product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Pacific Blue™ anti-human CD45
catalog :
368540
quantity :
100 tests
price :
300 USD
clonality :
monoclonal
host :
mouse
conjugate :
Pacific Blue
clone name :
2D1
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig s1
Poletto E, Colella P, Pimentel Vera L, Khan S, Tomatsu S, Baldo G, et al. Improved engraftment and therapeutic efficacy by human genome-edited hematopoietic stem cells with Busulfan-based myeloablation. Mol Ther Methods Clin Dev. 2022;25:392-409 pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig s1b
Gang E, Kim H, Hsieh Y, Ruan Y, Ogana H, Lee S, et al. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020;136:210-223 pubmed publisher
  • flow cytometry; human; 1:40; loading ...; fig 5j, 5k, s22c
Pellin D, Loperfido M, Baricordi C, Wolock S, Montepeloso A, Weinberg O, et al. A comprehensive single cell transcriptional landscape of human hematopoietic progenitors. Nat Commun. 2019;10:2395 pubmed publisher
Frasca D, Garcia D, Diaz A, Romero M, Thaller S, Blomberg B. Phenotypic and functional features of B cells from two different human subcutaneous adipose depots. PLoS ONE. 2023;18:e0285025 pubmed publisher
Zhang Y, Ma X, Zhao X, Li J, Ma S, Pang Z, et al. AGEs-RAGE-KCa3.1 pathway mediates palmitic acid-induced migration of PBMCs from patients with type 2 diabetes. Heliyon. 2023;9:e14823 pubmed publisher
Wohlgemuth L, Stratmann A, M xfc nnich F, Bernhard S, Thoma xdf B, M xfc nnich F, et al. Modulation of Neutrophil Activity by Soluble Complement Cleavage Products-An In-Depth Analysis. Cells. 2022;11: pubmed publisher
Masuda T, Haji S, Nakashima Y, Tsuda M, Kimura D, Takamatsu A, et al. Identification of a drug-response gene in multiple myeloma through longitudinal single-cell transcriptome sequencing. iScience. 2022;25:104781 pubmed publisher
Tessaro F, Ko E, De Simone M, Piras R, Broz M, Goodridge H, et al. Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity. Cell Rep. 2022;39:110977 pubmed publisher
Frasca D, Romero M, Garcia D, Diaz A, Blomberg B. Obesity Accelerates Age-Associated Defects in Human B Cells Through a Metabolic Reprogramming Induced by the Fatty Acid Palmitate. Front Aging. 2021;2:828697 pubmed publisher
Frasca D, Pallikkuth S, Pahwa S. Metabolic phenotype of B cells from young and elderly HIV individuals. Immun Ageing. 2021;18:35 pubmed publisher
Soto Pantoja D, Gaber M, Arnone A, Bronson S, Cruz Diaz N, Wilson A, et al. Diet Alters Entero-Mammary Signaling to Regulate the Breast Microbiome and Tumorigenesis. Cancer Res. 2021;81:3890-3904 pubmed publisher
Frasca D, Diaz A, Romero M, Blomberg B. Phenotypic and Functional Characterization of Double Negative B Cells in the Blood of Individuals With Obesity. Front Immunol. 2021;12:616650 pubmed publisher
Frasca D, Romero M, Diaz A, Garcia D, Thaller S, Blomberg B. B Cells with a Senescent-Associated Secretory Phenotype Accumulate in the Adipose Tissue of Individuals with Obesity. Int J Mol Sci. 2021;22: pubmed publisher
Scharenberg S, Poletto E, Lucot K, Colella P, Sheikali A, Montine T, et al. Engineering monocyte/macrophage-specific glucocerebrosidase expression in human hematopoietic stem cells using genome editing. Nat Commun. 2020;11:3327 pubmed publisher
Kosaric N, Srifa W, Bonham C, Kiwanuka H, Chen K, Kuehlmann B, et al. Macrophage Subpopulation Dynamics Shift following Intravenous Infusion of Mesenchymal Stromal Cells. Mol Ther. 2020;28:2007-2022 pubmed publisher
Fenton T, Jørgensen P, Niss K, Rubin S, Mörbe U, Riis L, et al. Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity. Immunity. 2020;52:557-570.e6 pubmed publisher
Frasca D, Diaz A, Romero M, Thaller S, Blomberg B. Metabolic requirements of human pro-inflammatory B cells in aging and obesity. PLoS ONE. 2019;14:e0219545 pubmed publisher
Frasca D, Diaz A, Romero M, Thaller S, Blomberg B. Secretion of autoimmune antibodies in the human subcutaneous adipose tissue. PLoS ONE. 2018;13:e0197472 pubmed publisher
product information
Antigen :
CD45
Apps. Abbrev. :
FC
Cat # :
368540
Clone :
2D1
Item :
Pacific Blue™ anti-human CD45
Isotype :
Mouse IgG1, κ
Other Names :
Leukocyte Common Antigen (LCA), T200
Size :
100 tests
Price (USD) :
300 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PB
Immunogen :
Human PBMC
Application Notes :
It was found that the HI30 clone and the 2D1 clone can cross block each other's binding.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA