product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human CD223 (LAG-3)
catalog :
369305
quantity :
25 tests
price :
141 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
11C3C65
reactivity :
human
application :
flow cytometry
more info or order :
citations: 11
Reference
Imai H, Kawase T, Yoshida S, Mese T, Roh S, Fujita A, et al. Peripheral T cell profiling reveals downregulated exhaustion marker and increased diversity in lymphedema post-lymphatic venous anastomosis. iScience. 2023;26:106822 pubmed publisher
Zhong G, Wang Q, Wang Y, Guo Y, Xu M, Guan Y, et al. scRNA-seq reveals ATPIF1 activity in control of T cell antitumor activity. Oncoimmunology. 2022;11:2114740 pubmed publisher
Arasanz H, Bocanegra A, Morilla I, Fern xe1 ndez Irigoyen J, Mart xed nez Aguillo M, Teijeira L, et al. Circulating Low Density Neutrophils Are Associated with Resistance to First Line Anti-PD1/PDL1 Immunotherapy in Non-Small Cell Lung Cancer. Cancers (Basel). 2022;14: pubmed publisher
Qin L, Wang L, Zhang J, Zhou H, Yang Z, Wang Y, et al. Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer. Sci Adv. 2022;8:eabn3774 pubmed publisher
Ando M, Kondo T, Tomisato W, Ito M, Shichino S, Srirat T, et al. Rejuvenating Effector/Exhausted CAR T Cells to Stem Cell Memory-Like CAR T Cells By Resting Them in the Presence of CXCL12 and the NOTCH Ligand. Cancer Res Commun. 2021;1:41-55 pubmed publisher
Edwards C, Sette A, Cox C, Di Fiore B, Wyre C, Sydoruk D, et al. The multi-specific VH-based Humabody CB213 co-targets PD1 and LAG3 on T cells to promote anti-tumour activity. Br J Cancer. 2021;: pubmed publisher
Alenazy M, Saheb Sharif Askari F, Omair M, El Wetidy M, Omair M, Mitwalli H, et al. Abatacept enhances blood regulatory B cells of rheumatoid arthritis patients to a level that associates with disease remittance. Sci Rep. 2021;11:5629 pubmed publisher
Tao L, Farooq M, Gao Y, Zhang L, Niu C, Ajmal I, et al. CD19-CAR-T Cells Bearing a KIR/PD-1-Based Inhibitory CAR Eradicate CD19+HLA-C1- Malignant B Cells While Sparing CD19+HLA-C1+ Healthy B Cells. Cancers (Basel). 2020;12: pubmed publisher
Zheng L, Ren L, Kouhi A, Khawli L, Hu P, Kaslow H, et al. A Humanized Lym-1 CAR with Novel DAP10/DAP12 Signaling Domains Demonstrates Reduced Tonic Signaling and Increased Antitumor Activity in B-Cell Lymphoma Models. Clin Cancer Res. 2020;26:3694-3706 pubmed publisher
Zuazo M, Arasanz H, Fernández Hinojal G, García Granda M, Gato M, Bocanegra A, et al. Functional systemic CD4 immunity is required for clinical responses to PD-L1/PD-1 blockade therapy. EMBO Mol Med. 2019;: pubmed publisher
Yeo L, Woodwyk A, Sood S, Lorenc A, Eichmann M, Pujol Autonell I, et al. Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes. J Clin Invest. 2018;128:3460-3474 pubmed publisher
product information
Antigen :
CD223
Apps. Abbrev. :
FC
Cat # :
369305
Clone :
11C3C65
Item :
PE anti-human CD223 (LAG-3)
Isotype :
Mouse IgG1, κ
Other Names :
CD223, LAG-3, LAG3, lymphocyte-activation gene-3
Size :
25 tests
Price (USD) :
141 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Immunogen :
Human LAG-3 transfected cells.
Application Notes :
The staining of clone 11C3C65 cannot be blocked by clone 7H2C65, which is another anti-human CD223 (LAG-3) antibody.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA