product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD152 (CTLA-4)
catalog :
369612
quantity :
100 tests
price :
264 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
BNI3
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 9
Reference
Lu T, Zhang J, Lu S, Yang F, Gan L, Wu X, et al. Endosialin-positive tumor-derived pericytes promote tumor progression through impeding the infiltration of CD8+ T cells in clear cell renal cell carcinoma. Cancer Immunol Immunother. 2023;72:1739-1750 pubmed publisher
Gan X, Shan Q, Li H, Janssens R, Shen Y, He Y, et al. An anti-CTLA-4 heavy chain-only antibody with enhanced Treg depletion shows excellent preclinical efficacy and safety profile. Proc Natl Acad Sci U S A. 2022;119:e2200879119 pubmed publisher
Lee P, Macdonald K, Massi E, Chew P, Bee C, Perkins P, et al. Improved therapeutic index of an acidic pH-selective antibody. MAbs. 2022;14:2024642 pubmed publisher
Yuan H, Nishikori M, Ueda C, Fujimoto M, Yasumi T, Otsuka Y, et al. A sporadic case of CTLA4 haploinsufficiency manifesting as Epstein-Barr virus-positive diffuse large B-cell lymphoma. J Clin Exp Hematop. 2022;62:52-57 pubmed publisher
Gamradt S, Hasselmann H, Taenzer A, Brasanac J, Stiglbauer V, Sattler A, et al. Reduced mitochondrial respiration in T cells of patients with major depressive disorder. iScience. 2021;24:103312 pubmed publisher
Ping Y, Li F, Nan S, Zhang D, Shi X, Shan J, et al. Augmenting the Effectiveness of CAR-T Cells by Enhanced Self-Delivery of PD-1-Neutralizing scFv. Front Cell Dev Biol. 2020;8:803 pubmed publisher
Navarrete Bernal M, Cervantes Badillo M, Martínez Herrera J, Lara Torres C, Gerson Cwilich R, Zentella Dehesa A, et al. Biological Landscape of Triple Negative Breast Cancers Expressing CTLA-4. Front Oncol. 2020;10:1206 pubmed publisher
Wang X, Li W, Zhu D, Zhao H, Chen P, Chen X. Characterization of human peripheral blood γδ T cells in patients with sepsis. Exp Ther Med. 2020;19:3698-3706 pubmed publisher
Franchini D, Lanvin O, Tosolini M, Patras de Campaigno E, Cammas A, Péricart S, et al. Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells. Cell Rep. 2019;26:94-107.e7 pubmed publisher
product information
Antigen :
CD152
Apps. Abbrev. :
FC, ICFC
Cat # :
369612
Clone :
BNI3
Item :
APC anti-human CD152 (CTLA-4)
Isotype :
Mouse IgG2a, κ
Other Names :
CTLA4, Cytotoxic T-Lymphocyte Antigen 4, CTLA-4
Size :
100 tests
Price (USD) :
264 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
Extracellular domain of human CTLA-4 and constant regions of the human IgG heavy chain (CTLA-4/IgG)
Application Notes :
Based on in-house testing, we do not recommend using clone BNI3 for immunohistochemistry of paraffin-embedded tissue section.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA