product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human Siglec-8
catalog :
347104
quantity :
100 tests
price :
360 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
7C9
reactivity :
human
application :
flow cytometry
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 2 ug/ml; loading ...; fig 1b
Duan S, Koziol White C, Jester W, Nycholat C, Macauley M, Panettieri R, et al. CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen. J Clin Invest. 2019;129:1387-1401 pubmed publisher
Bohrer A, Castro E, Tocheny C, Assmann M, Schwarz B, Bohrnsen E, et al. Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection. Cell Rep. 2022;40:111144 pubmed publisher
Cossarizza A, Chang H, Radbruch A, Abrignani S, Addo R, Akdis M, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition). Eur J Immunol. 2021;51:2708-3145 pubmed publisher
Duan S, Arlian B, Nycholat C, Wei Y, Tateno H, Smith S, et al. Nanoparticles Displaying Allergen and Siglec-8 Ligands Suppress IgE-FcεRI-Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Challenge. J Immunol. 2021;206:2290-2300 pubmed publisher
Youngblood B, Leung J, Falahati R, Williams J, Schanin J, Brock E, et al. Discovery, Function, and Therapeutic Targeting of Siglec-8. Cells. 2020;10: pubmed publisher
Fan Z, Mikulski Z, McArdle S, Sundd P, Ley K. Super-STORM: Molecular Modeling to Achieve Single-molecule Localization with STORM Microscopy. STAR Protoc. 2020;1:100012 pubmed publisher
Hernandez J, Tew B, Li T, Gooden G, Ghannam H, Masuda M, et al. A FACS-based approach to obtain viable eosinophils from human adipose tissue. Sci Rep. 2020;10:13210 pubmed publisher
Serra E, Schwerd T, Moutsianas L, Cavounidis A, Fachal L, Pandey S, et al. Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease. Nat Commun. 2020;11:995 pubmed publisher
Lippeveld M, Knill C, Ladlow E, Fuller A, Michaelis L, Saeys Y, et al. Classification of Human White Blood Cells Using Machine Learning for Stain-Free Imaging Flow Cytometry. Cytometry A. 2020;97:308-319 pubmed publisher
Legrand F, Cao Y, Wechsler J, Zhu X, Zimmermann N, Rampertaap S, et al. Sialic acid-binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies. J Allergy Clin Immunol. 2019;143:2227-2237.e10 pubmed publisher
Gadkari M, Makiya M, Legrand F, Stokes K, Brown T, Howe K, et al. Transcript- and protein-level analyses of the response of human eosinophils to glucocorticoids. Sci Data. 2018;5:180275 pubmed publisher
Motwani M, Colas R, George M, Flint J, Dalli J, Richard Loendt A, et al. Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation. JCI Insight. 2018;3: pubmed publisher
Siddiqui S, Springer S, Verhagen A, Sundaramurthy V, Alisson Silva F, Jiang W, et al. The Alzheimer's disease-protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool. J Biol Chem. 2017;292:15312-15320 pubmed publisher
Lin J, Sodenkamp J, Cunningham D, Deroost K, Tshitenge T, McLaughlin S, et al. Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria. Sci Rep. 2017;7:41722 pubmed publisher
Wright A, Mahaut Smith M, Symon F, Sylvius N, Ran S, Bafadhel M, et al. Impaired P2X1 Receptor-Mediated Adhesion in Eosinophils from Asthmatic Patients. J Immunol. 2016;196:4877-84 pubmed publisher
Bal S, Bernink J, Nagasawa M, Groot J, Shikhagaie M, Golebski K, et al. IL-1?, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs. Nat Immunol. 2016;17:636-45 pubmed publisher
Jenner W, Motwani M, Veighey K, Newson J, Audzevich T, Nicolaou A, et al. Characterisation of leukocytes in a human skin blister model of acute inflammation and resolution. PLoS ONE. 2014;9:e89375 pubmed publisher
Kano G, Almanan M, Bochner B, Zimmermann N. Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activation. J Allergy Clin Immunol. 2013;132:437-45 pubmed publisher
Wong T, Jelinek D. Purification of functional eosinophils from human bone marrow. J Immunol Methods. 2013;387:130-9 pubmed publisher
product information
Antigen :
Siglec-8
Apps. Abbrev. :
FC
Cat # :
347104
Clone :
7C9
Item :
PE anti-human Siglec-8
Isotype :
Mouse IgG1, κ
Other Names :
Sialic acid-binding Ig-like lectin 8 (Siglec-8), Siglec8L, Sialoadhesin family member 2 (SAF2)
Size :
100 tests
Price (USD) :
360 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Immunogen :
Recombinant Siglec-8 fused to human IgG Fc
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA