Alexa Fluor® 647 anti-human TCR Vα7.2 | BioLegend 351725 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 647 anti-human TCR Vα7.2

catalog :

351725

quantity :

25 tests

price :

159 USD

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

3C10

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1a	Salio M, Gasser O, González López C, Martens A, Veerapen N, Gileadi U, et al. Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells. J Immunol. 2017;199:2631-2638 pubmed publisher
flow cytometry; human; loading ...; fig 3b	Szabo P, Goswami A, Mazzuca D, Kim K, O Gorman D, Hess D, et al. Rapid and Rigorous IL-17A Production by a Distinct Subpopulation of Effector Memory T Lymphocytes Constitutes a Novel Mechanism of Toxic Shock Syndrome Immunopathology. J Immunol. 2017;198:2805-2818 pubmed publisher
flow cytometry; human; loading ...; tbl 1	Sumatoh H, Teng K, Cheng Y, Newell E. Optimization of mass cytometry sample cryopreservation after staining. Cytometry A. 2017;91:48-61 pubmed publisher
flow cytometry; human; 1:20	Held K, BeltrÃ¡n E, Moser M, Hohlfeld R, Dornmair K. T-cell receptor repertoire of human peripheral CD161hiTRAV1-2+ MAIT cells revealed by next generation sequencing and single cell analysis. Hum Immunol. 2015;76:607-14 pubmed publisher
flow cytometry; human; fig 1	Leeansyah E, SvÃ¤rd J, Dias J, Buggert M, NystrÃ¶m J, Quigley M, et al. Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. PLoS Pathog. 2015;11:e1005072 pubmed publisher
flow cytometry; human; fig 2	Salerno Goncalves R, Rezwan T, Sztein M. B cells modulate mucosal associated invariant T cell immune responses. Front Immunol. 2014;4:511 pubmed publisher
	Voskamp C, Koevoet W, Somoza R, Caplan A, Lefebvre V, van Osch G, et al. Enhanced Chondrogenic Capacity of Mesenchymal Stem Cells After TNFα Pre-treatment. Front Bioeng Biotechnol. 2020;8:658 pubmed publisher
	Xi H, Langerman J, Sabri S, Chien P, Young C, Younesi S, et al. A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell. 2020;27:158-176.e10 pubmed publisher
	Karlsson J, Nilsson L, Mitra S, Alsén S, Shelke G, Sah V, et al. Molecular profiling of driver events in metastatic uveal melanoma. Nat Commun. 2020;11:1894 pubmed publisher
	Srideshikan S, Brooks J, Zuro D, Kumar B, Sanchez J, Echavarria Parra L, et al. ImmunoPET, [64Cu]Cu-DOTA-Anti-CD33 PET-CT, Imaging of an AML Xenograft Model. Clin Cancer Res. 2019;25:7463-7474 pubmed publisher
	Hasselmann J, Coburn M, England W, Figueroa Velez D, Kiani Shabestari S, Tu C, et al. Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. Neuron. 2019;103:1016-1033.e10 pubmed publisher
	Wakao H, Yoshikiyo K, Koshimizu U, Furukawa T, Enomoto K, Matsunaga T, et al. Expansion of functional human mucosal-associated invariant T cells via reprogramming to pluripotency and redifferentiation. Cell Stem Cell. 2013;12:546-58 pubmed publisher

product information

Antigen :

TCR Valpha7.2

Apps. Abbrev. :

Flow Cytometry, SB

Cat # :

351725

Clone :

3C10

Item :

Alexa Fluor® 647 anti-human TCR Vα7.2

Isotype :

Mouse IgG1, κ

Other Names :

T cell antigen receptor Vα7.2

Size :

25 tests

Price (USD) :

159 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

A647

Immunogen :

Recombinant TCR

Application Notes :

Associated with an anti-CD161 or -IL18Ra staining, the 3C10 antibody allows unequivocal identification of MAIT cells. Importantly, the Va7.2 segment can also be used by conventional T cells. Therefore, the 3C10 also stains a subset of conventional CD4 and CD8 T cells. Additional reported applications (for the relevant formats) include: spatial biology (IBEX) 3,4 .

more info or order :

BioLegend product webpage