product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 488 anti-human EGFR
catalog :
352907
quantity :
25 tests
price :
129 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
AY13
reactivity :
human
application :
immunocytochemistry, flow cytometry, other
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • other; human; 1:100; loading ...
Leelatian N, Sinnaeve J, Mistry A, Barone S, Brockman A, Diggins K, et al. Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells. elife. 2020;9: pubmed publisher
  • flow cytometry; human; loading ...; fig 2c
Mahameed M, Boukeileh S, Obiedat A, Darawshi O, Dipta P, Rimon A, et al. Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy. Nat Commun. 2020;11:1304 pubmed publisher
  • flow cytometry; human; loading ...; fig 1c
Seitz C, Schroeder S, Knopf P, Krahl A, Hau J, Schleicher S, et al. GD2-targeted chimeric antigen receptor T cells prevent metastasis formation by elimination of breast cancer stem-like cells. Oncoimmunology. 2020;9:1683345 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Zhang Z, Le K, La Placa D, Armstrong B, Miller M, Shively J. CXCR2 specific endocytosis of immunomodulatory peptide LL-37 in human monocytes and formation of LL-37 positive large vesicles in differentiated monoosteophils. Bone Rep. 2020;12:100237 pubmed publisher
Subham S, Jeppson J, Worcester C, Schatmeyer B, Zhao J, Madan R, et al. EGFR as a potent CAR T target in triple negative breast cancer brain metastases. Breast Cancer Res Treat. 2023;197:57-69 pubmed publisher
Staudte S, Klinghammer K, Jurmeister P, Jank P, Blohmer J, Liebs S, et al. Multiparametric Phenotyping of Circulating Tumor Cells for Analysis of Therapeutic Targets, Oncogenic Signaling Pathways and DNA Repair Markers. Cancers (Basel). 2022;14: pubmed publisher
Jayasinghe M, Pirisinu M, Yang Y, Peng B, Pham T, Lee C, et al. Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy. Theranostics. 2022;12:3288-3315 pubmed publisher
Marrocco I, Romaniello D, Vaknin I, Drago García D, Oren R, Uribe M, et al. Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models. EMBO Mol Med. 2021;13:e13144 pubmed publisher
Kitamura Y, Kanaya N, Moleirinho S, Du W, Reinshagen C, Attia N, et al. Anti-EGFR VHH-armed death receptor ligand-engineered allogeneic stem cells have therapeutic efficacy in diverse brain metastatic breast cancers. Sci Adv. 2021;7: pubmed publisher
Pham T, Jayasinghe M, Pham T, Yang Y, Wei L, Usman W, et al. Covalent conjugation of extracellular vesicles with peptides and nanobodies for targeted therapeutic delivery. J Extracell Vesicles. 2021;10:e12057 pubmed publisher
Liu H, Paddock M, Wang H, Murphy C, Geck R, Navarro A, et al. The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer. Cancer Discov. 2020;10:1226-1239 pubmed publisher
Xuan Z, Zhao L, Li Z, Song W, Chen J, Chen J, et al. EPS8L3 promotes hepatocellular carcinoma proliferation and metastasis by modulating EGFR dimerization and internalization. Am J Cancer Res. 2020;10:60-77 pubmed
Jiao S, Subudhi S, Aparicio A, Ge Z, Guan B, Miura Y, et al. Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy. Cell. 2019;179:1177-1190.e13 pubmed publisher
Salvany Celades M, van der Zwan A, Benner M, Setrajcic Dragos V, Bougleux Gomes H, Iyer V, et al. Three Types of Functional Regulatory T Cells Control T Cell Responses at the Human Maternal-Fetal Interface. Cell Rep. 2019;27:2537-2547.e5 pubmed publisher
Mahameed M, Wilhelm T, Darawshi O, Obiedat A, Tommy W, Chintha C, et al. The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors. Cell Death Dis. 2019;10:300 pubmed publisher
Leonard B, Brand T, O Keefe R, Lee E, Zeng Y, Kemmer J, et al. BET Inhibition Overcomes Receptor Tyrosine Kinase-Mediated Cetuximab Resistance in HNSCC. Cancer Res. 2018;78:4331-4343 pubmed publisher
Arshad N, Cresswell P. Tumor-associated calreticulin variants functionally compromise the peptide loading complex and impair its recruitment of MHC-I. J Biol Chem. 2018;293:9555-9569 pubmed publisher
Assad Kahn S, Costa S, Gholamin S, Nitta R, Dubois L, Fève M, et al. The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway. EMBO Mol Med. 2016;8:511-26 pubmed publisher
product information
Antigen :
EGFR
Apps. Abbrev. :
FC, ICC
Cat # :
352907
Clone :
AY13
Item :
Alexa Fluor® 488 anti-human EGFR
Isotype :
Mouse IgG1, κ
Other Names :
Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, HER1
Size :
25 tests
Price (USD) :
129 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A488
Immunogen :
Non-small cell lung cancer (NSCLC) cell line NCI-H322
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA