APC anti-human CD158d (KIR2DL4) | BioLegend 347008 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human CD158d (KIR2DL4)

catalog :

347008

quantity :

100 tests

price :

362 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

mAb 33 (33)

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 2

Reference
Fu B, Zhou Y, Ni X, Tong X, Xu X, Dong Z, et al. Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors. Immunity. 2017;47:1100-1113.e6 pubmed publisher
Brusilovsky M, Cordoba M, Rosental B, Hershkovitz O, Andrake M, Pecherskaya A, et al. Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses. J Immunol. 2013;191:5256-67 pubmed publisher

product information

Antigen :

CD158d

Apps. Abbrev. :

Cat # :

347008

Clone :

mAb 33 (33)

Item :

APC anti-human CD158d (KIR2DL4)

Isotype :

Mouse IgG1, κ

Other Names :

KIR2DL4, 2DL4, p49, KIR103

Size :

100 tests

Price (USD) :

362 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC

Immunogen :

NK3.3 cells and KIR2DL4-Ig fusion protein

Application Notes :

KIR2DL4 expression in NK cells is highly localized to the endosomes^3. mAb 33 can be internalized by NK cells by endocytosis at 37°C^3, and induces NK cell cytotoxicity^1,2. Based on in-house observations, we suggest incubating for 45 - 60 minutes at room temperature with clone mAb 33 to observe better CD158d staining.This clone has been tested in-house and determined to not be suitable for applications in immunohistochemistry of paraffin-embedded tissue sections (IHC-P).;

more info or order :

BioLegend product webpage