product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human EGFR
catalog :
352903
quantity :
25 tests
price :
117 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
AY13
reactivity :
human
application :
flow cytometry
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1d
Kitamura Y, Kanaya N, Moleirinho S, Du W, Reinshagen C, Attia N, et al. Anti-EGFR VHH-armed death receptor ligand-engineered allogeneic stem cells have therapeutic efficacy in diverse brain metastatic breast cancers. Sci Adv. 2021;7: pubmed publisher
  • flow cytometry; human; loading ...; fig 1c
Seitz C, Schroeder S, Knopf P, Krahl A, Hau J, Schleicher S, et al. GD2-targeted chimeric antigen receptor T cells prevent metastasis formation by elimination of breast cancer stem-like cells. Oncoimmunology. 2020;9:1683345 pubmed publisher
  • flow cytometry; human; fig 4A
Edinger N, Lebendiker M, Klein S, Zigler M, Langut Y, Levitzki A. Targeting polyIC to EGFR over-expressing cells using a dsRNA binding protein domain tethered to EGF. PLoS ONE. 2016;11:e0162321 pubmed publisher
Jacquot P, Mu xf1 oz Garcia J, Fleury M, Cochonneau D, Gaussin R, Enouf E, et al. Engineering of a Bispecific Nanofitin with Immune Checkpoint Inhibitory Activity Conditioned by the Cross-Arm Binding to EGFR and PDL1. Biomolecules. 2023;13: pubmed publisher
Jo D, Kaczmarek S, Shin O, Wang L, Cowan J, McComb S, et al. Simultaneous engineering of natural killer cells for CAR transgenesis and CRISPR-Cas9 knockout using retroviral particles. Mol Ther Methods Clin Dev. 2023;29:173-184 pubmed publisher
An L, Wang Y, Wu G, Wang Z, Shi Z, Liu C, et al. Defining the sensitivity landscape of EGFR variants to tyrosine kinase inhibitors. Transl Res. 2023;255:14-25 pubmed publisher
Quijano Rubio A, Bhuiyan A, Yang H, Leung I, Bello E, Ali L, et al. A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy. Nat Biotechnol. 2023;41:532-540 pubmed publisher
Cheng C, Cui H, Liu H, Wu Y, Ding N, Weng Y, et al. Role of Epidermal Growth Factor Receptor-Specific CAR-T Cells in the Suppression of Esophageal Squamous Cell Carcinoma. Cancers (Basel). 2022;14: pubmed publisher
Wang J, Lee W, Fang C, Hsu H, Chen B, Liu H. Human Papillomavirus Oncoproteins Confer Sensitivity to Cisplatin by Interfering with Epidermal Growth Factor Receptor Nuclear Trafficking Related to More Favorable Clinical Survival Outcomes in Non-Small Cell Lung Cancer. Cancers (Basel). 2022;14: pubmed publisher
Carnevale J, Shifrut E, Kale N, Nyberg W, Blaeschke F, Chen Y, et al. RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature. 2022;609:174-182 pubmed publisher
Jayasinghe M, Pirisinu M, Yang Y, Peng B, Pham T, Lee C, et al. Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy. Theranostics. 2022;12:3288-3315 pubmed publisher
Lu T, Ma R, Dong W, Teng K, Kollath D, Li Z, et al. Off-the-shelf CAR natural killer cells secreting IL-15 target spike in treating COVID-19. Nat Commun. 2022;13:2576 pubmed publisher
Brohl A, Sindiri S, Wei J, Milewski D, Chou H, Song Y, et al. Immuno-transcriptomic profiling of extracranial pediatric solid malignancies. Cell Rep. 2021;37:110047 pubmed publisher
Li G, Guo J, Zheng Y, Ding W, Han Z, Qin L, et al. CXCR5 guides migration and tumor eradication of anti-EGFR chimeric antigen receptor T cells. Mol Ther Oncolytics. 2021;22:507-517 pubmed publisher
Okada R, Furusawa A, Vermeer D, Inagaki F, Wakiyama H, Kato T, et al. Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials. EBioMedicine. 2021;67:103345 pubmed publisher
Fischer A, Wolf I, Fuchs H, Masilamani A, Wolf P. Pseudomonas Exotoxin A Based Toxins Targeting Epidermal Growth Factor Receptor for the Treatment of Prostate Cancer. Toxins (Basel). 2020;12: pubmed publisher
Sreevalsan S, Döring M, Paszkowski Rogacz M, Brux M, Blanck C, Meyer M, et al. MLLT6 maintains PD-L1 expression and mediates tumor immune resistance. EMBO Rep. 2020;:e50155 pubmed publisher
Leelatian N, Sinnaeve J, Mistry A, Barone S, Brockman A, Diggins K, et al. Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells. elife. 2020;9: pubmed publisher
Ahn S, Li J, Sun C, Gao K, Hirabayashi K, Li H, et al. Cancer Immunotherapy with T Cells Carrying Bispecific Receptors That Mimic Antibodies. Cancer Immunol Res. 2019;7:773-783 pubmed publisher
Aldeghaither D, Zahavi D, Murray J, Fertig E, Graham G, Zhang Y, et al. A Mechanism of Resistance to Antibody-Targeted Immune Attack. Cancer Immunol Res. 2019;7:230-243 pubmed publisher
Wing A, Fajardo C, Posey A, Shaw C, Da T, Young R, et al. Improving CART-Cell Therapy of Solid Tumors with Oncolytic Virus-Driven Production of a Bispecific T-cell Engager. Cancer Immunol Res. 2018;6:605-616 pubmed publisher
Han X, Cinay G, Zhao Y, Guo Y, Zhang X, Wang P. Adnectin-Based Design of Chimeric Antigen Receptor for T Cell Engineering. Mol Ther. 2017;25:2466-2476 pubmed publisher
Halim L, Romano M, McGregor R, Correa I, Pavlidis P, Grageda N, et al. An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment. Cell Rep. 2017;20:757-770 pubmed publisher
Bak R, Porteus M. CRISPR-Mediated Integration of Large Gene Cassettes Using AAV Donor Vectors. Cell Rep. 2017;20:750-756 pubmed publisher
Jarantow S, Bushey B, Pardinas J, Boakye K, Lacy E, Sanders R, et al. Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor × c-MET Bispecific Antibody. J Biol Chem. 2015;290:24689-704 pubmed publisher
Wang Y, Zhou J, Qiu L, Wang X, Chen L, Liu T, et al. Cisplatin-alginate conjugate liposomes for targeted delivery to EGFR-positive ovarian cancer cells. Biomaterials. 2014;35:4297-309 pubmed publisher
Grass G, Tolliver L, Bratoeva M, Toole B. CD147, CD44, and the epidermal growth factor receptor (EGFR) signaling pathway cooperate to regulate breast epithelial cell invasiveness. J Biol Chem. 2013;288:26089-104 pubmed publisher
product information
Antigen :
EGFR
Apps. Abbrev. :
FC
Cat # :
352903
Clone :
AY13
Item :
PE anti-human EGFR
Isotype :
Mouse IgG1, κ
Other Names :
Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, HER1
Size :
25 tests
Price (USD) :
117 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Immunogen :
Non-small cell lung cancer (NSCLC) cell line NCI-H322
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA