product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified Mouse IgG1, κ Isotype Ctrl
catalog :
400101
quantity :
50 μg
price :
30 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MOPC-21
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, blocking or activating experiments
more info or order :
citations: 150
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 2
Lehnhardt A, Strecker M, Eiermann T, Marget M, Thaiss F, Nashan B, et al. High B-cell activating factor is not associated with worse 3-year graft outcome in blood group-incompatible kidney transplantation with rituximab induction. Clin Transplant. 2015;29:359-64 pubmed publisher
  • blocking or activating experiments; human
Chattergoon M, Latanich R, Quinn J, Winter M, Buckheit R, Blankson J, et al. HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon. PLoS Pathog. 2014;10:e1004082 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Kimura Y, van der Merwe M, Bering S, Penmatsa H, Conoley V, Sangild P, et al. Glucose transport by epithelia prepared from harvested enterocytes. Cytotechnology. 2015;67:39-49 pubmed publisher
Daimon T, Bhattacharya A, Wang K, Haratake N, Nakashoji A, Ozawa H, et al. MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells. Cell Death Discov. 2024;10:9 pubmed publisher
Hwang S, Awasthi D, Jeong J, Sandoval T, Chae C, Ramos Y, et al. Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function. Res Sq. 2023;: pubmed publisher
Wang X, Su S, Zhu Y, Cheng X, Cheng C, Chen L, et al. Metabolic Reprogramming via ACOD1 depletion enhances function of human induced pluripotent stem cell-derived CAR-macrophages in solid tumors. Nat Commun. 2023;14:5778 pubmed publisher
Worboys J, Vowell K, Hare R, Ambrose A, Bertuzzi M, Conner M, et al. TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation. Nat Commun. 2023;14:5016 pubmed publisher
Ma F, Plazyo O, Billi A, Tsoi L, Xing X, Wasikowski R, et al. Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis. Nat Commun. 2023;14:3455 pubmed publisher
Li X, Li J, Zheng Y, Lee S, Zhou J, Giobbie Hurder A, et al. Granulocyte-Macrophage Colony-Stimulating Factor Influence on Soluble and Membrane-Bound ICOS in Combination with Immune Checkpoint Blockade. Cancer Immunol Res. 2023;11:1100-1113 pubmed publisher
van Houtum E, Kers Rebel E, Looman M, Hooijberg E, B xfc ll C, Granado D, et al. Tumor cell-intrinsic and tumor microenvironmental conditions co-determine signaling by the glycoimmune checkpoint receptor Siglec-7. Cell Mol Life Sci. 2023;80:169 pubmed publisher
Banka A, Guevara M, Brannon E, Nguyen N, Song S, Cady G, et al. Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation. Nat Commun. 2023;14:2462 pubmed publisher
A R, Kunimura N, Tominaga S, Hirata E, Nishioka S, Uesugi M, et al. A recombinant adenovirus vector containing the synNotch receptor gene for the treatment of triple-negative breast cancer. Front Oncol. 2023;13:1147668 pubmed publisher
Gallucci L, Abele T, Fronza R, Stolp B, Laketa V, Sid Ahmed S, et al. Tissue-like environments shape functional interactions of HIV-1 with immature dendritic cells. EMBO Rep. 2023;24:e56818 pubmed publisher
Mascarau R, Woottum M, Fromont L, Gence R, Cantaloube Ferrieu V, Vahlas Z, et al. Productive HIV-1 infection of tissue macrophages by fusion with infected CD4+ T cells. J Cell Biol. 2023;222: pubmed publisher
Jiang B, Wang S, Song G, Jiang Q, Fan M, Fang C, et al. Hedgehog-induced ZFYVE21 promotes chronic vascular inflammation by activating NLRP3 inflammasomes in T cells. Sci Signal. 2023;16:eabo3406 pubmed publisher
Ghaffarinia A, Ayaydin F, P xf3 liska S, Manczinger M, Bolla B, Flink L, et al. Psoriatic Resolved Skin Epidermal Keratinocytes Retain Disease-Residual Transcriptomic and Epigenomic Profiles. Int J Mol Sci. 2023;24: pubmed publisher
Thompson Peach C, Fo xdf elteder J, Reinisch A, Thomas D. Thrombopoietin-independent Megakaryocyte Differentiation of Hematopoietic Progenitor Cells from Patients with Myeloproliferative Neoplasms. Bio Protoc. 2023;13:e4592 pubmed publisher
Troschke Meurer S, Zumpe M, Mei xdf ner L, Siebert N, Grabarczyk P, Forkel H, et al. Chemotherapeutics Used for High-Risk Neuroblastoma Therapy Improve the Efficacy of Anti-GD2 Antibody Dinutuximab Beta in Preclinical Spheroid Models. Cancers (Basel). 2023;15: pubmed publisher
Wang C, Choy F, Sanny A, Murakami T, Tan A, Lam K. An Inhibitory Role for Human CD96 Endodomain in T Cell Anti-Tumor Responses. Cells. 2023;12: pubmed publisher
Asashima H, Mohanty S, Comi M, Ruff W, Hoehn K, Wong P, et al. PD-1highCXCR5-CD4+ peripheral helper T cells promote CXCR3+ plasmablasts in human acute viral infection. Cell Rep. 2023;42:111895 pubmed publisher
Replogle J, Bonnar J, Pogson A, Liem C, Maier N, Ding Y, et al. Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. elife. 2022;11: pubmed publisher
Erlandsson M, Andersson K, Oparina N, Chandrasekaran V, Sághy T, Damdimopoulos A, et al. Survivin promotes a glycolytic switch in CD4+ T cells by suppressing the transcription of PFKFB3 in rheumatoid arthritis. iScience. 2022;25:105526 pubmed publisher
Matsuda T, Misato K, Tamiya S, Akeda Y, Nakase I, Kuroda E, et al. Efficient antigen delivery by dendritic cell-targeting peptide via nucleolin confers superior vaccine effects in mice. iScience. 2022;25:105324 pubmed publisher
Li Q, Sun X, Yu K, Lv J, Miao C, Yang J, et al. Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance. Cell Rep. 2022;40:111308 pubmed publisher
Bokharaie H, Kolch W, Krstic A. Analysis of Alternative mRNA Splicing in Vemurafenib-Resistant Melanoma Cells. Biomolecules. 2022;12: pubmed publisher
Peterson H, Chin L, Iwamoto Y, Oh J, Carlson J, Lee H, et al. Integrated Analytical System for Clinical Single-Cell Analysis. Adv Sci (Weinh). 2022;9:e2200415 pubmed publisher
Su M, Kumata S, Endo S, Okada Y, Takai T. LILRB4 promotes tumor metastasis by regulating MDSCs and inhibiting miR-1 family miRNAs. Oncoimmunology. 2022;11:2060907 pubmed publisher
Dai Z, Mu W, Zhao Y, Cheng J, Lin H, Ouyang K, et al. T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape. Signal Transduct Target Ther. 2022;7:85 pubmed publisher
Erlichman N, Baram T, Meshel T, Morein D, Da adoosh B, Ben Baruch A. Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes. Cancers (Basel). 2022;14: pubmed publisher
van der Sluis R, Cham L, Gris Oliver A, Gammelgaard K, Pedersen J, Idorn M, et al. TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection. EMBO J. 2022;41:e109622 pubmed publisher
Hagemans I, Wierstra P, Steuten K, Molkenboer Kuenen J, van Dalen D, ter Beest M, et al. Multiscale imaging of therapeutic anti-PD-L1 antibody localization using molecularly defined imaging agents. J Nanobiotechnology. 2022;20:64 pubmed publisher
Stepanenko A, Sosnovtseva A, Valikhov M, Chernysheva A, Cherepanov S, Yusubalieva G, et al. Superior infectivity of the fiber chimeric oncolytic adenoviruses Ad5/35 and Ad5/3 over Ad5-delta-24-RGD in primary glioma cultures. Mol Ther Oncolytics. 2022;24:230-248 pubmed publisher
Correia M, Stojanovic A, Wels W, Cerwenka A. Innate-like NKp30+CD8+ T cells armed with TCR/CAR target tumor heterogeneity. Oncoimmunology. 2021;10:1973783 pubmed publisher
Otano I, Azpilikueta A, Glez Vaz J, Alvarez M, Medina Echeverz J, Cortés Domínguez I, et al. CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation. Nat Commun. 2021;12:7296 pubmed publisher
Chowdhury D, Gardner J, Satpati A, Nookala S, Mukundan S, Porollo A, et al. Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity. Front Immunol. 2021;12:755961 pubmed publisher
Fujiwara Y, Tanno Y, Sugishita H, Kishi Y, Makino Y, Okada Y. Preparation of optimized concanavalin A-conjugated Dynabeads® magnetic beads for CUT&Tag. PLoS ONE. 2021;16:e0259846 pubmed publisher
Olety B, Peters P, Wu Y, Usami Y, Gottlinger H. HIV-1 propagation is highly dependent on basal levels of the restriction factor BST2. Sci Adv. 2021;7:eabj7398 pubmed publisher
Samoylenko A, K xf6 gler M, Zhyvolozhnyi A, Makieieva O, Bart G, Andoh S, et al. Time-gated Raman spectroscopy and proteomics analyses of hypoxic and normoxic renal carcinoma extracellular vesicles. Sci Rep. 2021;11:19594 pubmed publisher
Oleszycka E, Rodgers A, Xu L, Moynagh P. Dendritic Cell-Specific Role for Pellino2 as a Mediator of TLR9 Signaling Pathway. J Immunol. 2021;207:2325-2336 pubmed publisher
Luan H, Bailey T, Clubb R, Mohapatra B, Bhat A, Chakraborty S, et al. CHIP/STUB1 Ubiquitin Ligase Functions as a Negative Regulator of ErbB2 by Promoting Its Early Post-Biosynthesis Degradation. Cancers (Basel). 2021;13: pubmed publisher
Szodoray P, Andersen T, Heinzelbecker J, Imbery J, Huszthy P, Stanford S, et al. Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity. Cell Rep. 2021;36:109525 pubmed publisher
Stepanenko A, Sosnovtseva A, Valikhov M, Chekhonin V. A new insight into aggregation of oncolytic adenovirus Ad5-delta-24-RGD during CsCl gradient ultracentrifugation. Sci Rep. 2021;11:16088 pubmed publisher
Nagy Bal xf3 Z, Kiss R, Demeter J, B xf6 d xf6 r C, Bajtay Z, Erdei A. BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1. PLoS ONE. 2021;16:e0254853 pubmed publisher
Marozin S, Simon Nobbe B, Irausek S, Chung L, Lepperdinger G. Kinship of conditionally immortalized cells derived from fetal bone to human bone-derived mesenchymal stroma cells. Sci Rep. 2021;11:10933 pubmed publisher
Torrino S, Tiroille V, Dolfi B, Dufies M, Hinault C, Bonesso L, et al. UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling. elife. 2021;10: pubmed publisher
Perelman S, James D, Boguslawski K, Nelson C, Ilmain J, Zwack E, et al. Genetic variation of staphylococcal LukAB toxin determines receptor tropism. Nat Microbiol. 2021;6:731-745 pubmed publisher
Fraser S, Crooks M, Kaye P, Hart S. Distinct immune regulatory receptor profiles linked to altered monocyte subsets in sarcoidosis. ERJ Open Res. 2021;7: pubmed publisher
Myint P, Ito A, Appiah M, Obeng G, Darkwah S, Kawamoto E, et al. Irisin supports integrin-mediated cell adhesion of lymphocytes. Biochem Biophys Rep. 2021;26:100977 pubmed publisher
Kawamoto E, Nago N, Okamoto T, Gaowa A, Masui Ito A, Akama Y, et al. The Lectin-Like Domain of Thrombomodulin Inhibits β1 Integrin-Dependent Binding of Human Breast Cancer-Derived Cell Lines to Fibronectin. Biomedicines. 2021;9: pubmed publisher
Zhang Y, Zegers M, Nagelkerke A, Rowan A, Span P, Kouwer P. Tunable Hybrid Matrices Drive Epithelial Morphogenesis and YAP Translocation. Adv Sci (Weinh). 2021;8:2003380 pubmed publisher
Barragu xe9 H, Fontaine J, Abravanel F, Maur xe9 E, P xe9 ron J, Alric L, et al. Mobilization of γδ T Cells and IL-10 Production at the Acute Phase of Hepatitis E Virus Infection in Cytomegalovirus Carriers. J Immunol. 2021;206:1027-1038 pubmed publisher
Hwang H, Lee J, Kang S, Suh J, Choi E, Jang S, et al. The BTLA and PD-1 signaling pathways independently regulate the proliferation and cytotoxicity of human peripheral blood γδ T cells. Immun Inflamm Dis. 2021;9:274-287 pubmed publisher
Sundararaj K, Rodgers J, Angel P, Wolf B, Nowling T. The role of neuraminidase in TLR4-MAPK signalling and the release of cytokines by lupus serum-stimulated mesangial cells. Immunology. 2021;162:418-433 pubmed publisher
Hemkemeyer S, Vollmer V, Schwarz V, Lohmann B, Honnert U, Taha M, et al. Local Myo9b RhoGAP activity regulates cell motility. J Biol Chem. 2021;296:100136 pubmed publisher
Farrington L, Callaway P, Vance H, Baskevitch K, Lutz E, Warrier L, et al. Opsonized antigen activates Vδ2+ T cells via CD16/FCγRIIIa in individuals with chronic malaria exposure. PLoS Pathog. 2020;16:e1008997 pubmed publisher
Hagiwara K, Honma M, Harumoto T, Harada K, Sawada T, Yamamoto J, et al. Development of Prodrug Type Circular siRNA for In Vivo Knockdown by Systemic Administration. Nucleic Acid Ther. 2020;30:346-364 pubmed publisher
Li H, Wu H, Guo Q, Yu H, Xu Y, Yu J, et al. Myeloid-Derived Suppressor Cells Promote the Progression of Primary Membranous Nephropathy by Enhancing Th17 Response. Front Immunol. 2020;11:1777 pubmed publisher
Kim N, Kim M, Cho Y, Chen W, Lee K, Kim H. PVR and ICAM-1 on Blast Crisis CML Stem and Progenitor Cells with TKI Resistance Confer Susceptibility to NK Cells. Cancers (Basel). 2020;12: pubmed publisher
Mastoridis S, Londo xf1 o M, Kurt A, Kodela E, Crespo E, Mason J, et al. Impact of donor extracellular vesicle release on recipient cell "cross-dressing" following clinical liver and kidney transplantation. Am J Transplant. 2021;21:2387-2398 pubmed publisher
Tian R, Pan Y, Etheridge T, Deshmukh H, Gulick D, Gibson G, et al. Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals. Genes (Basel). 2020;11: pubmed publisher
Luk xe1 csi S, Gerecsei T, Bal xe1 zs K, Francz B, Szab xf3 B, Erdei A, et al. The differential role of CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in the adherence, migration and podosome formation of human macrophages and dendritic cells under inflammatory conditions. PLoS ONE. 2020;15:e0232432 pubmed publisher
Lugo Cintron K, Ayuso J, White B, Harari P, Ponik S, Beebe D, et al. Matrix density drives 3D organotypic lymphatic vessel activation in a microfluidic model of the breast tumor microenvironment. Lab Chip. 2020;20:1586-1600 pubmed publisher
Khanolkar A, Wilks J, Liu G, Caparelli E, De Moura M, Yap K, et al. Detailed Phenotypic and Functional Characterization of a Rare, Antibody-Dependent SLAM-Associated Protein Expression Pattern. Immunohorizons. 2020;4:153-164 pubmed publisher
Haruna M, Hirata M, Iwahori K, Kanazawa T, Yamamoto Y, Goto K, et al. Docetaxel Upregulates HMGB1 Levels in Non-small Cell Lung Cancer. Biol Pharm Bull. 2020;43:399-403 pubmed publisher
Okumura G, Iguchi Manaka A, Murata R, Yamashita Kanemaru Y, Shibuya A, Shibuya K. Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells. J Exp Med. 2020;217: pubmed publisher
Takeuchi T, Sears B, Lindeboom C, Lin Y, Fekaris N, Zienkiewicz K, et al. Chlamydomonas CHT7 Is Required for an Effective Quiescent State by Regulating Nutrient-Responsive Cell Cycle Gene Expression. Plant Cell. 2020;32:1240-1269 pubmed publisher
Panda S, Wigerblad G, Jiang L, Jiménez Andrade Y, Iyer V, Shen Y, et al. IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints. Proc Natl Acad Sci U S A. 2020;117:3103-3113 pubmed publisher
Rigau M, Ostrouska S, Fulford T, Johnson D, Woods K, Ruan Z, et al. Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells. Science. 2020;367: pubmed publisher
Obiedat A, Charpak Amikam Y, Tai Schmiedel J, Seidel E, Mahameed M, Avril T, et al. The integrated stress response promotes B7H6 expression. J Mol Med (Berl). 2020;98:135-148 pubmed publisher
Lamichhane R, Galvin H, Hannaway R, de la Harpe S, Munro F, Tyndall J, et al. Type I interferons are important co-stimulatory signals during T cell receptor mediated human MAIT cell activation. Eur J Immunol. 2020;50:178-191 pubmed publisher
Iga N, Otsuka A, Hirata M, Kataoka T, Irie H, Nakashima C, et al. Variable indoleamine 2,3-dioxygenase expression in acral/mucosal melanoma and its possible link to immunotherapy. Cancer Sci. 2019;110:3434-3441 pubmed publisher
Kegler A, Koristka S, Bergmann R, Berndt N, Arndt C, Feldmann A, et al. T cells engrafted with a UniCAR 28/z outperform UniCAR BB/z-transduced T cells in the face of regulatory T cell-mediated immunosuppression. Oncoimmunology. 2019;8:e1621676 pubmed publisher
Gravastrand C, Steinkjer B, Halvorsen B, Landsem A, Skjelland M, Jacobsen E, et al. Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. J Immunol. 2019;203:853-863 pubmed publisher
Hyun J, McMahon R, Lang A, Edwards J, Badilla A, Greene M, et al. HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells. PLoS Pathog. 2019;15:e1007883 pubmed publisher
Gu C, Wang L, Zurawski S, Oh S. Signaling Cascade through DC-ASGPR Induces Transcriptionally Active CREB for IL-10 Induction and Immune Regulation. J Immunol. 2019;: pubmed publisher
Whilding L, Halim L, Draper B, Parente Pereira A, Zabinski T, Davies D, et al. CAR T-Cells Targeting the Integrin αvβ6 and Co-Expressing the Chemokine Receptor CXCR2 Demonstrate Enhanced Homing and Efficacy against Several Solid Malignancies. Cancers (Basel). 2019;11: pubmed publisher
Xu Y, Huang D, Lü S, Zhang Y, Long M. Mechanical features of endothelium regulate cell adhesive molecule-induced calcium response in neutrophils. APL Bioeng. 2019;3:016104 pubmed publisher
Zaborowski M, Lee K, Na Y, Sammarco A, Zhang X, Iwanicki M, et al. Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles. Cell Rep. 2019;27:255-268.e6 pubmed publisher
Gong B, Kiyotani K, Sakata S, Nagano S, Kumehara S, Baba S, et al. Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer. J Exp Med. 2019;: pubmed publisher
Jiang L, Guo F, Liu X, Li X, Qin Q, Shu P, et al. Continuous targeted kinase inhibitors treatment induces upregulation of PD-L1 in resistant NSCLC. Sci Rep. 2019;9:3705 pubmed publisher
Logtenberg M, Jansen J, Raaben M, Toebes M, Franke K, Brandsma A, et al. Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy. Nat Med. 2019;25:612-619 pubmed publisher
Oh J, Kim M, Choi S, Ban Y, Lee H, Shin E, et al. Sustained Type I Interferon Reinforces NK Cell-Mediated Cancer Immunosurveillance During Chronic Virus Infection. Cancer Immunol Res. 2019;: pubmed publisher
Iwahori K, Shintani Y, Funaki S, Yamamoto Y, Matsumoto M, Yoshida T, et al. Peripheral T cell cytotoxicity predicts T cell function in the tumor microenvironment. Sci Rep. 2019;9:2636 pubmed publisher
Beug S, Cheung H, Sanda T, St Jean M, Beauregard C, Mamady H, et al. The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Sci Signal. 2019;12: pubmed publisher
Weckbach L, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, et al. Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. J Exp Med. 2019;216:350-368 pubmed publisher
Kinehara Y, Nagatomo I, Koyama S, Ito D, Nojima S, Kurebayashi R, et al. Semaphorin 7A promotes EGFR-TKI resistance in EGFR mutant lung adenocarcinoma cells. JCI Insight. 2018;3: pubmed publisher
Alvaro Benito M, Morrison E, Ebner F, Abualrous E, Urbicht M, Wieczorek M, et al. Distinct editing functions of natural HLA-DM allotypes impact antigen presentation and CD4+ T cell activation. Cell Mol Immunol. 2018;: pubmed publisher
Buchrieser J, Oliva Martin M, Moore M, Long J, Cowley S, Perez Simon J, et al. RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation. Cell Death Dis. 2018;9:973 pubmed publisher
Jelcić I, Al Nimer F, Wang J, Lentsch V, Planas R, Jelcic I, et al. Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis. Cell. 2018;175:85-100.e23 pubmed publisher
Kronstad L, Seiler C, Vergara R, Holmes S, Blish C. Differential Induction of IFN-? and Modulation of CD112 and CD54 Expression Govern the Magnitude of NK Cell IFN-? Response to Influenza A Viruses. J Immunol. 2018;201:2117-2131 pubmed publisher
Walwyn Brown K, Guldevall K, Saeed M, Pende D, Önfelt B, MacDonald A, et al. Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1. J Immunol. 2018;201:2028-2041 pubmed publisher
Gupta R, Yan X, Barrientos J, Kolitz J, Allen S, Rai K, et al. Mechanistic Insights into CpG DNA and IL-15 Synergy in Promoting B Cell Chronic Lymphocytic Leukemia Clonal Expansion. J Immunol. 2018;201:1570-1585 pubmed publisher
Rincón E, Rocha Gregg B, Collins S. A map of gene expression in neutrophil-like cell lines. BMC Genomics. 2018;19:573 pubmed publisher
Mastoridis S, Bertolino G, Whitehouse G, Dazzi F, Sanchez Fueyo A, Martinez Llordella M. Multiparametric Analysis of Circulating Exosomes and Other Small Extracellular Vesicles by Advanced Imaging Flow Cytometry. Front Immunol. 2018;9:1583 pubmed publisher
Tank E, Figueroa Romero C, Hinder L, Bedi K, Archbold H, Li X, et al. Abnormal RNA stability in amyotrophic lateral sclerosis. Nat Commun. 2018;9:2845 pubmed publisher
Urata S, Kenyon E, Nayak D, Cubitt B, Kurosaki Y, Yasuda J, et al. BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection. PLoS Pathog. 2018;14:e1007172 pubmed publisher
Bruening J, Lasswitz L, Banse P, Kahl S, Marinach C, Vondran F, et al. Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB. PLoS Pathog. 2018;14:e1007111 pubmed publisher
Heusinger E, Deppe K, Sette P, Krapp C, Kmiec D, Kluge S, et al. Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2. J Virol. 2018;92: pubmed publisher
Srpan K, Ambrose A, Karampatzakis A, Saeed M, Cartwright A, Guldevall K, et al. Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells. J Cell Biol. 2018;217:3267-3283 pubmed publisher
Watanabe K, Watanabe K, Watanabe Y, Fujioka D, Nakamura T, Nakamura K, et al. Human soluble phospholipase A2 receptor is an inhibitor of the integrin-mediated cell migratory response to collagen-I. Am J Physiol Cell Physiol. 2018;315:C398-C408 pubmed publisher
Yoshimura K, Matsuu A, Sasaki K, Momoi Y. Detection of Sirtuin-1 protein expression in peripheral blood leukocytes in dogs. J Vet Med Sci. 2018;80:1068-1076 pubmed publisher
Xiao W, Klement J, Lu C, Ibrahim M, Liu K. IFNAR1 Controls Autocrine Type I IFN Regulation of PD-L1 Expression in Myeloid-Derived Suppressor Cells. J Immunol. 2018;201:264-277 pubmed publisher
Ondigo B, Ndombi E, Nicholson S, Oguso J, Carter J, Kittur N, et al. Functional Studies of T Regulatory Lymphocytes in Human Schistosomiasis in Western Kenya. Am J Trop Med Hyg. 2018;98:1770-1781 pubmed publisher
He X, Kläsener K, Iype J, Becker M, Maity P, Cavallari M, et al. Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells. EMBO J. 2018;37: pubmed publisher
Takeda Y, Azuma M, Funami K, Shime H, Matsumoto M, Seya T. Type I Interferon-Independent Dendritic Cell Priming and Antitumor T Cell Activation Induced by a Mycoplasma fermentans Lipopeptide. Front Immunol. 2018;9:496 pubmed publisher
Derakhshandeh R, Sanadhya S, Lee Han K, Chen H, Goloubeva O, Webb T, et al. Semaphorin 4D in human head and neck cancer tissue and peripheral blood: A dense fibrotic peri-tumoral stromal phenotype. Oncotarget. 2018;9:11126-11144 pubmed publisher
Yu K, Davidson C, Wójtowicz A, Lisboa L, Wang T, Airo A, et al. LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions. J Clin Invest. 2018;128:1523-1537 pubmed publisher
Baranska A, Shawket A, Jouve M, Baratin M, Malosse C, Voluzan O, et al. Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal. J Exp Med. 2018;215:1115-1133 pubmed publisher
Yurchenko M, Skjesol A, Ryan L, Richard G, Kandasamy R, Wang N, et al. SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages. J Cell Biol. 2018;217:1411-1429 pubmed publisher
Nieto C, Bragado R, Municio C, Sierra Filardi E, Alonso B, Escribese M, et al. The Activin A-Peroxisome Proliferator-Activated Receptor Gamma Axis Contributes to the Transcriptome of GM-CSF-Conditioned Human Macrophages. Front Immunol. 2018;9:31 pubmed publisher
Parra Sánchez H, Puebla Clark L, Resendiz M, Valenzuela O, Hernandez J. Characterization and expression of DEC205 in the cDC1 and cDC2 subsets of porcine dendritic cells from spleen, tonsil, and submaxillary and mesenteric lymph nodes. Mol Immunol. 2018;96:1-7 pubmed publisher
Kim M, Kim C, Kim S, Shin S, Choe E, Park S, et al. YAP-Induced PD-L1 Expression Drives Immune Evasion in BRAFi-Resistant Melanoma. Cancer Immunol Res. 2018;: pubmed publisher
Pawlak E, Dirk B, Jacob R, Johnson A, Dikeakos J. The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells. Retrovirology. 2018;15:6 pubmed publisher
Cook J, Ueno N, Lodoen M. Toxoplasma gondii disrupts β1 integrin signaling and focal adhesion formation during monocyte hypermotility. J Biol Chem. 2018;293:3374-3385 pubmed publisher
Li N, Yang H, Wang M, Lü S, Zhang Y, Long M. Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling. Mol Biol Cell. 2018;29:408-418 pubmed publisher
Hutten T, Norde W, Woestenenk R, Wang R, Maas F, Kester M, et al. Increased Coexpression of PD-1, TIGIT, and KLRG-1 on Tumor-Reactive CD8+ T Cells During Relapse after Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2018;24:666-677 pubmed publisher
Jones N, Cronin J, Dolton G, Panetti S, Schauenburg A, Galloway S, et al. Metabolic Adaptation of Human CD4+ and CD8+ T-Cells to T-Cell Receptor-Mediated Stimulation. Front Immunol. 2017;8:1516 pubmed publisher
Slamecka J, McClellan S, Wilk A, Laurini J, Manci E, Hoerstrup S, et al. Induced pluripotent stem cells derived from human amnion in chemically defined conditions. Cell Cycle. 2018;17:330-347 pubmed publisher
Moreno Cubero E, Subira D, Sanz de Villalobos E, Parra Cid T, Madejon A, Miquel J, et al. According to Hepatitis C Virus (HCV) Infection Stage, Interleukin-7 Plus 4-1BB Triggering Alone or Combined with PD-1 Blockade Increases TRAF1low HCV-Specific CD8+ Cell Reactivity. J Virol. 2018;92: pubmed publisher
Al Akhrass H, Naves T, Vincent F, Magnaudeix A, Durand K, Bertin F, et al. Sortilin limits EGFR signaling by promoting its internalization in lung cancer. Nat Commun. 2017;8:1182 pubmed publisher
Veenhuis R, Freeman Z, Korleski J, Cohen L, Massaccesi G, Tomasi A, et al. HIV-antibody complexes enhance production of type I interferon by plasmacytoid dendritic cells. J Clin Invest. 2017;127:4352-4364 pubmed publisher
Su D, Vanhee S, Soria R, Gyllenbäck E, Starnes L, Højfeldt M, et al. PTIP chromatin regulator controls development and activation of B cell subsets to license humoral immunity in mice. Proc Natl Acad Sci U S A. 2017;114:E9328-E9337 pubmed publisher
Jain R, Sheridan J, Policheni A, Heinlein M, Gandolfo L, Dewson G, et al. A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice. Blood. 2017;130:2504-2515 pubmed publisher
Mathews J, Krishnamoorthy N, Kasahara D, Hutchinson J, Cho Y, Brand J, et al. Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide. Am J Respir Cell Mol Biol. 2018;58:341-351 pubmed publisher
Giannella A, Radu C, Franco L, Campello E, Simioni P, Avogaro A, et al. Circulating levels and characterization of microparticles in patients with different degrees of glucose tolerance. Cardiovasc Diabetol. 2017;16:118 pubmed publisher
Sharma N, Trinidad C, Trembath A, Markiewicz M. NKG2D Signaling between Human NK Cells Enhances TACE-Mediated TNF-α Release. J Immunol. 2017;199:2865-2872 pubmed publisher
Jensen H, Potempa M, Gotthardt D, Lanier L. Cutting Edge: IL-2-Induced Expression of the Amino Acid Transporters SLC1A5 and CD98 Is a Prerequisite for NKG2D-Mediated Activation of Human NK Cells. J Immunol. 2017;199:1967-1972 pubmed publisher
Suwanpradid J, Shih M, Pontius L, Yang B, Birukova A, Guttman Yassky E, et al. Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. J Immunol. 2017;199:1827-1834 pubmed publisher
Takeuchi H, Yu H, Hao H, Takeuchi M, Ito A, Li H, et al. O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking. J Biol Chem. 2017;292:15964-15973 pubmed publisher
Nakajima N, Niimi A, Isono M, Oike T, Sato H, Nakano T, et al. Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells. Oncol Rep. 2017;38:693-702 pubmed publisher
Moreira Teixeira L, Redford P, Stavropoulos E, Ghilardi N, Maynard C, Weaver C, et al. T Cell-Derived IL-10 Impairs Host Resistance to Mycobacterium tuberculosis Infection. J Immunol. 2017;199:613-623 pubmed publisher
Lagumersindez Denis N, Wrzos C, Mack M, Winkler A, van der Meer F, Reinert M, et al. Differential contribution of immune effector mechanisms to cortical demyelination in multiple sclerosis. Acta Neuropathol. 2017;134:15-34 pubmed publisher
Sindhava V, Oropallo M, Moody K, Naradikian M, Higdon L, Zhou L, et al. A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens. J Clin Invest. 2017;127:1651-1663 pubmed publisher
Lopes F, Bálint Å, Valvo S, Felce J, Hessel E, Dustin M, et al. Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages. J Cell Biol. 2017;216:1123-1141 pubmed publisher
Hess N, Felicelli C, Grage J, Tapping R. TLR10 suppresses the activation and differentiation of monocytes with effects on DC-mediated adaptive immune responses. J Leukoc Biol. 2017;101:1245-1252 pubmed publisher
Jensen H, Chen S, Folkersen L, Nolan G, Lanier L. EBI3 regulates the NK cell response to mouse cytomegalovirus infection. Proc Natl Acad Sci U S A. 2017;114:1625-1630 pubmed publisher
Schober T, Magg T, Laschinger M, Rohlfs M, Linhares N, Puchalka J, et al. A human immunodeficiency syndrome caused by mutations in CARMIL2. Nat Commun. 2017;8:14209 pubmed publisher
Abolhassani H, Edwards E, Ikinciogullari A, Jing H, Borte S, Buggert M, et al. Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency. J Exp Med. 2017;214:91-106 pubmed publisher
Lévy R, Okada S, Béziat V, Moriya K, Liu C, Chai L, et al. Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency. Proc Natl Acad Sci U S A. 2016;113:E8277-E8285 pubmed publisher
Albanese M, Tagawa T, Bouvet M, Maliqi L, Lutter D, Hoser J, et al. Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells. Proc Natl Acad Sci U S A. 2016;113:E6467-E6475 pubmed
Tagawa T, Albanese M, Bouvet M, Moosmann A, Mautner J, Heissmeyer V, et al. Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing. J Exp Med. 2016;213:2065-80 pubmed publisher
Now H, Yoo J. AG490 and PF431396 Sensitive Tyrosine Kinase Control the Population Heterogeneity of Basal STAT1 Activity in Ube1l Deficient Cells. PLoS ONE. 2016;11:e0159453 pubmed publisher
Karlas A, Berrè S, Couderc T, Varjak M, Braun P, Meyer M, et al. A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs. Nat Commun. 2016;7:11320 pubmed publisher
Leitch C, Natafji E, Yu C, Abdul Ghaffar S, Madarasingha N, Venables Z, et al. Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells. J Allergy Clin Immunol. 2016;138:482-490.e7 pubmed publisher
Ohradanova Repic A, Machacek C, Fischer M, Stockinger H. Differentiation of human monocytes and derived subsets of macrophages and dendritic cells by the HLDA10 monoclonal antibody panel. Clin Transl Immunology. 2016;5:e55 pubmed publisher
Rancan C, Schirrmann L, Hüls C, Zeidler R, Moosmann A. Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells. PLoS Pathog. 2015;11:e1004906 pubmed publisher
Bufe B, Schumann T, Kappl R, Bogeski I, Kummerow C, Podgórska M, et al. Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens. J Biol Chem. 2015;290:7369-87 pubmed publisher
Lian I, Løset M, Mundal S, Fenstad M, Johnson M, Eide I, et al. Increased endoplasmic reticulum stress in decidual tissue from pregnancies complicated by fetal growth restriction with and without pre-eclampsia. Placenta. 2011;32:823-9 pubmed publisher
Smed Sorensen A, Moll M, Cheng T, Lore K, Norlin A, Perbeck L, et al. IgG regulates the CD1 expression profile and lipid antigen-presenting function in human dendritic cells via FcgammaRIIa. Blood. 2008;111:5037-46 pubmed publisher
Carlsten M, Björkström N, Norell H, Bryceson Y, van Hall T, Baumann B, et al. DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells. Cancer Res. 2007;67:1317-25 pubmed
product information
Apps. Abbrev. :
FC, ICFC, ICC, IHC, IP, WB, FA, ChIP
Cat # :
400101
Clone :
MOPC-21
Item :
Purified Mouse IgG1, κ Isotype Ctrl
Isotype :
Mouse IgG1, κ
Size :
50 μg
Price (USD) :
30 USD
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Application Notes :
Additional reported applications (for the relevant formats) include: Intracellular Flow Cytometry (ICFC), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB), Functional Assay (FA);
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA