product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 488 anti-human CD11a/CD18 (LFA-1)
catalog :
363404
quantity :
100 tests
price :
323 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
m24
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s1
Matsumoto K, Kurasawa T, Yoshimoto K, Suzuki K, Takeuchi T. Identification of neutrophil β2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analyses. Arthritis Res Ther. 2021;23:136 pubmed publisher
  • flow cytometry; human; 1:200; loading ...; fig 7f
Azcutia V, Kelm M, Luissint A, Boerner K, Flemming S, Quirós M, et al. Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo. Mucosal Immunol. 2020;: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 7b
Murugesan S, Hong J, Yi J, Li D, Beach J, Shao L, et al. Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse. J Cell Biol. 2016;215:383-399 pubmed
Chen M, Li Y, Wu Y, Xie S, Ma J, Yue J, et al. Anti-Tumor Activity of Expanded PBMC-Derived NK Cells by Feeder-Free Protocol in Ovarian Cancer. Cancers (Basel). 2021;13: pubmed publisher
Bezverbnaya K, Moogk D, Cummings D, Baker C, Aarts C, Denisova G, et al. Development of a B-cell maturation antigen-specific T-cell antigen coupler receptor for multiple myeloma. Cytotherapy. 2021;23:820-832 pubmed publisher
Fan Z, Mikulski Z, McArdle S, Sundd P, Ley K. Super-STORM: Molecular Modeling to Achieve Single-molecule Localization with STORM Microscopy. STAR Protoc. 2020;1:100012 pubmed publisher
Weulersse M, Asrir A, Pichler A, Lemaitre L, Braun M, Carrié N, et al. Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy. Immunity. 2020;53:824-839.e10 pubmed publisher
Mancuso R, Casper J, Schmidt A, Krahenbuhl S, Weitz Schmidt G. Anti-αLβ2 antibodies reveal novel endocytotic cross-modulatory functionality. Br J Pharmacol. 2020;177:2696-2711 pubmed publisher
Chen E, Tay N, Brzostek J, Gascoigne N, Rybakin V. A Dual Inhibitor of Cdc7/Cdk9 Potently Suppresses T Cell Activation. Front Immunol. 2019;10:1718 pubmed publisher
Wilton K, Overlee B, Billadeau D. NKG2D/DAP10 Signaling recruits EVL to the cytotoxic synapse to generate F-actin and promote NK cell cytotoxicity. J Cell Sci. 2019;: pubmed publisher
Fan Z, Kiosses W, Sun H, Orecchioni M, Ghosheh Y, Zajonc D, et al. High-Affinity Bent β2-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis. Cell Rep. 2019;26:119-130.e5 pubmed publisher
product information
Antigen :
CD18
Apps. Abbrev. :
FC
Cat # :
363404
Clone :
m24
Item :
Alexa Fluor® 488 anti-human CD11a/CD18 (LFA-1)
Isotype :
Mouse IgG1, κ
Other Names :
Integrin β2 subunit, LFA -1 β subunit, β2 integrin, b2 subunit, LFA-1b, LFA-1 beta, LFA1b, LFA1 beta, beta 2 integrin subunit LFA
Size :
100 tests
Price (USD) :
323 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A488
Immunogen :
Fibronectin-purified human monocytes
Application Notes :
Clone m24 can be used as a reporter of the activation state of integrin receptor in response to exposure with Mg^2+ or Mn^2+.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA