Alexa Fluor® 488 anti-human CD115 (CSF-1R) | BioLegend 347311 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 488 anti-human CD115 (CSF-1R)

catalog :

347311

quantity :

25 tests

price :

153 USD

clonality :

monoclonal

host :

rat

conjugate :

AF488

clone name :

9-4D2-1E4

reactivity :

human, mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 2a	Zhang Z, Le K, La Placa D, Armstrong B, Miller M, Shively J. CXCR2 specific endocytosis of immunomodulatory peptide LL-37 in human monocytes and formation of LL-37 positive large vesicles in differentiated monoosteophils. Bone Rep. 2020;12:100237 pubmed publisher
flow cytometry; mouse; loading ...; fig s1b	Perry C, Muñoz Rojas A, Meeth K, Kellman L, Amezquita R, Thakral D, et al. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. J Exp Med. 2018;215:877-893 pubmed publisher
flow cytometry; human; loading ...; fig 1e	Bujko A, Atlasy N, Landsverk O, Richter L, Yaqub S, Horneland R, et al. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J Exp Med. 2018;215:441-458 pubmed publisher
flow cytometry; human; fig 4	Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
	Shen Y, Hua L, Yeh C, Shen L, Ying M, Zhang Z, et al. Ultrasound with microbubbles improves memory, ameliorates pathology and modulates hippocampal proteomic changes in a triple transgenic mouse model of Alzheimer's disease. Theranostics. 2020;10:11794-11819 pubmed publisher
	Rodriguez B, Vega Soto E, Kennedy C, Nguyen M, Cederna P, Larkin L. A tissue engineering approach for repairing craniofacial volumetric muscle loss in a sheep following a 2, 4, and 6-month recovery. PLoS ONE. 2020;15:e0239152 pubmed publisher
	Shao W, Yang J, He M, Yu X, Lee C, Yang Z, et al. Centrosome anchoring regulates progenitor properties and cortical formation. Nature. 2020;580:106-112 pubmed publisher
	Qian X, Su Y, Adam C, Deutschmann A, Pather S, Goldberg E, et al. Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation. Cell Stem Cell. 2020;26:766-781.e9 pubmed publisher
	Fifield K, Vanderluit J. Rapid degeneration of neurons in the penumbra region following a small, focal ischemic stroke. Eur J Neurosci. 2020;52:3196-3214 pubmed publisher
	Kennedy J, Steain M, Slobedman B, Abendroth A. Infection and Functional Modulation of Human Monocytes and Macrophages by Varicella-Zoster Virus. J Virol. 2019;93: pubmed publisher

product information

Antigen :

CD115

Apps. Abbrev. :

Cat # :

347311

Clone :

9-4D2-1E4

Item :

Alexa Fluor® 488 anti-human CD115 (CSF-1R)

Isotype :

Rat IgG1, κ

Other Names :

M-CSFR,CSF-1R, FMS, CSF-1 Receptor

Size :

25 tests

Price (USD) :

153 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

A488

Immunogen :

C-fms transduced Kirsten strain murine sarcoma virus transformed NRK cells.

Application Notes :

It has been reported that CD115 can be rapidly internalized, especially when samples are exposed to room temperature. Approximate 33% decrease in CD115 expression has been observed between 0 and 4 hours after sample collection, while overnight incubation of the cells results in complete CD115 downregulation. Pre-treatment with EDTA and low temperatures (2 to 8°C) helps in maintaining surface expression of CD115^1.;

more info or order :

BioLegend product webpage