product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human CD127 (IL-7Rα)
catalog :
351310
quantity :
100 tests
price :
402 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
A019D5
reactivity :
human, mouse, rhesus macaque
application :
flow cytometry
more info or order :
citations: 36
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:100; loading ...; fig s7a
Ercolano G, Gomez Cadena A, Dumauthioz N, Vanoni G, Kreutzfeldt M, Wyss T, et al. PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions. Nat Commun. 2021;12:2538 pubmed publisher
  • flow cytometry; human; loading ...; fig s1-1
Kasatskaya S, Ladell K, Egorov E, Miners K, Davydov A, Metsger M, et al. Functionally specialized human CD4+ T-cell subsets express physicochemically distinct TCRs. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...
Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
  • flow cytometry; human; loading ...; fig s7b
Zou F, Lu L, Liu J, Xia B, Zhang W, Hu Q, et al. Engineered triple inhibitory receptor resistance improves anti-tumor CAR-T cell performance via CD56. Nat Commun. 2019;10:4109 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
de Jonge K, Ebering A, Nassiri S, Maby El Hajjami H, Ouertatani Sakouhi H, Baumgaertner P, et al. Circulating CD56bright NK cells inversely correlate with survival of melanoma patients. Sci Rep. 2019;9:4487 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Inoue Y, Endo S, Matsuno N, Kikukawa Y, Shichijo T, Koga K, et al. Safety of mogamulizumab for relapsed ATL after allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2018;: pubmed publisher
  • flow cytometry; human; loading ...; tbl s9
Mordmuller B, Surat G, Lagler H, Chakravarty S, Ishizuka A, Lalremruata A, et al. Sterile protection against human malaria by chemoattenuated PfSPZ vaccine. Nature. 2017;542:445-449 pubmed publisher
  • flow cytometry; human; loading ...; fig s2
Zwang N, Zhang R, Germana S, Fan M, Hastings W, Cao A, et al. Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways. Am J Transplant. 2016;16:2624-38 pubmed publisher
  • flow cytometry; human
Dyring Andersen B, Bonefeld C, Bzorek M, Løvendorf M, Lauritsen J, Skov L, et al. The Vitamin D Analogue Calcipotriol Reduces the Frequency of CD8+ IL-17+ T Cells in Psoriasis Lesions. Scand J Immunol. 2015;82:84-91 pubmed publisher
Imai Y, Kusakabe M, Nagai M, Yasuda K, Yamanishi K. Dupilumab Effects on Innate Lymphoid Cell and Helper T Cell Populations in Patients with Atopic Dermatitis. JID Innov. 2021;1:100003 pubmed publisher
O Connor M, Muir R, Chakhtoura M, Fang M, Moysi E, Moir S, et al. A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cells. Commun Biol. 2021;4:563 pubmed publisher
Crump N, Hadjinicolaou A, Xia M, Walsby Tickle J, Gileadi U, Chen J, et al. Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation. Cell Rep. 2021;35:109101 pubmed publisher
Gonzalez Figueroa P, Roco J, Papa I, Núñez Villacís L, Stanley M, Linterman M, et al. Follicular regulatory T cells produce neuritin to regulate B cells. Cell. 2021;184:1775-1789.e19 pubmed publisher
Vanoni G, Ercolano G, Candiani S, Rutigliani M, Lanata M, Derre L, et al. Human primed ILCPs support endothelial activation through NF-κB signaling. elife. 2021;10: pubmed publisher
Kim D, Kim H, Cho S, Yoo S, Kim W, Yeon H, et al. Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells. elife. 2021;10: pubmed publisher
Lev A, Simon A, Barel O, Eyal E, Glick Saar E, Nayshool O, et al. Reduced Function and Diversity of T Cell Repertoire and Distinct Clinical Course in Patients With IL7RA Mutation. Front Immunol. 2019;10:1672 pubmed publisher
Cella M, Gamini R, Sécca C, Collins P, Zhao S, Peng V, et al. Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues. Nat Immunol. 2019;: pubmed publisher
Tardif V, Muir R, Cubas R, Chakhtoura M, Wilkinson P, Metcalf T, et al. Adenosine deaminase-1 delineates human follicular helper T cell function and is altered with HIV. Nat Commun. 2019;10:823 pubmed publisher
Miragaia R, Gomes T, Chomka A, Jardine L, Riedel A, Hegazy A, et al. Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation. Immunity. 2019;50:493-504.e7 pubmed publisher
Collins P, Cella M, Porter S, Li S, Gurewitz G, Hong H, et al. Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells. Cell. 2019;176:348-360.e12 pubmed publisher
Kong X, Martinez Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick E, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nat Immunol. 2018;19:973-985 pubmed publisher
Morimoto Y, Hirahara K, Kiuchi M, Wada T, Ichikawa T, Kanno T, et al. Amphiregulin-Producing Pathogenic Memory T Helper 2 Cells Instruct Eosinophils to Secrete Osteopontin and Facilitate Airway Fibrosis. Immunity. 2018;49:134-150.e6 pubmed publisher
Cuadrado E, van den Biggelaar M, de Kivit S, Chen Y, Slot M, Doubal I, et al. Proteomic Analyses of Human Regulatory T Cells Reveal Adaptations in Signaling Pathways that Protect Cellular Identity. Immunity. 2018;48:1046-1059.e6 pubmed publisher
Trabanelli S, Chevalier M, Martinez Usatorre A, Gomez Cadena A, Salomé B, Lecciso M, et al. Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis. Nat Commun. 2017;8:593 pubmed publisher
Burke M, Sambira Nahum L, Isbel N, Carroll R, Soyer H, Francis R, et al. Sirolimus Increases T-Cell Abundance in the Sun Exposed Skin of Kidney Transplant Recipients. Transplant Direct. 2017;3:e171 pubmed publisher
Wright A, Weston C, Rana B, Brightling C, Cousins D. Human group 2 innate lymphoid cells do not express the IL-5 receptor. J Allergy Clin Immunol. 2017;140:1430-1433.e4 pubmed publisher
Judge C, Kostadinova L, Sherman K, Butt A, Falck Ytter Y, Funderburg N, et al. CD56bright NK IL-7Rα expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections. J Leukoc Biol. 2017;102:171-184 pubmed publisher
Mackroth M, Abel A, Steeg C, Schulze zur Wiesch J, Jacobs T. Acute Malaria Induces PD1+CTLA4+ Effector T Cells with Cell-Extrinsic Suppressor Function. PLoS Pathog. 2016;12:e1005909 pubmed publisher
Kimura K, Nakamura M, Sato W, Okamoto T, Araki M, Lin Y, et al. Disrupted balance of T cells under natalizumab treatment in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. 2016;3:e210 pubmed publisher
Eller M, Goonetilleke N, Tassaneetrithep B, Eller L, Costanzo M, Johnson S, et al. Expansion of Inefficient HIV-Specific CD8 T Cells during Acute Infection. J Virol. 2016;90:4005-4016 pubmed publisher
De Grove K, Provoost S, Verhamme F, Bracke K, Joos G, Maes T, et al. Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung. PLoS ONE. 2016;11:e0145961 pubmed publisher
Li Causi E, Parikh S, Chudley L, Layfield D, Ottensmeier C, Stevenson F, et al. Vaccination Expands Antigen-Specific CD4+ Memory T Cells and Mobilizes Bystander Central Memory T Cells. PLoS ONE. 2015;10:e0136717 pubmed publisher
Fuhrman C, Yeh W, Seay H, Saikumar Lakshmi P, Chopra G, Zhang L, et al. Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226. J Immunol. 2015;195:145-55 pubmed publisher
Willmann K, Klaver S, DoÄŸu F, Santos Valente E, Garncarz W, Bilic I, et al. Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity. Nat Commun. 2014;5:5360 pubmed publisher
Xu Y, Fernandez C, Alcantara S, Bailey M, De Rose R, Kelleher A, et al. Serial study of lymph node cell subsets using fine needle aspiration in pigtail macaques. J Immunol Methods. 2013;394:73-83 pubmed publisher
Xu Y, Weatherall C, Bailey M, Alcantara S, De Rose R, Estaquier J, et al. Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J Virol. 2013;87:3760-73 pubmed publisher
product information
Antigen :
CD127
Apps. Abbrev. :
Flow Cytometry
Cat # :
351310
Clone :
A019D5
Item :
Brilliant Violet 421™ anti-human CD127 (IL-7Rα)
Isotype :
Mouse IgG1, κ
Other Names :
IL-7 receptor α chain, IL-7Rα
Size :
100 tests
Price (USD) :
402 USD
Reactivity :
Human, African Green, Baboon, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Immunogen :
Recombinant human CD127
Application Notes :
Additional reported (for the relevant formats) application: proteogenomics 1 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA