FITC anti-human TCR Vα7.2 | BioLegend 351704 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

FITC anti-human TCR Vα7.2

catalog :

351704

quantity :

100 tests

price :

276 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

3C10

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1a	Lee C, Zhang H, Singh S, Koo L, Kabat J, Tsang H, et al. C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation. elife. 2018;7: pubmed publisher
	Leng T, Akther H, Hackstein C, Powell K, King T, Friedrich M, et al. TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions. Cell Rep. 2019;28:3077-3091.e5 pubmed publisher
	Ben Youssef G, Tourret M, Salou M, Ghazarian L, Houdouin V, Mondot S, et al. Ontogeny of human mucosal-associated invariant T cells and related T cell subsets. J Exp Med. 2018;215:459-479 pubmed publisher
	Jiang J, Chen X, An H, Yang B, Zhang F, Cheng X. Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling. Sci Rep. 2016;6:32320 pubmed publisher
	van Wilgenburg B, Scherwitzl I, Hutchinson E, Leng T, Kurioka A, Kulicke C, et al. MAIT cells are activated during human viral infections. Nat Commun. 2016;7:11653 pubmed publisher
	Leeansyah E, Loh L, Nixon D, Sandberg J. Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development. Nat Commun. 2014;5:3143 pubmed publisher
	Wakao H, Yoshikiyo K, Koshimizu U, Furukawa T, Enomoto K, Matsunaga T, et al. Expansion of functional human mucosal-associated invariant T cells via reprogramming to pluripotency and redifferentiation. Cell Stem Cell. 2013;12:546-58 pubmed publisher

product information

Antigen :

TCR Valpha7.2

Apps. Abbrev. :

Flow Cytometry

Cat # :

351704

Clone :

3C10

Item :

FITC anti-human TCR Vα7.2

Isotype :

Mouse IgG1, κ

Other Names :

T cell antigen receptor Vα7.2

Size :

100 tests

Price (USD) :

276 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

FITC

Immunogen :

Recombinant TCR

Application Notes :

Associated with an anti-CD161 or -IL18Ra staining, the 3C10 antibody allows unequivocal identification of MAIT cells. Importantly, the Va7.2 segment can also be used by conventional T cells. Therefore, the 3C10 also stains a subset of conventional CD4 and CD8 T cells. Additional reported applications (for the relevant formats) include: spatial biology (IBEX) 3,4 .

more info or order :

BioLegend product webpage