PE anti-human CD115 (CSF-1R) | BioLegend 347304 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human CD115 (CSF-1R)

catalog :

347304

quantity :

100 tests

price :

288 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

9-4D2-1E4

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1e	Bujko A, Atlasy N, Landsverk O, Richter L, Yaqub S, Horneland R, et al. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J Exp Med. 2018;215:441-458 pubmed publisher
flow cytometry; human	Jitschin R, Braun M, Büttner M, Dettmer Wilde K, Bricks J, Berger J, et al. CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs. Blood. 2014;124:750-60 pubmed publisher
	Leylek R, Alcántara Hernández M, Granja J, Chavez M, Perez K, Diaz O, et al. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Rep. 2020;32:108180 pubmed publisher
	Cytlak U, Resteu A, Pagan S, Green K, Milne P, Maisuria S, et al. Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans. Immunity. 2020;53:353-370.e8 pubmed publisher
	Guo Y, Hong W, Zhang P, Han D, Fang Y, Tu J, et al. Abnormal polarization of macrophage-like cells in the peripheral blood of patients with glioma. Oncol Lett. 2020;20:947-954 pubmed publisher
	Wu L, Liu H, Guo H, Wu Q, Yu S, Qin Y, et al. Circulating and tumor-infiltrating myeloid-derived suppressor cells in cervical carcinoma patients. Oncol Lett. 2018;15:9507-9515 pubmed publisher
	Kumar V, Donthireddy L, Marvel D, Condamine T, Wang F, Lavilla Alonso S, et al. Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors. Cancer Cell. 2017;32:654-668.e5 pubmed publisher
	Singh N, Herbert B, Sooranna G, Orsi N, Edey L, Dasgupta T, et al. Is myometrial inflammation a cause or a consequence of term human labour?. J Endocrinol. 2017;235:69-83 pubmed publisher
	Schrøder M, Melum G, Landsverk O, Bujko A, Yaqub S, Gran E, et al. CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits. PLoS ONE. 2016;11:e0157387 pubmed publisher

product information

Antigen :

CD115

Apps. Abbrev. :

Cat # :

347304

Clone :

9-4D2-1E4

Item :

PE anti-human CD115 (CSF-1R)

Isotype :

Rat IgG1, κ

Other Names :

M-CSFR,CSF-1R, FMS, CSF-1 Receptor

Size :

100 tests

Price (USD) :

288 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

C-fms transduced Kirsten strain murine sarcoma virus transformed NRK cells.

Application Notes :

It has been reported that CD115 can be rapidly internalized, especially when samples are exposed to room temperature. Approximate 33% decrease in CD115 expression has been observed between 0 and 4 hours after sample collection, while overnight incubation of the cells results in complete CD115 downregulation. Pre-treatment with EDTA and low temperatures (2 to 8°C) helps in maintaining surface expression of CD115^1.;

more info or order :

BioLegend product webpage