PE anti-human CD158d (KIR2DL4) | BioLegend 347005 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human CD158d (KIR2DL4)

catalog :

347005

quantity :

25 tests

price :

153 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

mAb 33 (33)

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 6

Reference
Chen M, Li Y, Wu Y, Xie S, Ma J, Yue J, et al. Anti-Tumor Activity of Expanded PBMC-Derived NK Cells by Feeder-Free Protocol in Ovarian Cancer. Cancers (Basel). 2021;13: pubmed publisher
Samarani S, Sagala P, Jantchou P, Grimard G, Faure C, Deslandres C, et al. Phenotypic and Functional Changes in Peripheral Blood Natural Killer Cells in Crohn Disease Patients. Mediators Inflamm. 2020;2020:6401969 pubmed publisher
Albayati Z, Alyami A, Alomar S, Middleton D, Bonnett L, Aleem S, et al. The Influence of Cytomegalovirus on Expression of HLA-G and its Ligand KIR2DL4 by Human Peripheral Blood Leucocyte Subsets. Scand J Immunol. 2017;86:396-407 pubmed publisher
Xu X, Zhao M, Liu X, Jiang Y, Zhang H, Zhai X, et al. Toxoplasma gondii infection regulates the balance of activating and inhibitory receptors on decidual natural killer cells. PLoS ONE. 2013;8:e55432 pubmed publisher
Xu X, Fu Q, Zhang Q, Zhao M, Gao Z, Liu X, et al. Changes of human decidual natural killer cells cocultured with YFP-Toxoplasma gondii: implications for abnormal pregnancy. Fertil Steril. 2013;99:427-32 pubmed publisher
Presnell S, Zhang L, Chlebowy C, Al Attar A, Lutz C. Differential transcription factor use by the KIR2DL4 promoter under constitutive and IL-2/15-treated conditions. J Immunol. 2012;188:4394-404 pubmed publisher

product information

Antigen :

CD158d

Apps. Abbrev. :

Cat # :

347005

Clone :

mAb 33 (33)

Item :

PE anti-human CD158d (KIR2DL4)

Isotype :

Mouse IgG1, κ

Other Names :

KIR2DL4, 2DL4, p49, KIR103

Size :

25 tests

Price (USD) :

153 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Immunogen :

NK3.3 cells and KIR2DL4-Ig fusion protein

Application Notes :

KIR2DL4 expression in NK cells is highly localized to the endosomes^3. mAb 33 can be internalized by NK cells by endocytosis at 37°C^3, and induces NK cell cytotoxicity^1,2. Based on in-house observations, we suggest incubating for 45 - 60 minutes at room temperature with clone mAb 33 to observe better CD158d staining.This clone has been tested in-house and determined to not be suitable for applications in immunohistochemistry of paraffin-embedded tissue sections (IHC-P).;

more info or order :

BioLegend product webpage