Ultra-LEAF™ Purified anti-human/mouse/rat MR1 | BioLegend 361109 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-human/mouse/rat MR1

catalog :

361109

quantity :

100 μg

price :

182 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

26.5

reactivity :

human, mouse, rat

application :

ELISA, neutralization, immunoprecipitation, flow cytometry, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; fig 3a	Crowther M, Dolton G, Legut M, Caillaud M, Lloyd A, Attaf M, et al. Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nat Immunol. 2020;21:178-185 pubmed publisher
	Mabire M, Hegde P, Hammoutene A, Wan J, Ca xeb r C, Sayegh R, et al. MAIT cell inhibition promotes liver fibrosis regression via macrophage phenotype reprogramming. Nat Commun. 2023;14:1830 pubmed publisher
	Sugimoto C, Murakami Y, Ishii E, Fujita H, Wakao H. Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activity. elife. 2022;11: pubmed publisher
	Jiang G, Shi L, Zheng X, Zhang X, Wu K, Liu B, et al. Androgen receptor affects the response to immune checkpoint therapy by suppressing PD-L1 in hepatocellular carcinoma. Aging (Albany NY). 2020;12:11466-11484 pubmed publisher

product information

Antigen :

MR1

Apps. Abbrev. :

FC, ELISA, IP, Block

Cat # :

361109

Clone :

26.5

Item :

Ultra-LEAF™ Purified anti-human/mouse/rat MR1

Isotype :

Mouse IgG2a, κ

Other Names :

Major Histocompatibility Complex Class I-related, HLALS

Size :

100 μg

Price (USD) :

182 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ULEAF

Immunogen :

Soluble complexes of MR1 ectodomain and B2M.

Application Notes :

Additional reported applications for the relevant formats include: blocking MR1-dependent activation of MAIT hybridomas, clones, or MAIT TCR-transduced cell lines^1-6, detection of folded MR1 conformers^3,7, and immunoprecipitation of MR1 from cell lysates^7.;

more info or order :

BioLegend product webpage