FITC anti-human CD41/CD61 | BioLegend 362804 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

FITC anti-human CD41/CD61

catalog :

362804

quantity :

100 tests

price :

323 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

PAC-1

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 13

Reference
Iglesias M, Sanchez Rivera L, Ibrahim Kosta M, Naudin C, Munsch G, Goumidi L, et al. Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism. Nat Commun. 2023;14:3280 pubmed publisher
Cano Mendez A, Garc xed a Larragoiti N, Damian Vazquez M, Guzman Cancino P, Lopez Castaneda S, Ochoa Zarzosa A, et al. Platelet Reactivity and Inflammatory Phenotype Induced by Full-Length Spike SARS-CoV-2 Protein and Its RBD Domain. Int J Mol Sci. 2022;23: pubmed publisher
Hajtuch J, Iwicka E, Szczoczarz A, Flis D, Megiel E, Cieci xf3 rski P, et al. The Pharmacological Effects of Silver Nanoparticles Functionalized with Eptifibatide on Platelets and Endothelial Cells. Int J Nanomedicine. 2022;17:4383-4400 pubmed publisher
Marsden A, Riley D, Barry A, Khalil J, Guinn B, Kemp N, et al. Inhibition of Arginine Methylation Impairs Platelet Function. ACS Pharmacol Transl Sci. 2021;4:1567-1577 pubmed publisher
Zhao W, Wei Z, Xin G, Li Y, Yuan J, Ming Y, et al. Piezo1 initiates platelet hyperreactivity and accelerates thrombosis in hypertension. J Thromb Haemost. 2021;19:3113-3125 pubmed publisher
Garcia Larragoiti N, Kim Y, Lopez Camacho C, Cano Mendez A, Lopez Castaneda S, Hernández Hernández D, et al. Platelet activation and aggregation response to dengue virus nonstructural protein 1 and domains. J Thromb Haemost. 2021;: pubmed publisher
Ha K, Zheng X, Kessinger C, Mauskapf A, Li W, Kawamura Y, et al. In Vivo Platelet Detection Using a Glycoprotein IIb/IIIa-Targeted Near-Infrared Fluorescence Imaging Probe. ACS Sens. 2021;6:2225-2232 pubmed publisher
Han P, Hanlon D, Arshad N, Lee J, Tatsuno K, Robinson E, et al. Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes. Sci Adv. 2020;6:eaaz1580 pubmed publisher
Bhat A, Das S, Yadav G, Chaudhary S, Vyas A, Islam M, et al. Hyperoxidized Albumin Modulates Platelets and Promotes Inflammation Through CD36 Receptor in Severe Alcoholic Hepatitis. Hepatol Commun. 2020;4:50-65 pubmed publisher
Lu W, Li J, Chen R, Huang L, Lee T, Lin K. VAS2870 and VAS3947 attenuate platelet activation and thrombus formation via a NOX-independent pathway downstream of PKC. Sci Rep. 2019;9:18852 pubmed publisher
Costa B, Eisemann T, Strelau J, Spaan I, Korshunov A, Liu H, et al. Intratumoral platelet aggregate formation in a murine preclinical glioma model depends on podoplanin expression on tumor cells. Blood Adv. 2019;3:1092-1102 pubmed publisher
Qi Y, Chen W, Liang X, Xu K, Gu X, Wu F, et al. Novel antibodies against GPIbα inhibit pulmonary metastasis by affecting vWF-GPIbα interaction. J Hematol Oncol. 2018;11:117 pubmed publisher
Lien L, Lin K, Huang L, Tseng M, Chiu H, Chen R, et al. Licochalcone A Prevents Platelet Activation and Thrombus Formation through the Inhibition of PLCÎ³2-PKC, Akt, and MAPK Pathways. Int J Mol Sci. 2017;18: pubmed publisher

product information

Antigen :

CD41/CD61

Apps. Abbrev. :

Cat # :

362804

Clone :

PAC-1

Item :

FITC anti-human CD41/CD61

Isotype :

Mouse IgM, κ

Other Names :

gpIIb/IIIa complex, integrin αIIbβ3

Size :

100 tests

Price (USD) :

323 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

FITC

Immunogen :

Human platelets

Application Notes :

Additional reported applications (for the relevant formats of this clone) include: immunoprecipitation^1,2, Western blotting^2 and in vitro blocking of platelet aggregation^2.; The PAC-1 antibody reacts with activation-induced conformational epitope of the integrin aIIbß3. PAC-1 binding to fibrinogen is pH and Ca^2+ dependent, and will not bind to platelets that have been fixed. We recommend staining in buffers free of Ethylenediaminetetraacetic acid (EDTA) at a pH of 6.5 or higher. Sodium citrate may be used as an anticoagulant for blood collection^3.;

more info or order :

BioLegend product webpage