product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human CD138 (Syndecan-1)
catalog :
356502
quantity :
100 μg
price :
138 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MI15
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 5b
Yue X, Petersen F, Shu Y, Kasper B, Magatsin J, Ahmadi M, et al. Transfer of PBMC From SSc Patients Induces Autoantibodies and Systemic Inflammation in Rag2-/-/IL2rg-/- Mice. Front Immunol. 2021;12:677970 pubmed publisher
  • flow cytometry; human; loading ...; fig 4b
Luo B, Zhan Y, Luo M, Dong H, Liu J, Lin Y, et al. Engineering of α-PD-1 antibody-expressing long-lived plasma cells by CRISPR/Cas9-mediated targeted gene integration. Cell Death Dis. 2020;11:973 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1h
Bell L, Lenhart A, Rosenwald A, Monoranu C, Berberich Siebelt F. Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells. Front Immunol. 2019;10:3090 pubmed publisher
  • flow cytometry; human; fig 1a
Lee L, Draper B, Chaplin N, Philip B, Chin M, Galas Filipowicz D, et al. An APRIL-based chimeric antigen receptor for dual targeting of BCMA and TACI in multiple myeloma. Blood. 2018;131:746-758 pubmed publisher
  • flow cytometry; human; loading ...; fig 5a
Tanaka A, Tumkosit U, Nakamura S, Motooka D, Kishishita N, Priengprom T, et al. Genome-Wide Screening Uncovers the Significance of N-Sulfation of Heparan Sulfate as a Host Cell Factor for Chikungunya Virus Infection. J Virol. 2017;91: pubmed publisher
  • flow cytometry; human
Rao D, Gurish M, Marshall J, Slowikowski K, Fonseka C, Liu Y, et al. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017;542:110-114 pubmed publisher
  • flow cytometry; human; fig 6
Lewis M, Vyse S, Shields A, Boeltz S, Gordon P, Spector T, et al. UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases. Am J Hum Genet. 2015;96:221-34 pubmed publisher
Xu C, Yang J, Kosters A, Babcock B, Qiu P, Ghosn E. Comprehensive multi-omics single-cell data integration reveals greater heterogeneity in the human immune system. iScience. 2022;25:105123 pubmed publisher
Alpert A, Nahman O, Starosvetsky E, Hayun M, Curiel T, Ofran Y, et al. Alignment of single-cell trajectories by tuMap enables high-resolution quantitative comparison of cancer samples. Cell Syst. 2022;13:71-82.e8 pubmed publisher
Saygin C, Hu E, Zhang P, Sher S, Lozanski A, Doong T, et al. Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq. Leukemia. 2021;35:3406-3420 pubmed publisher
Thompson E, Cascino K, Ordonez A, Zhou W, Vaghasia A, Hamacher Brady A, et al. Metabolic programs define dysfunctional immune responses in severe COVID-19 patients. Cell Rep. 2021;34:108863 pubmed publisher
Gudjonsson J, Tsoi L, Ma F, Billi A, van Straalen K, Vossen A, et al. Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis. JCI Insight. 2020;5: pubmed publisher
Karlsson J, Nilsson L, Mitra S, Alsén S, Shelke G, Sah V, et al. Molecular profiling of driver events in metastatic uveal melanoma. Nat Commun. 2020;11:1894 pubmed publisher
Nerreter T, Letschert S, Götz R, Doose S, Danhof S, Einsele H, et al. Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T. Nat Commun. 2019;10:3137 pubmed publisher
product information
Antigen :
CD138
Apps. Abbrev. :
FC, ICC, WB, IHC-P, SB
Cat # :
356502
Clone :
MI15
Item :
Purified anti-human CD138 (Syndecan-1)
Isotype :
Mouse IgG1, κ
Other Names :
B-B4
Size :
100 μg
Price (USD) :
138 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
A mixture of U266 and XG-1 human myeloma cell lines.
Application Notes :
The epitope recognized by MI15 is found within the ectodomain of the CD138 core protein. It has been reported that MI15 blocks the binding of clone B-B4 but not clone DL-101 by flow cytometric analysis. Clones DL-101 and MI15 exhibit differential staining patterns on in vitro generated plasma cells and some CD138^+ cell lines.^4Additional reported applications for the relevant formats include: immunofluorescent staining^1, Western blotting^2, immunohistochemical staining of formalin-fixed paraffin-embedded frozen tissue sections^3, and spatial biology (IBEX)^5,6.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA