product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD366 (Tim-3)
catalog :
345011
quantity :
25 tests
price :
161 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
F38-2E2
reactivity :
human, mouse
application :
flow cytometry, other
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • other; mouse
Tseng H, Xiong W, Badeti S, Yang Y, Ma M, Liu T, et al. Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. Nat Commun. 2020;11:4810 pubmed publisher
  • flow cytometry; human; loading ...; fig 2b,2c
Huang R, Francois A, McGray A, Miliotto A, Odunsi K. Compensatory upregulation of PD-1, LAG-3, and CTLA-4 limits the efficacy of single-agent checkpoint blockade in metastatic ovarian cancer. Oncoimmunology. 2017;6:e1249561 pubmed publisher
Halim L, Das K, Larcombe Young D, Ajina A, Candelli A, Benjamin R, et al. Engineering of an Avidity-Optimized CD19-Specific Parallel Chimeric Antigen Receptor That Delivers Dual CD28 and 4-1BB Co-Stimulation. Front Immunol. 2022;13:836549 pubmed publisher
Li N, Tang N, Cheng C, Hu T, Wei X, Han W, et al. Improving the anti-solid tumor efficacy of CAR-T cells by inhibiting adenosine signaling pathway. Oncoimmunology. 2020;9:1824643 pubmed publisher
Zhang D, Jiang F, Zaynagetdinov R, Huang H, Sood V, Wang H, et al. Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody. Oncoimmunology. 2020;9:1744921 pubmed publisher
McGowan J, Peter C, Chattopadhyay S, Chakravarti R. 14-3-3ζ-A Novel Immunogen Promotes Inflammatory Cytokine Production. Front Immunol. 2019;10:1553 pubmed publisher
Wei J, Luo C, Wang Y, Guo Y, Dai H, Tong C, et al. PD-1 silencing impairs the anti-tumor function of chimeric antigen receptor modified T cells by inhibiting proliferation activity. J Immunother Cancer. 2019;7:209 pubmed publisher
Iwahori K, Shintani Y, Funaki S, Yamamoto Y, Matsumoto M, Yoshida T, et al. Peripheral T cell cytotoxicity predicts T cell function in the tumor microenvironment. Sci Rep. 2019;9:2636 pubmed publisher
Picard E, Godet Y, Laheurte C, Dosset M, Galaine J, Beziaud L, et al. Circulating NKp46+ Natural Killer cells have a potential regulatory property and predict distinct survival in Non-Small Cell Lung Cancer. Oncoimmunology. 2019;8:e1527498 pubmed publisher
Saraiva D, Jacinto A, Borralho P, Braga S, Cabral M. HLA-DR in Cytotoxic T Lymphocytes Predicts Breast Cancer Patients' Response to Neoadjuvant Chemotherapy. Front Immunol. 2018;9:2605 pubmed publisher
Zhou Y, Du J, Hou H, Lu Y, Yu J, Mao L, et al. Application of ImmunoScore Model for the Differentiation between Active Tuberculosis and Latent Tuberculosis Infection as Well as Monitoring Anti-tuberculosis Therapy. Front Cell Infect Microbiol. 2017;7:457 pubmed publisher
product information
Antigen :
CD366
Apps. Abbrev. :
Flow Cytometry
Cat # :
345011
Clone :
F38-2E2
Item :
APC anti-human CD366 (Tim-3)
Isotype :
Mouse IgG1, κ
Other Names :
T cell immunoglobulin and mucin domain containing protein 3, hepatitis virus cellular receptor 2, CD366
Size :
25 tests
Price (USD) :
161 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
Human Tim-3 fusion protein
Application Notes :
Additional reported applications (for relevant formats of this clone) include: costimulation 1 (clone 2E2 has been shown to enhance T-cell receptor mediated activation and cytokine secretion) and blocking 2,3 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA