Purified anti-human CD273 (B7-DC, PD-L2) | BioLegend 345502 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human CD273 (B7-DC, PD-L2)

catalog :

345502

quantity :

100 μg

price :

112 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MIH18

reactivity :

human

application :

neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

BioLegend product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1c	Richardson J, Armbruster N, Günter M, Henes J, Autenrieth S. Staphylococcus aureus PSM Peptides Modulate Human Monocyte-Derived Dendritic Cells to Prime Regulatory T Cells. Front Immunol. 2018;9:2603 pubmed publisher
flow cytometry; human; tbl 3	Fromm J, Thomas A, Wood B. Characterization and Purification of Neoplastic Cells of Nodular Lymphocyte Predominant Hodgkin Lymphoma from Lymph Nodes by Flow Cytometry and Flow Cytometric Cell Sorting. Am J Pathol. 2017;187:304-317 pubmed publisher
	Nishi W, Wakamatsu E, Machiyama H, Matsushima R, Saito K, Yoshida Y, et al. Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters. Nat Commun. 2023;14:3157 pubmed publisher
	Sasaya T, Kubo T, Murata K, Mizue Y, Sasaki K, Yanagawa J, et al. Cisplatin-induced HSF1-HSP90 axis enhances the expression of functional PD-L1 in oral squamous cell carcinoma. Cancer Med. 2022;: pubmed publisher
	Baram T, Oren N, Erlichman N, Meshel T, Ben Baruch A. Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFα Receptors in Human Triple-Negative Breast Cancer. Cancers (Basel). 2022;14: pubmed publisher
	Zhu Y, Smith D, Zhou Y, Li Y, Yu J, Lee D, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019;25:542-557.e9 pubmed publisher
	Celis Gutierrez J, Blattmann P, Zhai Y, Jarmuzynski N, Ruminski K, Gregoire C, et al. Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy. Cell Rep. 2019;27:3315-3330.e7 pubmed publisher
	Chevrier S, Crowell H, Zanotelli V, Engler S, Robinson M, Bodenmiller B. Compensation of Signal Spillover in Suspension and Imaging Mass Cytometry. Cell Syst. 2018;6:612-620.e5 pubmed publisher
	Liu R, Merola J, Manes T, Qin L, Tietjen G, Lopez Giraldez F, et al. Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1. JCI Insight. 2018;3: pubmed publisher
	Kim M, Kim C, Kim S, Shin S, Choe E, Park S, et al. YAP-Induced PD-L1 Expression Drives Immune Evasion in BRAFi-Resistant Melanoma. Cancer Immunol Res. 2018;: pubmed publisher
	Chevrier S, Levine J, Zanotelli V, Silina K, Schulz D, Bacac M, et al. An Immune Atlas of Clear Cell Renal Cell Carcinoma. Cell. 2017;169:736-749.e18 pubmed publisher
	Taube J, Klein A, Brahmer J, Xu H, Pan X, Kim J, et al. Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin Cancer Res. 2014;20:5064-74 pubmed publisher
	Muthumani K, Shedlock D, Choo D, Fagone P, Kawalekar O, Goodman J, et al. HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells. J Immunol. 2011;187:2932-43 pubmed publisher

product information

Antigen :

CD273

Apps. Abbrev. :

FC, IHC-F, IHC-P, Block

Cat # :

345502

Clone :

MIH18

Item :

Purified anti-human CD273 (B7-DC, PD-L2)

Isotype :

Mouse IgG1, κ

Other Names :

B7-DC, PD-L2, PDL2, B7DC

Size :

100 μg

Price (USD) :

112 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

Human B7-DC transfected cells

Application Notes :

Additional reported applications (for the relevant formats) include: blocking^4,5, and immunohistochemistry in frozen sections^2 and paraffin-embedded formalin-fixed sections^6. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 345504).;

more info or order :

BioLegend product webpage