product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD243 (MDR-1)
catalog :
348607
quantity :
25 tests
price :
149 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
UIC2
reactivity :
human
application :
flow cytometry
more info or order :
citations: 5
Reference
Payton M, Belmontes B, Hanestad K, Moriguchi J, Chen K, McCarter J, et al. Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers. Nat Cancer. 2024;5:66-84 pubmed publisher
Foley S, Tuohy C, Dunford M, Grey M, De Luca H, Cawley C, et al. Gut microbiota regulation of P-glycoprotein in the intestinal epithelium in maintenance of homeostasis. Microbiome. 2021;9:183 pubmed publisher
Haran J, Bhattarai S, Foley S, Dutta P, Ward D, Bucci V, et al. Alzheimer's Disease Microbiome Is Associated with Dysregulation of the Anti-Inflammatory P-Glycoprotein Pathway. MBio. 2019;10: pubmed publisher
Chen F, Lv X, Zhao Q, Xu Y, Song S, Yu W, et al. Inhibitor of DNA binding 3 reverses cisplatin resistance in human lung adenocarcinoma cells by regulating the PI3K/Akt pathway. Oncol Lett. 2018;16:1634-1640 pubmed publisher
Sauveur J, Matera E, Chettab K, Valet P, Guitton J, Savina A, et al. Esophageal cancer cells resistant to T-DM1 display alterations in cell adhesion and the prostaglandin pathway. Oncotarget. 2018;9:21141-21155 pubmed publisher
product information
Antigen :
CD243
Apps. Abbrev. :
FC
Cat # :
348607
Clone :
UIC2
Item :
APC anti-human CD243 (MDR-1)
Isotype :
Mouse IgG2a, κ
Other Names :
Multidrug resistance protein 1, ATP-binding cassette sub-family B member 1, P-glycoprotein 1
Size :
25 tests
Price (USD) :
149 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
NIH 3T3 cells transfected with human MDR-1 cDNA
Application Notes :
Additional reported applications (for the relevant formats) include: blocking the efflux of fluorescent dyes^1,2, immunoprecipitation^1, and immunohistochemical staining of tissue sections of squamous cell carcinoma^3.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA