A Two-Stage Flow Cytometry Strategy to Distinguish Single Cells from Doublets in Heterogeneous Cell Mixtures and Improve Cell Cluster Identification: Application to Human Monocyte Subpopulations. Curr Protoc. 2021;1:e229 pubmed publisher
Song S, Manook M, Kwun J, Jackson A, Knechtle S, Kelsoe G. Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells. Front Immunol. 2021;12:705140 pubmed publisher
O Connor R, Chauhan V, Mathieson L, Titmarsh H, Koppensteiner L, Young I, et al. T cells drive negative feedback mechanisms in cancer associated fibroblasts, promoting expression of co-inhibitory ligands, CD73 and IL-27 in non-small cell lung cancer. Oncoimmunology. 2021;10:1940675 pubmed publisher
Yamada S, Yassin M, Schwarz T, Hansmann J, Mustafa K. Induction of osteogenic differentiation of bone marrow stromal cells on 3D polyester-based scaffolds solely by subphysiological fluidic stimulation in a laminar flow bioreactor. J Tissue Eng. 2021;12:20417314211019375 pubmed publisher
Karagianni A, Eaton S, Kurian D, Cill xe1 n Garcia E, Twynam Perkins J, Raper A, et al. Application across species of a one health approach to liquid sample handling for respiratory based -omics analysis. Sci Rep. 2021;11:14292 pubmed publisher
Sahillioğlu A, Toebes M, Apriamashvili G, Gomez R, Schumacher T. CRASH-IT Switch Enables Reversible and Dose-Dependent Control of TCR and CAR T-cell Function. Cancer Immunol Res. 2021;9:999-1007 pubmed publisher
Luo Y, Xu C, Wang B, Niu Q, Su X, Bai Y, et al. Single-cell transcriptomic analysis reveals disparate effector differentiation pathways in human Treg compartment. Nat Commun. 2021;12:3913 pubmed publisher
Garcia Larragoiti N, Kim Y, Lopez Camacho C, Cano Mendez A, Lopez Castaneda S, Hernández Hernández D, et al. Platelet activation and aggregation response to dengue virus nonstructural protein 1 and domains. J Thromb Haemost. 2021;: pubmed publisher
Liu S, Polsdofer E, Zhou L, Ruan S, Lyu H, Hou D, et al. Upregulation of endogenous TRAIL-elicited apoptosis is essential for metformin-mediated antitumor activity against TNBC and NSCLC. Mol Ther Oncolytics. 2021;21:303-314 pubmed publisher
Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito K, et al. Extracellular mRNA transported to the nucleus exerts translation-independent function. Nat Commun. 2021;12:3655 pubmed publisher
Shao L, He Q, Wang J, He F, Lin S, Wu L, et al. MicroRNA-326 attenuates immune escape and prevents metastasis in lung adenocarcinoma by targeting PD-L1 and B7-H3. Cell Death Discov. 2021;7:145 pubmed publisher
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski K, Alicea Torres K, et al. Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs. Nat Cancer. 2020;1:603-619 pubmed publisher
Loo Yau H, De Carvalho D. Measuring the effect of drug treatments on primary human CD8+ T cell activation and cytolytic potential. STAR Protoc. 2021;2:100549 pubmed publisher
Park J, Park H, Lee Y, Weon S, Kim Y, Yang J, et al. Blocking TNFα attenuates progressive cartilage matrix degradation in inflammatory arthritis. Exp Ther Med. 2021;22:808 pubmed publisher
Mohammadi M, Rodriguez S, Luong J, Li S, Cao R, Alshetaiwi H, et al. Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation. Commun Biol. 2021;4:685 pubmed publisher
Soto Pantoja D, Gaber M, Arnone A, Bronson S, Cruz Diaz N, Wilson A, et al. Diet Alters Entero-Mammary Signaling to Regulate the Breast Microbiome and Tumorigenesis. Cancer Res. 2021;81:3890-3904 pubmed publisher
Perelman S, James D, Boguslawski K, Nelson C, Ilmain J, Zwack E, et al. Genetic variation of staphylococcal LukAB toxin determines receptor tropism. Nat Microbiol. 2021;6:731-745 pubmed publisher
Iwabuchi R, Ide K, Terahara K, Wagatsuma R, Iwaki R, Matsunaga H, et al. Development of an Inflammatory CD14+ Dendritic Cell Subset in Humanized Mice. Front Immunol. 2021;12:643040 pubmed publisher
Deng Z, Jing Z, Guo Y, Ma J, Yan H, Shi Z, et al. Expression of immunoglobulin G in human proximal tubular epithelial cells. Mol Med Rep. 2021;23: pubmed publisher
Grayson K, Hope J, Wang W, Reinhart King C, King M. Taxanes Sensitize Prostate Cancer Cells to TRAIL-Induced Apoptotic Synergy via Endoplasmic Reticulum Stress. Mol Cancer Ther. 2021;20:833-845 pubmed publisher
Kawamoto E, Nago N, Okamoto T, Gaowa A, Masui Ito A, Akama Y, et al. The Lectin-Like Domain of Thrombomodulin Inhibits β1 Integrin-Dependent Binding of Human Breast Cancer-Derived Cell Lines to Fibronectin. Biomedicines. 2021;9: pubmed publisher
Dam T, Junghans V, Humphrey J, Chouliara M, J xf6 nsson P. Calcium Signaling in T Cells Is Induced by Binding to Nickel-Chelating Lipids in Supported Lipid Bilayers. Front Physiol. 2020;11:613367 pubmed publisher
Vonderhaar E, Barnekow N, McAllister D, McOlash L, Eid M, Riese M, et al. STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer. Cell Mol Gastroenterol Hepatol. 2021;12:41-58 pubmed publisher
Stephens M, Liao S, von der Weid P. Ultra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function. Sci Rep. 2021;11:1335 pubmed publisher
Xin Y, Xu P, Wang X, Chen Y, Zhang Z, Zhang Y. Human foreskin-derived dermal stem/progenitor cell-conditioned medium combined with hyaluronic acid promotes extracellular matrix regeneration in diabetic wounds. Stem Cell Res Ther. 2021;12:49 pubmed publisher
Akhtar M, Mishra M, Yadav V, Yadav M, Gujar R, Lal S, et al. Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells. PLoS Pathog. 2020;16:e1009136 pubmed publisher
Srivastava S, Furlan S, Jaeger Ruckstuhl C, Sarvothama M, Berger C, Smythe K, et al. Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade. Cancer Cell. 2021;39:193-208.e10 pubmed publisher
Samuel R, Majd H, Richter M, Ghazizadeh Z, Zekavat S, Navickas A, et al. Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. Cell Stem Cell. 2020;27:876-889.e12 pubmed publisher
Tuttle K, Waugh K, Araya P, Minter R, Orlicky D, Ludwig M, et al. JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome. Cell Rep. 2020;33:108407 pubmed publisher
Peng H, Xue R, Ju Z, Qiu J, Wang J, Yan W, et al. Cancer-associated fibroblasts enhance the chemoresistance of CD73+ hepatocellular carcinoma cancer cells via HGF-Met-ERK1/2 pathway. Ann Transl Med. 2020;8:856 pubmed publisher
Tocheva A, Lerrer S, Mor A. In Vitro Assays to Study PD-1 Biology in Human T Cells. Curr Protoc Immunol. 2020;130:e103 pubmed publisher
Foltz L, Palacios Moreno J, Mayfield M, Kinch S, Dillon J, Syrenne J, et al. PAG1 directs SRC-family kinase intracellular localization to mediate receptor tyrosine kinase-induced differentiation. Mol Biol Cell. 2020;31:2269-2282 pubmed publisher
Junghans V, Chouliara M, Santos A, Hatherley D, Petersen J, Dam T, et al. Effects of a local auxiliary protein on the two-dimensional affinity of a TCR-peptide MHC interaction. J Cell Sci. 2020;133: pubmed publisher
Meng K, Majedi F, Thauland T, Butte M. Mechanosensing through YAP controls T cell activation and metabolism. J Exp Med. 2020;217: pubmed publisher
Majedi F, Hasani Sadrabadi M, Thauland T, Li S, Bouchard L, Butte M. T-cell activation is modulated by the 3D mechanical microenvironment. Biomaterials. 2020;252:120058 pubmed publisher
Tian R, Pan Y, Etheridge T, Deshmukh H, Gulick D, Gibson G, et al. Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals. Genes (Basel). 2020;11: pubmed publisher
Lee J, Jo S, Lee Y, Park H, Song J, Sung I, et al. Anterior cruciate ligament remnant cells have different potentials for cell differentiation based on their location. Sci Rep. 2020;10:3097 pubmed publisher
Mulas F, Wang X, Song S, Nishanth G, Yi W, Brunn A, et al. The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13. Cell Mol Immunol. 2020;: pubmed publisher
Wu Y, Kimura Y, Okamoto T, Matsuhisa K, Asada R, Saito A, et al. Inflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation. Sci Rep. 2019;9:20301 pubmed publisher
Sikder S, Rush C, Govan B, Alim M, Ketheesan N. Anti-streptococcal antibody and T-cell interactions with vascular endothelial cells initiate the development of rheumatic carditis. J Leukoc Biol. 2020;107:263-271 pubmed publisher
Grandclaudon M, Perrot Dockès M, Trichot C, Karpf L, Abouzid O, Chauvin C, et al. A Quantitative Multivariate Model of Human Dendritic Cell-T Helper Cell Communication. Cell. 2019;179:432-447.e21 pubmed publisher
Shiba T, Tanaka T, Ida H, Watanabe M, Nakaseko H, Osawa M, et al. Functional evaluation of the pathological significance of MEFV variants using induced pluripotent stem cell-derived macrophages. J Allergy Clin Immunol. 2019;144:1438-1441.e12 pubmed publisher
Dent J, Hetrick B, Tahvilian S, Sathe A, Greyslak K, LaBarge S, et al. Skeletal muscle mitochondrial function and exercise capacity are not impaired in mice with knockout of STAT3. J Appl Physiol (1985). 2019;127:1117-1127 pubmed publisher
Foight G, Wang Z, Wei C, Jr Greisen P, Warner K, Cunningham Bryant D, et al. Multi-input chemical control of protein dimerization for programming graded cellular responses. Nat Biotechnol. 2019;37:1209-1216 pubmed publisher
Bassaganyas L, Popa S, Horlbeck M, Puri C, Stewart S, Campelo F, et al. New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells. J Cell Biol. 2019;218:3861-3879 pubmed publisher
Mendoza Cabrera M, Navarro Hernández R, Santerre A, Ortiz Lazareno P, Pereira Suárez A, Estrada Chávez C. Effect of pregnancy hormone mixtures on cytokine production and surface marker expression in naïve and LPS-activated THP-1 differentiated monocytes/macrophages. Innate Immun. 2020;26:84-96 pubmed publisher
Shokri M, Bozorgmehr M, Ghanavatinejad A, Falak R, Aleahmad M, Kazemnejad S, et al. Human menstrual blood-derived stromal/stem cells modulate functional features of natural killer cells. Sci Rep. 2019;9:10007 pubmed publisher
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Liang Y, Yu B, Chen J, Wu H, Xu Y, Yang B, et al. Thymic stromal lymphopoietin epigenetically upregulates Fc receptor γ subunit-related receptors on antigen-presenting cells and induces TH2/TH17 polarization through dectin-2. J Allergy Clin Immunol. 2019;144:1025-1035.e7 pubmed publisher
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Gadkari M, Makiya M, Legrand F, Stokes K, Brown T, Howe K, et al. Transcript- and protein-level analyses of the response of human eosinophils to glucocorticoids. Sci Data. 2018;5:180275 pubmed publisher
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Zhang H, Zhang Z, Zhang L, Wang A, Zhu H, Li L, et al. Connexin 43 in splenic lymphocytes is involved in the regulation of CD4+CD25+ T lymphocyte proliferation and cytokine production in hypertensive inflammation. Int J Mol Med. 2018;41:13-24 pubmed publisher
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product information
Apps. Abbrev. :
FC, ICFC
Cat # :
400112
Clone :
MOPC-21
Item :
PE Mouse IgG1, κ Isotype Ctrl
Isotype :
Mouse IgG1, κ
Size :
100 μg
Price (USD) :
77 USD
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Application Notes :
Additional reported applications (for the relevant formats) include: Intracellular Flow Cytometry (ICFC), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB), Functional Assay (FA);
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA