APC anti-human CD115 (CSF-1R) | BioLegend 347305 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human CD115 (CSF-1R)

catalog :

347305

quantity :

25 tests

price :

154 USD

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

9-4D2-1E4

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 4	Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
	Yamaguchi Y, Gibson J, Ou K, Lopez L, Ng R, Leggett N, et al. PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophages. J Immunother Cancer. 2022;10: pubmed publisher
	Patel C, Shi L, Whitesides J, Foster B, Fajardo R, Quillen E, et al. A New Method of Bone Stromal Cell Characterization by Flow Cytometry. Curr Protoc. 2022;2:e400 pubmed publisher
	Magg T, Okano T, Koenig L, Boehmer D, Schwartz S, Inoue K, et al. Heterozygous OAS1 gain-of-function variants cause an autoinflammatory immunodeficiency. Sci Immunol. 2021;6: pubmed publisher
	McDaniel M, Kottyan L, Singh H, Pasare C. Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming. Cell Rep. 2020;31:107604 pubmed publisher
	Moon H, Kim S, Jeong J, Han S, Jarjour N, Lee H, et al. Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization. Immunity. 2018;49:275-287.e5 pubmed publisher
	Alhaj Hussen K, Vu Manh T, Guimiot F, Nelson E, Chabaane E, Delord M, et al. Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis. Immunity. 2017;47:680-696.e8 pubmed publisher
	Lavin Y, Kobayashi S, Leader A, Amir E, Elefant N, Bigenwald C, et al. Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses. Cell. 2017;169:750-765.e17 pubmed publisher
	Breton G, Lee J, Zhou Y, Schreiber J, Keler T, PUHR S, et al. Circulating precursors of human CD1c+ and CD141+ dendritic cells. J Exp Med. 2015;212:401-13 pubmed publisher

product information

Antigen :

CD115

Apps. Abbrev. :

Cat # :

347305

Clone :

9-4D2-1E4

Item :

APC anti-human CD115 (CSF-1R)

Isotype :

Rat IgG1, κ

Other Names :

M-CSFR,CSF-1R, FMS, CSF-1 Receptor

Size :

25 tests

Price (USD) :

154 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC

Immunogen :

C-fms transduced Kirsten strain murine sarcoma virus transformed NRK cells.

Application Notes :

It has been reported that CD115 can be rapidly internalized, especially when samples are exposed to room temperature. Approximate 33% decrease in CD115 expression has been observed between 0 and 4 hours after sample collection, while overnight incubation of the cells results in complete CD115 downregulation. Pre-treatment with EDTA and low temperatures (2 to 8°C) helps in maintaining surface expression of CD115^1.;

more info or order :

BioLegend product webpage