product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human/mouse Granzyme B Recombinant
catalog :
396413
quantity :
25 tests
price :
198 USD
clonality :
recombinant
host :
rat
conjugate :
BV421
clone name :
QA18A28
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 8a
Wang F, Ye W, Wang S, He Y, Zhong H, Wang Y, et al. Discovery of a new inhibitor targeting PD-L1 for cancer immunotherapy. Neoplasia. 2021;23:281-293 pubmed publisher
Yang Q, Wang S, Liu Y, Song A, Wu Z, Wan S, et al. Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer. iScience. 2023;26:106916 pubmed publisher
Lin C, Talebian F, Li Y, Zhu J, Liu J, Zhao B, et al. CD200R signaling contributes to unfavorable tumor microenvironment through regulating production of chemokines by tumor-associated myeloid cells. iScience. 2023;26:106904 pubmed publisher
Wang F, Ye W, He Y, Zhong H, Zhu Y, Han J, et al. Identification of CBPA as a New Inhibitor of PD-1/PD-L1 Interaction. Int J Mol Sci. 2023;24: pubmed publisher
Peng W, Ye L, Xue Q, Wei X, Wang Z, Xiang X, et al. Silencing of circCRIM1 Drives IGF2BP1-Mediated NSCLC Immune Evasion. Cells. 2023;12: pubmed publisher
Jin S, Yoo Y, Shin H, Kim S, Lee S, Lee C, et al. A nanoadjuvant that dynamically coordinates innate immune stimuli activation enhances cancer immunotherapy and reduces immune cell exhaustion. Nat Nanotechnol. 2023;18:390-402 pubmed publisher
Lin Y, Duong H, Limary A, Kim E, Hsu P, Patel S, et al. Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes. Immunity. 2023;56:207-223.e8 pubmed publisher
Wu J, Wang X, Chen L, Wang J, Zhang J, Tang J, et al. Oxygen microcapsules improve immune checkpoint blockade by ameliorating hypoxia condition in pancreatic ductal adenocarcinoma. Bioact Mater. 2023;20:259-270 pubmed publisher
Xie Z, Wang Z, Fan F, Zhou J, Hu Z, Wang Q, et al. Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation. Cell Discov. 2022;8:133 pubmed publisher
Liang Y, Li X, Peng F, Ye X, Wang W, Cen T, et al. Self-assembly of X-shaped antibody to combine the activity of IgG and IgA for enhanced tumor killing. Theranostics. 2022;12:7729-7744 pubmed publisher
Toomer G, Burns W, Garcia L, Henry G, Biancofiori A, George A, et al. Characterization of Three Variants of SARS-CoV-2 In Vivo Shows Host-Dependent Pathogenicity in Hamsters, While Not in K18-hACE2 Mice. Viruses. 2022;14: pubmed publisher
Wilson T, Kim H, Chou C, Langfitt D, Mettelman R, Minervina A, et al. Common trajectories of highly effective CD19-specific CAR T cells identified by endogenous T cell receptor lineages. Cancer Discov. 2022;: pubmed publisher
Hirschberger S, Gellert L, Effinger D, Muenchhoff M, Herrmann M, Briegel J, et al. Ketone Bodies Improve Human CD8+ Cytotoxic T-Cell Immune Response During COVID-19 Infection. Front Med (Lausanne). 2022;9:923502 pubmed publisher
Duan H, Jing L, Jiang X, Ma Y, Wang D, Xiang J, et al. CD146 bound to LCK promotes T cell receptor signaling and antitumor immune responses in mice. J Clin Invest. 2021;131: pubmed publisher
Zhang X, Huang X, Xu J, Li E, Lao M, Tang T, et al. NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1. Nat Commun. 2021;12:4536 pubmed publisher
Hirschberger S, Strauß G, Effinger D, Marstaller X, Ferstl A, Müller M, et al. Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming. EMBO Mol Med. 2021;13:e14323 pubmed publisher
Shuwa H, Shaw T, Knight S, Wemyss K, McClure F, Pearmain L, et al. Alterations in T and B cell function persist in convalescent COVID-19 patients. Med (N Y). 2021;2:720-735.e4 pubmed publisher
Jiang X, Wang G, Zhao X, Yan F, Yao L, Kou Z, et al. Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection. Nat Commun. 2021;12:897 pubmed publisher
Viaud M, Abdel Wahab O, Gall J, Ivanov S, Guinamard R, Sore S, et al. ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms. Cell Rep. 2020;30:3397-3410.e5 pubmed publisher
product information
Antigen :
Granzyme B
Apps. Abbrev. :
ICFC
Cat # :
396413
Clone :
QA18A28
Item :
Brilliant Violet 421™ anti-human/mouse Granzyme B Recombinant
Isotype :
Rat IgG1, κ
Other Names :
Granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1, GZMB, CCP1, Asp-aseGranzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1, GZMB, CCP1, Asp-ase
Size :
25 tests
Price (USD) :
198 USD
Reactivity :
Human, Mouse
Clonality :
Recombinant
Host :
Rat
Conjugate/Tag/Label :
BV421
Application Notes :
Clone QA18A28 is compatible with Fixation buffer (Cat. No. 420801) and Intracellular Staining Permeabilization Wash Buffer (Cat. No. 421002) in both C57BL/6 splenocytes and human PBMC. QA18A28 is also compatible with True-Nuclear™ Transcription Factor Buffer Set (Cat. No. 424401).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA