product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human CD8a
catalog :
372902
quantity :
100 μg
price :
59 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C8/144B
reactivity :
common marmoset
application :
western blot, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 11
Reference
Nickl V, Eck J, Goedert N, H xfc bner J, Nerreter T, Hagemann C, et al. Characterization and Optimization of the Tumor Microenvironment in Patient-Derived Organotypic Slices and Organoid Models of Glioblastoma. Cancers (Basel). 2023;15: pubmed publisher
Mokhtari Z, Rezaei M, Sanei M, Dehghanian A, Faghih Z, Heidari Z, et al. Tim3 and PD-1 as a therapeutic and prognostic targets in colorectal cancer: Relationship with sidedness, clinicopathological parameters, and survival. Front Oncol. 2023;13:1069696 pubmed publisher
Cai Z, Chen J, Yu Z, Li H, Liu Z, Deng D, et al. BCAT2 Shapes a Noninflamed Tumor Microenvironment and Induces Resistance to Anti-PD-1/PD-L1 Immunotherapy by Negatively Regulating Proinflammatory Chemokines and Anticancer Immunity. Adv Sci (Weinh). 2023;10:e2207155 pubmed publisher
Zheng Y, Han L, Chen Z, Li Y, Zhou B, Hu R, et al. PD-L1+CD8+ T cells enrichment in lung cancer exerted regulatory function and tumor-promoting tolerance. iScience. 2022;25:103785 pubmed publisher
Zhang W, Zhong W, Wang B, Yang J, Yang J, Yu Z, et al. ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression. Dev Cell. 2022;57:329-343.e7 pubmed publisher
Rye I, Huse K, Josefsson S, Kildal W, Danielsen H, Schlichting E, et al. Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression. Mol Oncol. 2022;16:88-103 pubmed publisher
Chang M, Levescot A, Nelson Maney N, Blaustein R, Winden K, Morris A, et al. Arthritis flares mediated by tissue-resident memory T cells in the joint. Cell Rep. 2021;37:109902 pubmed publisher
Schwabenland M, Salié H, Tanevski J, Killmer S, Lago M, Schlaak A, et al. Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions. Immunity. 2021;54:1594-1610.e11 pubmed publisher
Wen J, Huang G, Liu S, Wan J, Wang X, Zhu Y, et al. Polymorphonuclear MDSCs are enriched in the stroma and expanded in metastases of prostate cancer. J Pathol Clin Res. 2020;6:171-177 pubmed publisher
Giadans C, Ríos D, Ameigeiras B, Pietrantonio A, Lucatelli N, Haddad L, et al. Chronic hepatitis B: The interplay between intrahepatic lymphocyte population and viral antigens in relation to liver damage. J Viral Hepat. 2019;26:727-737 pubmed publisher
Sade Feldman M, Yizhak K, Bjorgaard S, Ray J, de Boer C, Jenkins R, et al. Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma. Cell. 2018;175:998-1013.e20 pubmed publisher
product information
Antigen :
CD8a
Apps. Abbrev. :
IHC-P, Activ, FC, IHC-F, WB
Cat # :
372902
Clone :
C8/144B
Item :
Purified anti-human CD8a
Isotype :
Mouse IgG1, κ
Other Names :
T8, Leu2
Size :
100 μg
Price (USD) :
59 USD
Reactivity :
Human, Mouse, Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of the alpha chain of the human CD8 molecule.
Application Notes :
Additional reported applications (for the relevant formats) include activation^3, flow cytometry^4, immunohistochemical staining of frozen tissue sections^2, and Western blotting^5.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA