product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
TotalSeq™-C0089 anti-human TIGIT (VSTM3)
catalog :
372729
quantity :
10 μg
price :
369 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A15153G
reactivity :
human, mouse
application :
flow cytometry, other
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Jin Y, Lorvik K, Jin Y, Beck C, Sike A, Persiconi I, et al. Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer. Mol Ther Oncolytics. 2022;26:189-206 pubmed publisher
  • flow cytometry; human; 1:100; loading ...; fig 5c
Niebel D, Fr xf6 hlich A, Zarbl R, Fietz S, de Vos L, Vogt T, et al. DNA methylation regulates TIGIT expression within the melanoma microenvironment, is prognostic for overall survival, and predicts progression-free survival in patients treated with anti-PD-1 immunotherapy. Clin Epigenetics. 2022;14:50 pubmed publisher
  • other; mouse
Tseng H, Xiong W, Badeti S, Yang Y, Ma M, Liu T, et al. Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. Nat Commun. 2020;11:4810 pubmed publisher
  • flow cytometry; human; fig 4d
Marotte L, Simon S, Vignard V, Dupré E, Gantier M, Cruard J, et al. Increased antitumor efficacy of PD-1-deficient melanoma-specific human lymphocytes. J Immunother Cancer. 2020;8: pubmed publisher
Vyasamneni R, Kohler V, Karki B, Mahimkar G, Esaulova E, McGee J, et al. A universal MHCII technology platform to characterize antigen-specific CD4+ T cells. Cell Rep Methods. 2023;3:100388 pubmed publisher
Collora J, Liu R, Pinto Santini D, Ravindra N, Ganoza C, Lama J, et al. Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones. Immunity. 2022;55:1013-1031.e7 pubmed publisher
Bachireddy P, Azizi E, Burdziak C, Nguyen V, Ennis C, Maurer K, et al. Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy. Cell Rep. 2021;37:109992 pubmed publisher
Pizzolla A, Keam S, D Souza C, Semple T, Neeson P. Single-Cell Gene Expression, Clonality, and Feature Barcoding of Melanoma Tumor-Infiltrating Lymphocytes. Methods Mol Biol. 2021;2265:529-541 pubmed publisher
Morad G, Daisy C, Otu H, Libermann T, Dillon S, Moses M. Cdc42-Dependent Transfer of mir301 from Breast Cancer-Derived Extracellular Vesicles Regulates the Matrix Modulating Ability of Astrocytes at the Blood-Brain Barrier. Int J Mol Sci. 2020;21: pubmed publisher
Stamm H, Klingler F, Grossjohann E, Muschhammer J, Vettorazzi E, Heuser M, et al. Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option. Oncogene. 2018;37:5269-5280 pubmed publisher
product information
Antigen :
TIGIT
Apps. Abbrev. :
PG
Cat # :
372729
Clone :
A15153G
Item :
TotalSeq™-C0089 anti-human TIGIT (VSTM3)
Isotype :
Mouse IgG2a, κ
Other Names :
T-cell immunoreceptor with Ig and ITIM domains, VSIG9, VSTM3, WUCAM
Size :
10 μg
Price (USD) :
369 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
TOTALSEQ_C
Immunogen :
Recombinant Human TIGIT.
Application Notes :
This clone can suppress anti-CD3 induced T cell proliferation in vitro based on in-house testing.This clone has been tested in-house and determined to not be suitable for applications in immunohistochemistry of paraffin-embedded tissue sections (IHC-P).Additional reported applications (for the relevant formats) include: Blocking^1.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA