Purified anti-human CD41/CD61 | BioLegend 362802 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human CD41/CD61

catalog :

362802

quantity :

100 μg

price :

229 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PAC-1

reactivity :

human

application :

western blot, immunoprecipitation, flow cytometry

more info or order :

BioLegend product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 1	Deng W, Xu Y, Chen W, Paul D, Syed A, Dragovich M, et al. Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor. Nat Commun. 2016;7:12863 pubmed publisher
	Zhang L, Zhu Y, Wei X, Chen X, Li Y, Zhu Y, et al. Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model. Acta Pharm Sin B. 2022;12:3427-3447 pubmed publisher
	Zhu Y, Smith D, Zhou Y, Li Y, Yu J, Lee D, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019;25:542-557.e9 pubmed publisher
	Srinivasan S, Schiemer J, Zhang X, Chishti A, Le Breton G. GÎ±13 Switch Region 2 Binds to the Talin Head Domain and Activates Î±IIbÎ²3 Integrin in Human Platelets. J Biol Chem. 2015;290:25129-39 pubmed publisher

product information

Antigen :

CD41/CD61

Apps. Abbrev. :

FC, IP, WB

Cat # :

362802

Clone :

PAC-1

Item :

Purified anti-human CD41/CD61

Isotype :

Mouse IgM, κ

Other Names :

gpIIb/IIIa complex, integrin αIIbβ3

Size :

100 μg

Price (USD) :

229 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

Human platelets

Application Notes :

Additional reported applications (for the relevant formats of this clone) include: immunoprecipitation^1,2, Western blotting^2 and in vitro blocking of platelet aggregation^2.; The PAC-1 antibody reacts with activation-induced conformational epitope of the integrin aIIbß3. PAC-1 binding to fibrinogen is pH and Ca^2+ dependent, and will not bind to platelets that have been fixed. We recommend staining in buffers free of Ethylenediaminetetraacetic acid (EDTA) at a pH of 6.5 or higher. Sodium citrate may be used as an anticoagulant for blood collection^3.;

more info or order :

BioLegend product webpage