product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human MRGX2
catalog :
359002
quantity :
100 μg
price :
335 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
K125H4
reactivity :
human
application :
flow cytometry
more info or order :
citations: 5
Reference
Lazki Hagenbach P, Kleeblatt E, Ali H, Sagi Eisenberg R. Spatiotemporal Patterns of Substance P-Bound MRGPRX2 Reveal a Novel Connection Between Macropinosome Resolution and Secretory Granule Regeneration in Mast Cells. Front Immunol. 2022;13:892239 pubmed publisher
Chompunud Na Ayudhya C, Amponnawarat A, Ali H. Substance P Serves as a Balanced Agonist for MRGPRX2 and a Single Tyrosine Residue Is Required for β-Arrestin Recruitment and Receptor Internalization. Int J Mol Sci. 2021;22: pubmed publisher
Lazki Hagenbach P, Ali H, Sagi Eisenberg R. Authentic and Ectopically Expressed MRGPRX2 Elicit Similar Mechanisms to Stimulate Degranulation of Mast Cells. Cells. 2021;10: pubmed publisher
Babina M, Wang Z, Franke K, Zuberbier T. Thymic Stromal Lymphopoietin Promotes MRGPRX2-Triggered Degranulation of Skin Mast Cells in a STAT5-Dependent Manner with Further Support from JNK. Cells. 2021;10: pubmed publisher
PLUM T, Wang X, Rettel M, Krijgsveld J, Feyerabend T, Rodewald H. Human Mast Cell Proteome Reveals Unique Lineage, Putative Functions, and Structural Basis for Cell Ablation. Immunity. 2020;52:404-416.e5 pubmed publisher
product information
Antigen :
MRGX2
Apps. Abbrev. :
FC
Cat # :
359002
Clone :
K125H4
Item :
Purified anti-human MRGX2
Isotype :
Mouse IgG2b, κ
Other Names :
Mas-related G-protein coupled receptor member X2, MRGPRX2
Size :
100 μg
Price (USD) :
335 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
DNA vaccine containing the full length gene of human MRGX2
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA