Brilliant Violet 421™ anti-human CD115 (CSF-1R) | BioLegend 347322 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 421™ anti-human CD115 (CSF-1R)

catalog :

347322

quantity :

100 tests

price :

381 USD

clonality :

monoclonal

host :

rat

conjugate :

BV421

clone name :

9-4D2-1E4

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 2

Reference
Thompson E, Carlino M, Scanlon V, Grimes H, Krause D. Assay optimization for the objective quantification of human multilineage colony-forming units. Exp Hematol. 2023;124:36-44.e3 pubmed publisher
Mehta A, Cheney E, Hartl C, Pantelidou C, Oliwa M, Castrillon J, et al. Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer. Nat Cancer. 2021;2:66-82 pubmed publisher

product information

Antigen :

CD115

Apps. Abbrev. :

Cat # :

347322

Clone :

9-4D2-1E4

Item :

Brilliant Violet 421™ anti-human CD115 (CSF-1R)

Isotype :

Rat IgG1, κ

Other Names :

M-CSFR,CSF-1R, FMS, CSF-1 Receptor

Size :

100 tests

Price (USD) :

381 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BV421

Immunogen :

C-fms transduced Kirsten strain murine sarcoma virus transformed NRK cells.

Application Notes :

It has been reported that CD115 can be rapidly internalized, especially when samples are exposed to room temperature. Approximate 33% decrease in CD115 expression has been observed between 0 and 4 hours after sample collection, while overnight incubation of the cells results in complete CD115 downregulation. Pre-treatment with EDTA and low temperatures (2 to 8°C) helps in maintaining surface expression of CD115^1.;

more info or order :

BioLegend product webpage