product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human CD3
catalog :
344801
quantity :
25 μg
price :
36 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SK7
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 5:100; loading ...; fig 4a
Yamagishi M, Kubokawa M, Kuze Y, Suzuki A, Yokomizo A, Kobayashi S, et al. Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma. Nat Commun. 2021;12:4821 pubmed publisher
  • flow cytometry; human; loading ...; fig 2b
Altvater B, Kailayangiri S, Pérez Lanuza L, Urban K, Greune L, Flügge M, et al. HLA-G and HLA-E Immune Checkpoints Are Widely Expressed in Ewing Sarcoma but Have Limited Functional Impact on the Effector Functions of Antigen-Specific CAR T Cells. Cancers (Basel). 2021;13: pubmed publisher
  • flow cytometry; human; 1:50
Turner J, Kim W, Kalaidina E, Goss C, Rauseo A, Schmitz A, et al. SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans. Nature. 2021;595:421-425 pubmed publisher
  • flow cytometry; human; loading ...; fig s6-2
Kasatskaya S, Ladell K, Egorov E, Miners K, Davydov A, Metsger M, et al. Functionally specialized human CD4+ T-cell subsets express physicochemically distinct TCRs. elife. 2020;9: pubmed publisher
  • flow cytometry; human; loading ...; fig 2s5a
Ma T, Luo X, George A, Mukherjee G, Sen N, Spitzer T, et al. HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread. elife. 2020;9: pubmed publisher
  • flow cytometry; human; 3:50; loading ...; fig 3j
Park J, Botting R, Domínguez Conde C, Popescu D, Lavaert M, Kunz D, et al. A cell atlas of human thymic development defines T cell repertoire formation. Science. 2020;367: pubmed publisher
  • flow cytometry; human; loading ...; fig s6c
Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al. Spatiotemporal immune zonation of the human kidney. Science. 2019;365:1461-1466 pubmed publisher
  • flow cytometry; human; loading ...; fig s1
Meckiff B, Ladell K, McLaren J, Ryan G, Leese A, James E, et al. Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells. J Immunol. 2019;203:1276-1287 pubmed publisher
  • flow cytometry; human; loading ...; fig 4a
Richardson J, Armbruster N, Günter M, Henes J, Autenrieth S. Staphylococcus aureus PSM Peptides Modulate Human Monocyte-Derived Dendritic Cells to Prime Regulatory T Cells. Front Immunol. 2018;9:2603 pubmed publisher
  • flow cytometry; human; loading ...; fig 1
Harper I, Gjorgjimajkoska O, Siu J, Parmar J, Mulder A, Claas F, et al. Prolongation of allograft survival by passenger donor regulatory T cells. Am J Transplant. 2019;19:1371-1379 pubmed publisher
  • flow cytometry; mouse; 1:60; loading ...; fig 7a
Kiener R, Fleischmann M, Wiegand M, Lemmermann N, Schwegler C, Kaufmann C, et al. Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors. J Virol. 2018;92: pubmed publisher
  • flow cytometry; human; fig e1b
Maric J, Ravindran A, Mazzurana L, Björklund Ã, Van Acker A, Rao A, et al. Prostaglandin E2 suppresses human group 2 innate lymphoid cell function. J Allergy Clin Immunol. 2018;141:1761-1773.e6 pubmed publisher
  • flow cytometry; human; loading ...; fig 2e
Herndler Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, et al. Humanized mouse model supports development, function, and tissue residency of human natural killer cells. Proc Natl Acad Sci U S A. 2017;114:E9626-E9634 pubmed publisher
  • flow cytometry; human; loading ...; fig 4b
Nerdal P, Peters C, Oberg H, Zlatev H, Lettau M, Quabius E, et al. Butyrophilin 3A/CD277-Dependent Activation of Human ?? T Cells: Accessory Cell Capacity of Distinct Leukocyte Populations. J Immunol. 2016;197:3059-3068 pubmed
  • flow cytometry; human; fig s5
Pachnio A, Ciáurriz M, Begum J, Lal N, Zuo J, Beggs A, et al. Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium. PLoS Pathog. 2016;12:e1005832 pubmed publisher
  • flow cytometry; human; fig 2a
Ma Q, Garber H, Lu S, He H, Tallis E, Ding X, et al. A novel TCR-like CAR with specificity for PR1/HLA-A2 effectively targets myeloid leukemia in vitro when expressed in human adult peripheral blood and cord blood T cells. Cytotherapy. 2016;18:985-94 pubmed publisher
  • flow cytometry; human; loading ...; fig 4a
Tham M, Schlör G, Yerly D, Mueller C, Surbek D, Villiger P, et al. Reduced pro-inflammatory profile of γδT cells in pregnant patients with rheumatoid arthritis. Arthritis Res Ther. 2016;18:26 pubmed publisher
  • flow cytometry; human; fig s3
Milne P, Bigley V, Gunawan M, Haniffa M, Collin M. CD1c+ blood dendritic cells have Langerhans cell potential. Blood. 2015;125:470-3 pubmed publisher
  • flow cytometry; human
Chandran P, Keller A, Weinmann L, Seida A, Braun M, Andreev K, et al. The TGF-?-inducible miR-23a cluster attenuates IFN-? levels and antigen-specific cytotoxicity in human CD8? T cells. J Leukoc Biol. 2014;96:633-45 pubmed publisher
  • flow cytometry; mouse; fig 1
Chan W, Suwannasaen D, Throm R, Li Y, Eldridge P, Houston J, et al. Chimeric antigen receptor-redirected CD45RA-negative T cells have potent antileukemia and pathogen memory response without graft-versus-host activity. Leukemia. 2015;29:387-95 pubmed publisher
Xie C, Jiang B, Qin L, Tellides G, Kirkiles Smith N, Jane Wit D, et al. Complement-activated interferon-γ-primed human endothelium transpresents interleukin-15 to CD8+ T cells. J Clin Invest. 2020;130:3437-3452 pubmed publisher
Jacob F, Salinas R, Zhang D, Nguyen P, Schnoll J, Wong S, et al. A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity. Cell. 2020;180:188-204.e22 pubmed publisher
Abdel Gadir A, Stephen Victor E, Gerber G, Noval Rivas M, Wang S, Harb H, et al. Microbiota therapy acts via a regulatory T cell MyD88/RORγt pathway to suppress food allergy. Nat Med. 2019;: pubmed publisher
Li Y, Teteloshvili N, Tan S, Rao S, Han A, Yang Y, et al. Humanized Mice Reveal New Insights Into the Thymic Selection of Human Autoreactive CD8+ T Cells. Front Immunol. 2019;10:63 pubmed publisher
Backes C, Friedmann K, Mang S, Knörck A, Hoth M, Kummerow C. Natural killer cells induce distinct modes of cancer cell death: Discrimination, quantification, and modulation of apoptosis, necrosis, and mixed forms. J Biol Chem. 2018;293:16348-16363 pubmed publisher
Brinkmann C, Højen J, Rasmussen T, Kjær A, Olesen R, Denton P, et al. Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits Ex Vivo Lipopolysaccharide-Induced Inflammatory Responses. mSphere. 2018;3: pubmed publisher
Eriksson E, Milenova I, Wenthe J, Ståhle M, Leja Jarblad J, Ullenhag G, et al. Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus. Clin Cancer Res. 2017;23:5846-5857 pubmed publisher
Murayama M, Kakuta S, Inoue A, Umeda N, Yonezawa T, Maruhashi T, et al. CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis. Nat Commun. 2015;6:8483 pubmed publisher
product information
Antigen :
CD3
Apps. Abbrev. :
Flow Cytometry, ICC, IHC-F, Western Blotting
Cat # :
344801
Clone :
SK7
Item :
Purified anti-human CD3
Isotype :
Mouse IgG1, κ
Other Names :
T3, CD3ε
Size :
25 μg
Price (USD) :
36 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Application Notes :
Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections 4,5,8 , immunofluorescent staining 6 , and Western blotting 3 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA