Alexa Fluor® 647 anti-human TIGIT (VSTM3) | BioLegend 372724 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 647 anti-human TIGIT (VSTM3)

catalog :

372724

quantity :

100 tests

price :

405 USD

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

A15153G

reactivity :

human, mouse

application :

flow cytometry, blocking or activating experiments, other

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse	Jin Y, Lorvik K, Jin Y, Beck C, Sike A, Persiconi I, et al. Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer. Mol Ther Oncolytics. 2022;26:189-206 pubmed publisher
flow cytometry; human; 1:100; loading ...; fig 5c	Niebel D, Fr xf6 hlich A, Zarbl R, Fietz S, de Vos L, Vogt T, et al. DNA methylation regulates TIGIT expression within the melanoma microenvironment, is prognostic for overall survival, and predicts progression-free survival in patients treated with anti-PD-1 immunotherapy. Clin Epigenetics. 2022;14:50 pubmed publisher
other; mouse	Tseng H, Xiong W, Badeti S, Yang Y, Ma M, Liu T, et al. Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. Nat Commun. 2020;11:4810 pubmed publisher
flow cytometry; human; fig 4d	Marotte L, Simon S, Vignard V, Dupré E, Gantier M, Cruard J, et al. Increased antitumor efficacy of PD-1-deficient melanoma-specific human lymphocytes. J Immunother Cancer. 2020;8: pubmed publisher
blocking or activating experiments; human; loading ...; fig 4d, 4e	Stamm H, Klingler F, Grossjohann E, Muschhammer J, Vettorazzi E, Heuser M, et al. Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option. Oncogene. 2018;37:5269-5280 pubmed publisher
	Lam A, Lin D, Gillies J, Uday P, Pesenacker A, Kobor M, et al. Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity. Cell Rep. 2021;36:109494 pubmed publisher
	Schultheiß C, Paschold L, Simnica D, Mohme M, Willscher E, von Wenserski L, et al. Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease. Immunity. 2020;53:442-455.e4 pubmed publisher
	Thokala R, Olivares S, Mi T, Maiti S, Deniger D, Huls H, et al. Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of VL and VH Domains Targeting CD123+ Tumors. PLoS ONE. 2016;11:e0159477 pubmed publisher

product information

Antigen :

TIGIT

Apps. Abbrev. :

Cat # :

372724

Clone :

A15153G

Item :

Alexa Fluor® 647 anti-human TIGIT (VSTM3)

Isotype :

Mouse IgG2a, κ

Other Names :

T-cell immunoreceptor with Ig and ITIM domains, VSIG9, VSTM3, WUCAM

Size :

100 tests

Price (USD) :

405 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

A647

Immunogen :

Recombinant Human TIGIT.

Application Notes :

This clone can suppress anti-CD3 induced T cell proliferation in vitro based on in-house testing.This clone has been tested in-house and determined to not be suitable for applications in immunohistochemistry of paraffin-embedded tissue sections (IHC-P).Additional reported applications (for the relevant formats) include: Blocking^1.;

more info or order :

BioLegend product webpage