product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human EGFR
catalog :
352906
quantity :
100 tests
price :
338 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
AY13
reactivity :
human
application :
flow cytometry
more info or order :
citations: 25
Reference
Urak R, Gittins B, Soemardy C, Grepo N, Goldberg L, Maker M, et al. Evaluation of the Elements of Short Hairpin RNAs in Developing shRNA-Containing CAR T Cells. Cancers (Basel). 2023;15: pubmed publisher
Yu J, Feng H, Sang Q, Li F, Chen M, Yu B, et al. VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer. EBioMedicine. 2023;89:104451 pubmed publisher
Yamaguchi Y, Gibson J, Ou K, Lopez L, Ng R, Leggett N, et al. PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophages. J Immunother Cancer. 2022;10: pubmed publisher
Jang H, Lee H, Yu W, Ramineni M, Truong C, Ramos D, et al. Therapeutic Targeting of Macrophage Plasticity Remodels the Tumor-Immune Microenvironment. Cancer Res. 2022;82:2593-2609 pubmed publisher
Dong C, Fu S, Karvas R, Chew B, Fischer L, Xing X, et al. A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells. Nat Commun. 2022;13:2548 pubmed publisher
Au J, Requena D, Rishik H, Kallol S, Tekkatte C, Farah O, et al. Role of autocrine bone morphogenetic protein Signaling in trophoblast stem cells. Biol Reprod. 2021;: pubmed publisher
Niu M, Xu J, Liu Y, Li Y, He T, Ding L, et al. FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth. Nat Commun. 2021;12:5919 pubmed publisher
Morey R, Farah O, Kallol S, Requena D, Meads M, Moretto Zita M, et al. Transcriptomic Drivers of Differentiation, Maturation, and Polyploidy in Human Extravillous Trophoblast. Front Cell Dev Biol. 2021;9:702046 pubmed publisher
Yerneni S, Werner S, Azambuja J, Ludwig N, Eutsey R, Aggarwal S, et al. Pneumococcal Extracellular Vesicles Modulate Host Immunity. MBio. 2021;12:e0165721 pubmed publisher
Khan S, Park K, Fischer L, Dong C, Lungjangwa T, Jimenez M, et al. Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening. Cell Rep. 2021;35:109233 pubmed publisher
Horii M, Morey R, Bui T, Touma O, Nelson K, Cho H, et al. Modeling preeclampsia using human induced pluripotent stem cells. Sci Rep. 2021;11:5877 pubmed publisher
Song J, Liu Y, Liu F, Zhang L, Li G, Yuan C, et al. The 14-3-3σ protein promotes HCC anoikis resistance by inhibiting EGFR degradation and thereby activating the EGFR-dependent ERK1/2 signaling pathway. Theranostics. 2021;11:996-1015 pubmed publisher
Sreevalsan S, Döring M, Paszkowski Rogacz M, Brux M, Blanck C, Meyer M, et al. MLLT6 maintains PD-L1 expression and mediates tumor immune resistance. EMBO Rep. 2020;:e50155 pubmed publisher
Ludwig N, Yerneni S, Azambuja J, Gillespie D, Menshikova E, Jackson E, et al. Tumor-derived exosomes promote angiogenesis via adenosine A2B receptor signaling. Angiogenesis. 2020;23:599-610 pubmed publisher
Ho J, Yang X, Nikou S, Kichik N, Donkin A, Ponde N, et al. Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor. Nat Commun. 2019;10:2297 pubmed publisher
Xu X, Liu Q, Zhang C, Ren S, Xu L, Zhao Z, et al. Inhibition of DYRK1A-EGFR axis by p53-MDM2 cascade mediates the induction of cellular senescence. Cell Death Dis. 2019;10:282 pubmed publisher
Dong Y, Ding Y, Guo W, Huang J, Yang Z, Zhang Y, et al. The functional verification of EGFR-CAR T-cells targeted to hypopharyngeal squamous cell carcinoma. Onco Targets Ther. 2018;11:7053-7059 pubmed publisher
Al Akhrass H, Naves T, Vincent F, Magnaudeix A, Durand K, Bertin F, et al. Sortilin limits EGFR signaling by promoting its internalization in lung cancer. Nat Commun. 2017;8:1182 pubmed publisher
Halim L, Romano M, McGregor R, Correa I, Pavlidis P, Grageda N, et al. An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment. Cell Rep. 2017;20:757-770 pubmed publisher
Bak R, Porteus M. CRISPR-Mediated Integration of Large Gene Cassettes Using AAV Donor Vectors. Cell Rep. 2017;20:750-756 pubmed publisher
Horii M, Li Y, Wakeland A, Pizzo D, Nelson K, Sabatini K, et al. Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease. Proc Natl Acad Sci U S A. 2016;113:E3882-91 pubmed publisher
Okita R, Wolf D, Yasuda K, Maeda A, Yukawa T, Saisho S, et al. Contrasting Effects of the Cytotoxic Anticancer Drug Gemcitabine and the EGFR Tyrosine Kinase Inhibitor Gefitinib on NK Cell-Mediated Cytotoxicity via Regulation of NKG2D Ligand in Non-Small-Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0139809 pubmed publisher
Dong A, Wodziak D, Lowe A. Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface. J Biol Chem. 2015;290:8016-27 pubmed publisher
Pasternack J, Domogauer J, Khullar A, Akudugu J, Howell R. The advantage of antibody cocktails for targeted alpha therapy depends on specific activity. J Nucl Med. 2014;55:2012-9 pubmed publisher
Li Y, Moretto Zita M, Soncin F, Wakeland A, Wolfe L, Leon Garcia S, et al. BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ?Np63+ cytotrophoblast stem cell state. Development. 2013;140:3965-76 pubmed publisher
product information
Antigen :
EGFR
Apps. Abbrev. :
FC
Cat # :
352906
Clone :
AY13
Item :
APC anti-human EGFR
Isotype :
Mouse IgG1, κ
Other Names :
Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, HER1
Size :
100 tests
Price (USD) :
338 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
Non-small cell lung cancer (NSCLC) cell line NCI-H322
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA