Brilliant Violet 421™ anti-human TCR Vα7.2 | BioLegend 351716 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 421™ anti-human TCR Vα7.2

catalog :

351716

quantity :

100 tests

price :

435 USD

clonality :

monoclonal

host :

mouse

conjugate :

BV421

clone name :

3C10

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 4

Reference
Nel I, Beaudoin L, Gouda Z, Rousseau C, Soulard P, Rouland M, et al. MAIT cell alterations in adults with recent-onset and long-term type 1 diabetes. Diabetologia. 2021;64:2306-2321 pubmed publisher
Wang J, Xu Y, Chen Z, Liang J, Lin Z, Liang H, et al. Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia. Cell. 2020;183:1867-1883.e26 pubmed publisher
Barbarin A, Cayssials E, Jacomet F, Núñez N, Basbous S, Lefèvre L, et al. Phenotype of NK-Like CD8(+) T Cells with Innate Features in Humans and Their Relevance in Cancer Diseases. Front Immunol. 2017;8:316 pubmed publisher
Rout N. Enhanced Th1/Th17 Functions of CD161+ CD8+ T Cells in Mucosal Tissues of Rhesus Macaques. PLoS ONE. 2016;11:e0157407 pubmed publisher

product information

Antigen :

TCR Valpha7.2

Apps. Abbrev. :

Cat # :

351716

Clone :

3C10

Item :

Brilliant Violet 421™ anti-human TCR Vα7.2

Isotype :

Mouse IgG1, κ

Other Names :

T cell antigen receptor Vα7.2

Size :

100 tests

Price (USD) :

435 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

BV421

Immunogen :

Recombinant TCR

Application Notes :

Associated with an anti-CD161 or -IL18Ra staining, the 3C10 antibody allows unequivocal identification of MAIT cells. Importantly, the Va7.2 segment can also be used by conventional T cells. Therefore, the 3C10 also stains a subset of conventional CD4 and CD8 T cells. Additional reported applications (for the relevant formats) include: spatial biology (IBEX)^3,4.;

more info or order :

BioLegend product webpage