PE anti-human/mouse/rat MR1 | BioLegend 361105 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human/mouse/rat MR1

catalog :

361105

quantity :

25 tests

price :

153 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

26.5

reactivity :

human, mouse, rat

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 5

Reference
Mabire M, Hegde P, Hammoutene A, Wan J, Ca xeb r C, Sayegh R, et al. MAIT cell inhibition promotes liver fibrosis regression via macrophage phenotype reprogramming. Nat Commun. 2023;14:1830 pubmed publisher
Souter M, Awad W, Li S, Pediongco T, Meehan B, Meehan L, et al. CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells. J Exp Med. 2022;219: pubmed publisher
Tang J, Cait A, White R, Arabshahi H, O Sullivan D, Gasser O. MR1-dependence of unmetabolized folic acid side-effects. Front Immunol. 2022;13:946713 pubmed publisher
McSharry B, Samer C, McWilliam H, Ashley C, Yee M, Steain M, et al. Virus-Mediated Suppression of the Antigen Presentation Molecule MR1. Cell Rep. 2020;30:2948-2962.e4 pubmed publisher
Laugel B, Lloyd A, Meermeier E, Crowther M, Connor T, Dolton G, et al. Engineering of Isogenic Cells Deficient for MR1 with a CRISPR/Cas9 Lentiviral System: Tools To Study Microbial Antigen Processing and Presentation to Human MR1-Restricted T Cells. J Immunol. 2016;197:971-82 pubmed publisher

product information

Antigen :

MR1

Apps. Abbrev. :

Cat # :

361105

Clone :

26.5

Item :

PE anti-human/mouse/rat MR1

Isotype :

Mouse IgG2a, κ

Other Names :

Major Histocompatibility Complex Class I-related, HLALS

Size :

25 tests

Price (USD) :

153 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Immunogen :

Soluble complexes of MR1 ectodomain and B2M.

Application Notes :

Additional reported applications for the relevant formats include: blocking MR1-dependent activation of MAIT hybridomas, clones, or MAIT TCR-transduced cell lines^1-6, detection of folded MR1 conformers^3,7, and immunoprecipitation of MR1 from cell lysates^7.;

more info or order :

BioLegend product webpage