product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD45
catalog :
368511
quantity :
25 tests
price :
78 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
2D1
reactivity :
human
application :
flow cytometry
more info or order :
citations: 35
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s6c
Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al. Spatiotemporal immune zonation of the human kidney. Science. 2019;365:1461-1466 pubmed publisher
Campbell K, Colacino J, Puttabyatappa M, Dou J, Elkin E, Hammoud S, et al. Placental cell type deconvolution reveals that cell proportions drive preeclampsia gene expression differences. Commun Biol. 2023;6:264 pubmed publisher
Issa N, Bjeije H, Wilson E, Krishnan A, Dunuwille W, Parsons T, et al. KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress. Leukemia. 2023;37:728-740 pubmed publisher
Voit R, Tao L, Yu F, Cato L, Cohen B, Fleming T, et al. A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia. Nat Immunol. 2023;24:69-83 pubmed publisher
Park J, Jo S, Lee M, Kim T, Sung I, Lee J. Comparison of ligamentization potential between anterior cruciate ligament-derived cells and adipose-derived mesenchymal stem cells reseeded to acellularized tendon allograft. Bone Joint Res. 2022;11:777-786 pubmed publisher
Yoshida R, Saigi M, Tani T, Springer B, Shibata H, Kitajima S, et al. MET-Induced CD73 Restrains STING-Mediated Immunogenicity of EGFR-Mutant Lung Cancer. Cancer Res. 2022;82:4079-4092 pubmed publisher
Lee C, Chen Y, Hsiao A, Wang A, Shen O, Wang B, et al. Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells. J Adv Res. 2022;39:73-88 pubmed publisher
Chijimatsu R, Takeda T, Tsuji S, Sasaki K, Kato K, Kojima R, et al. Development of hydroxyapatite-coated nonwovens for efficient isolation of somatic stem cells from adipose tissues. Regen Ther. 2022;21:52-61 pubmed publisher
Galán Díez M, Borot F, Ali A, Zhao J, Gil Iturbe E, Shan X, et al. Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia. Cancer Discov. 2022;12:1106-1127 pubmed publisher
Kim J, Zhang T, Carmona C, Lee B, Seet C, Kostelny M, et al. Latency reversal plus natural killer cells diminish HIV reservoir in vivo. Nat Commun. 2022;13:121 pubmed publisher
Qian S, Huang Q, Chen R, Mo J, Zhou L, Zhao Y, et al. Single-Cell RNA Sequencing Identifies New Inflammation-Promoting Cell Subsets in Asian Patients With Chronic Periodontitis. Front Immunol. 2021;12:711337 pubmed publisher
Choi J, Jang Y, Dabrowska C, Iich E, Evans K, Hall H, et al. Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration. Nat Cell Biol. 2021;23:953-966 pubmed publisher
Wegner J, Zillinger T, Schlee Guimaraes T, Bartok E, Schlee M. An epigenetic GPI anchor defect impairs TLR4 signaling in the B cell transdifferentiation model for primary human monocytes BLaER1. Sci Rep. 2021;11:14983 pubmed publisher
Chen D, Xia S, Zhang R, Li Y, Famulare C, Fan H, et al. Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells. Mol Cell. 2021;: pubmed publisher
Celik H, Krug E, Zhang C, Han W, Issa N, Koh W, et al. A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms. Cancer Discov. 2021;11:3126-3141 pubmed publisher
Govaerts I, Prieto C, Vandersmissen C, Gielen O, Jacobs K, Provost S, et al. PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia. J Hematol Oncol. 2021;14:97 pubmed publisher
Lee J, Jo S, Lee Y, Weon S, Song J, Sung I, et al. Effect of Muscle Cell Preservation on Viability and Differentiation of Hamstring Tendon Graft In Vitro. Cells. 2021;10: pubmed publisher
Jiang S, Tian G, Yang Z, Gao X, Wang F, Li J, et al. Enhancement of acellular cartilage matrix scaffold by Wharton's jelly mesenchymal stem cell-derived exosomes to promote osteochondral regeneration. Bioact Mater. 2021;6:2711-2728 pubmed publisher
Li J, Lin Q, Lin Y, Lai R, Zhang W. Effects of DLX3 on the osteogenic differentiation of induced pluripotent stem cell‑derived mesenchymal stem cells. Mol Med Rep. 2021;23: pubmed publisher
Marinaccio C, Suraneni P, Celik H, Volk A, Wen Q, Ling T, et al. LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms. Cancer Discov. 2021;11:1398-1410 pubmed publisher
Liu S, Wu M, Lancelot M, Deng J, Gao Y, Roback J, et al. BMI1 enables extensive expansion of functional erythroblasts from human peripheral blood mononuclear cells. Mol Ther. 2021;: pubmed publisher
Boyd D, Allen E, Randolph A, Guo X, Weng Y, Sanders C, et al. Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020;587:466-471 pubmed publisher
Zhou Y, Bian S, Zhou X, Cui Y, Wang W, Wen L, et al. Single-Cell Multiomics Sequencing Reveals Prevalent Genomic Alterations in Tumor Stromal Cells of Human Colorectal Cancer. Cancer Cell. 2020;38:818-828.e5 pubmed publisher
Antonucci L, Porcu C, Timperi E, Santini S, Iannucci G, Balsano C. Circulating Neutrophils of Nonalcoholic Steatohepatitis Patients Show an Activated Phenotype and Suppress T Lymphocytes Activity. J Immunol Res. 2020;2020:4570219 pubmed publisher
Wang J, Li Y, Wang P, Han G, Zhang T, Chang J, et al. Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis. Cell Stem Cell. 2020;27:81-97.e8 pubmed publisher
Lin K, Rutter J, Xie A, Pardieu B, Winn E, Bello R, et al. Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer. Nat Genet. 2020;52:408-417 pubmed publisher
Yang X, Cheng X, Tang Y, Qiu X, Wang Y, Kang H, et al. Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure. Immunity. 2019;51:983-996.e6 pubmed publisher
Krivtsov A, Evans K, Gadrey J, Eschle B, Hatton C, Uckelmann H, et al. A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia. Cancer Cell. 2019;36:660-673.e11 pubmed publisher
Mahajan A, Grüneboom A, Petru L, Podolska M, Kling L, Maueröder C, et al. Frontline Science: Aggregated neutrophil extracellular traps prevent inflammation on the neutrophil-rich ocular surface. J Leukoc Biol. 2019;105:1087-1098 pubmed publisher
Celik H, Koh W, Kramer A, Ostrander E, Mallaney C, Fisher D, et al. JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells. Cancer Cell. 2018;34:741-756.e8 pubmed publisher
Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, et al. SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. Cell Stem Cell. 2018;23:355-369.e9 pubmed publisher
Azizi E, Carr A, Plitas G, Cornish A, Konopacki C, Prabhakaran S, et al. Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment. Cell. 2018;174:1293-1308.e36 pubmed publisher
Hansen I, Krabbendam L, Bernink J, Loayza Puch F, Hoepel W, van Burgsteden J, et al. FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming. Nat Commun. 2018;9:863 pubmed publisher
Gao P, Han P, Jiang D, Yang S, Cui Q, Li Z. Effects of the donor age on proliferation, senescence and osteogenic capacity of human urine-derived stem cells. Cytotechnology. 2017;69:751-763 pubmed publisher
Dou D, Calvanese V, Sierra M, Nguyen A, Minasian A, Saarikoski P, et al. Medial HOXA genes demarcate haematopoietic stem cell fate during human development. Nat Cell Biol. 2016;18:595-606 pubmed publisher
product information
Antigen :
CD45
Apps. Abbrev. :
FC
Cat # :
368511
Clone :
2D1
Item :
APC anti-human CD45
Isotype :
Mouse IgG1, κ
Other Names :
Leukocyte Common Antigen (LCA), T200
Size :
25 tests
Price (USD) :
78 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
Human PBMC
Application Notes :
It was found that the HI30 clone and the 2D1 clone can cross block each other's binding.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA